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Estimated substitution of tea or coffee for sugar-sweetened beverages was associated with lower type 2 diabetes incidence in case–cohort analysis across 8 European countries in the EPIC-InterAct study
(The Journal of nutrition, 2019, 149(11): 1985-1993, 2019-11)Background Beverage consumption is a modifiable risk factor for type 2 diabetes (T2D), but there is insufficient evidence to inform the suitability of substituting 1 type of beverage for another. Ob ... -
Plant foods, dietary fibre and risk of ischaemic heart disease in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort
(International Journal of Epidemiology, 2021, 50(1): 212-222, 2021-02)Background Epidemiological evidence indicates that diets rich in plant foods are associated with a lower risk of ischaemic heart disease (IHD), but there is sparse information on fruit and vegetable ... -
The Contradictions in the criteria for diagnosing hypermobile Ehlers–Danlos syndrome as reflecting some of the philosophical debates about the threshold between the normal and the pathological
(The Journal of Medicine and Philosophy, 2025, 16 d'abril: 1-14, 2025-04)The arrival of some diagnoses tends to bring about relief because it validates suffering and grants access to social legitimization, medical resources, and economic aid. This is the case of the Ehlers–Danlos ... -
Metabolic signatures of healthy lifestyle patterns and colorectal cancer risk in a European cohort
(Clinical Gastroenterology and Hepatology, 2022, 20(5): e1061-e1082, 2022-05)Background & Aims Colorectal cancer risk can be lowered by adherence to the World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) guidelines. We derived metabolic signatures of ... -
Adherence to the western, prudent and mediterranean dietary patterns and colorectal cancer risk: findings from the Spanish cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC-Spain)
(Nutrients, 2022, 14(15): 3085, 2022-07)The aim of this study was to explore the association between three previously identified dietary patterns (Western, Prudent, and Mediterranean) and colorectal cancer (CRC) risk by sex and cancer subtype. ... -
Prospective and Mendelian randomization analyses on the association of circulating fatty acid binding protein 4 (FABP‑4) and risk of colorectal cancer
(BMC Medicine, 2023, 21: 391, 2023-10)Background Fatty acid binding protein 4 (FABP-4) is a lipid-binding adipokine upregulated in obesity, which may facilitate fatty acid supply for tumor growth and promote insulin resistance and inflammation ... -
Diet and lifestyle in relation to small intestinal cancer risk: findings from the European Prospective Investigation into Cancer and Nutrition (EPIC)
(Cancer Causes and Control, 2023, 34: 927-937, 2023-06)Purpose The incidence of small intestinal cancer (SIC) is increasing, however, its aetiology remains unclear due to a lack of data from large-scale prospective cohorts. We examined modifiable risk ... -
Consumption of ultra-processed foods and risk of multimorbidity of cancer and cardiometabolic diseases: a multinational cohort study
(The Lancet Regional Health Europe, 2023, 35: 100771, 2023-12)Background It is currently unknown whether ultra-processed foods (UPFs) consumption is associated with a higher incidence of multimorbidity. We examined the relationship of total and subgroup consumption ... -
Sex- and site-specific associations of circulating lipocalin 2 and incident colorectal cancer: Results from the EPIC cohort
(International Journal of Cancer, 2025, 156(5): 930-942, 2024-11)Experimental research has uncovered lipocalin 2 (LCN2) as a novel biomarker implicated in the modulation of intestinal inflammation, metabolic homeostasis, and colon carcinogenesis. However, evidence ... -
Chrono-nutrition, chrono-type, and the prevalence of type 2 diabetes mellitus in a cross-sectional study from the EuroPean Prospective Investigation into Cancer and Nutrition (EPIC) study
(Nutrients, 2024, 16(16): 2598, 2024-08)Background: Previous studies have shown that meal timing, poor sleep quality, and chronotype may play a relevant role in the development of type 2 diabetes mellitus (T2DM). However, its relationship ... -
Multimorbidity in acute ischemic stroke and its impact on short-term mortality: A Chilean nationwide database analysis
(Journal of stroke and cerebrovascular diseases, 2025, 34(5): 108267, 2025-02)Background Multimorbidity predicts a worse prognosis for various diseases but its impact in people after an acute ischemic stroke (AIS) in developing societies is not well established. We aimed to ... -
Basic life-support learning in undergraduate students of sports sciences: efficacy of 150 minutes of training and retention after eight months
(International Journal of Environmental Research and Public Health, 2019, 16(23): 4771, 2019-11)Several professional groups, which are not health professionals, are more likely to witness situations requiring basic life support (BLS) due to the nature of their job. The aim of this study was to ... -
Safety of nanoparticle therapies during pregnancy: A systematic review and meta-analysis
(Journal of Controlled Release, 2025, 382: 113655, 2025-06)The exclusion of pregnant women from clinical trials has led to insufficient safety data for many treatments, making it necessary to evaluate their potential benefits and risks during preclinical stages. ... -
A pilot programme to teach pharmaco logy using the i nternational nonproprietary names in a pharmacy school in Spain
(Pharmacy Education, 2022, 22(1): 73-76, 2022-01)Introduction: In pharmacology lectures, one of the major challenges faced by students is how students can remember an increasing list of a large number of drug names. Although university teachers use ... -
Prevalence and risk factors of gestational diabetes in the health region of Lleida: a retrospective observational cohort study
(Journal of Endocrinological Investigation, 2023, 46: 2639-2646, 2023-06)Background Diabetes is a very common metabolic condition during pregnancy. The number of cases increases with age and obesity. The prevalence of pre-gestational diabetes and gestational diabetes (GD) ... -
Clinical utility and implementation of pharmacogenomics for the personalisation of antipsychotic treatments
(Pharmaceutics, 2024, 16(2): 244, 2024-02)Decades of pharmacogenetic research have revealed genetic biomarkers of clinical response to antipsychotics. Genetic variants in antipsychotic targets, dopamine and serotonin receptors in particular, ... -
Metabolic dysfunction-associated steatotic liver disease in severe obesity and concordance between Invasive (Biopsy) and noninvasive (OWLiver®) diagnoses
(Obesity Facts, 2024, 17(5): 473-482, 2024-06)Introduction: Nonalcoholic fatty liver disease (NAFLD), now termed metabolic dysfunction-associated steatotic liver disease (MASLD), is an escalating health concern linked to obesity and type 2 diabetes. ... -
Food insecurity and dietary diversity among food aid recipients in urban and rural areas at the covid-19 outbreak: An exploratory study
(World Food Policy, 2024, 10(1): 33-47, 2024-05)The covid-19 pandemic has affected food aid. This paper reports an exploratory study to estimate the prevalence and degree of food insecurity, household dietary diversity score (HDDS), and the association ... -
An automated classification pipeline for tables in pharmacokinetic literature
(Scientific reports, 2025, 15: 10071, 2025-03)Pharmacokinetic (PK) models are essential for optimising drug candidate selection and dosing regimens in drug development. Preclinical and population PK models benefit from integrating prior knowledge ... -
Determinants and outcomes of physical activity in patients with COPD: a systematic review
(Thorax, 2014, 69: 731-739, 2014-02)Background The relationship between physical activity, disease severity, health status and prognosis in patients with COPD has not been systematically assessed. Our aim was to identify and summarise ...