Increased consumption of virgin olive oil, nuts, legumes, whole grains, and fish promotes HDL functions in humans
Author
Publication date
2019-01Abstract
Scope
To evaluate whether increases in the consumption of cardioprotective food groups (virgin olive oil, nuts, fruits/vegetables, legumes, whole grains, fish, and wine) are associated with improvements in high-density lipoprotein (HDL) functions in high cardiovascular risk subjects.
Methods and Results
The association between 1-year changes in food group consumption and HDL functionality traits in 296 high cardiovascular risk subjects is assessed. Increases in virgin olive oil (10 g d–1) and whole grain consumption (25 g d–1) are associated with increments in cholesterol efflux capacity (+0.7%, P = 0.026, and +0.6%, P = 0.017, respectively). Increases in nut (30 g d–1) and legume intake (25 g d–1) are linked to increments in paraoxonase-1 activity (+12.2%, P = 0.049, and +11.7%, P = 0.043, respectively). Legume intake increases are also related to decreases in cholesteryl ester transfer protein activity (–4.8%, P = 0.028). Fish consumption increments (25 g d–1) are associated with increases in paraoxonase-1 activity (+3.9%, P = 0.030) and declines in cholesteryl ester transfer protein activity (–1.6%, P = 0.021), HDL cholesterol concentrations (–1.1%, P = 0.039), and functions related to HDL levels (cholesterol efflux capacity, –1.1%, P = 0.010).
Conclusion
Increases in the consumption of virgin olive oil, nuts, legumes, whole grains, and fish (achievable through a regular diet) were associated with improvements in HDL functions in high cardiovascular risk subjects.
Document Type
Article
Document version
Accepted version
Language
English
Pages
5 p.
Publisher
Wiley Online Library
Is part of
Molecular nutrition and food research, 2019, 63(6): 1800847
Grant agreement number
info:eu-repo/grantAgreement/SUR del DEC/SGR/2014-SGR-240
info:eu-repo/grantAgreement/MINECO/ISCIII/CB06/03/0028
info:eu-repo/grantAgreement/MINECO/ISCIII/CD17/00122
info:eu-repo/grantAgreement/MINECO/ISCIII/CES12/025
info:eu-repo/grantAgreement/MINECO/ISCIII/JR14/00008
info:eu-repo/grantAgreement/MINECO/ISCIII/OBN17PI02
info:eu-repo/grantAgreement/MINECO/ISCIII/PI11/01647
info:eu-repo/grantAgreement/MINECO/ISCIII/PI15/00047
This item appears in the following Collection(s)
Rights
© Wiley-VCH Verlag GmbH i Co. KGaA
Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc-nd/4.0/