Recent Submissions
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Consumption of ultra-processed foods and risk of multimorbidity of cancer and cardiometabolic diseases: a multinational cohort study
(The Lancet Regional Health Europe, 2023, 35: 100771, 2023-12)Background It is currently unknown whether ultra-processed foods (UPFs) consumption is associated with a higher incidence of multimorbidity. We examined the relationship of total and subgroup consumption ... -
Sex- and site-specific associations of circulating lipocalin 2 and incident colorectal cancer: Results from the EPIC cohort
(International Journal of Cancer, 2025, 156(5): 930-942, 2024-11)Experimental research has uncovered lipocalin 2 (LCN2) as a novel biomarker implicated in the modulation of intestinal inflammation, metabolic homeostasis, and colon carcinogenesis. However, evidence ... -
Chrono-nutrition, chrono-type, and the prevalence of type 2 diabetes mellitus in a cross-sectional study from the EuroPean Prospective Investigation into Cancer and Nutrition (EPIC) study
(Nutrients, 2024, 16(16): 2598, 2024-08)Background: Previous studies have shown that meal timing, poor sleep quality, and chronotype may play a relevant role in the development of type 2 diabetes mellitus (T2DM). However, its relationship ... -
Multimorbidity in acute ischemic stroke and its impact on short-term mortality: A Chilean nationwide database analysis
(Journal of stroke and cerebrovascular diseases, 2025, 34(5): 108267, 2025-02)Background Multimorbidity predicts a worse prognosis for various diseases but its impact in people after an acute ischemic stroke (AIS) in developing societies is not well established. We aimed to ... -
Basic life-support learning in undergraduate students of sports sciences: efficacy of 150 minutes of training and retention after eight months
(International Journal of Environmental Research and Public Health, 2019, 16(23): 4771, 2019-11)Several professional groups, which are not health professionals, are more likely to witness situations requiring basic life support (BLS) due to the nature of their job. The aim of this study was to ... -
Safety of nanoparticle therapies during pregnancy: A systematic review and meta-analysis
(Journal of Controlled Release, 2025, 382: 113655, 2025-06)The exclusion of pregnant women from clinical trials has led to insufficient safety data for many treatments, making it necessary to evaluate their potential benefits and risks during preclinical stages. ... -
A pilot programme to teach pharmaco logy using the i nternational nonproprietary names in a pharmacy school in Spain
(Pharmacy Education, 2022, 22(1): 73-76, 2022-01)Introduction: In pharmacology lectures, one of the major challenges faced by students is how students can remember an increasing list of a large number of drug names. Although university teachers use ... -
Prevalence and risk factors of gestational diabetes in the health region of Lleida: a retrospective observational cohort study
(Journal of Endocrinological Investigation, 2023, 46: 2639-2646, 2023-06)Background Diabetes is a very common metabolic condition during pregnancy. The number of cases increases with age and obesity. The prevalence of pre-gestational diabetes and gestational diabetes (GD) ... -
Clinical utility and implementation of pharmacogenomics for the personalisation of antipsychotic treatments
(Pharmaceutics, 2024, 16(2): 244, 2024-02)Decades of pharmacogenetic research have revealed genetic biomarkers of clinical response to antipsychotics. Genetic variants in antipsychotic targets, dopamine and serotonin receptors in particular, ... -
Metabolic dysfunction-associated steatotic liver disease in severe obesity and concordance between Invasive (Biopsy) and noninvasive (OWLiver®) diagnoses
(Obesity Facts, 2024, 17(5): 473-482, 2024-06)Introduction: Nonalcoholic fatty liver disease (NAFLD), now termed metabolic dysfunction-associated steatotic liver disease (MASLD), is an escalating health concern linked to obesity and type 2 diabetes. ... -
Food insecurity and dietary diversity among food aid recipients in urban and rural areas at the covid-19 outbreak: An exploratory study
(World Food Policy, 2024, 10(1): 33-47, 2024-05)The covid-19 pandemic has affected food aid. This paper reports an exploratory study to estimate the prevalence and degree of food insecurity, household dietary diversity score (HDDS), and the association ... -
An automated classification pipeline for tables in pharmacokinetic literature
(Scientific reports, 2025, 15: 10071, 2025-03)Pharmacokinetic (PK) models are essential for optimising drug candidate selection and dosing regimens in drug development. Preclinical and population PK models benefit from integrating prior knowledge ... -
Determinants and outcomes of physical activity in patients with COPD: a systematic review
(Thorax, 2014, 69: 731-739, 2014-02)Background The relationship between physical activity, disease severity, health status and prognosis in patients with COPD has not been systematically assessed. Our aim was to identify and summarise ... -
Characterisation and prognosis of undiagnosed chronic obstructive pulmonary disease patients at their first hospitalisation
(BMC Pulmonary Medicine, 2015, 15: 4, 2015-01)Background Under-diagnosis of COPD is an important unmet medical need. We investigated the characteristics and prognosis of hospitalised patients with undiagnosed COPD. Methods The PAC-COPD cohort ... -
Long-term efficacy and effectiveness of a behavioural and community-based exercise intervention (Urban Training) to increase physical activity in patients with COPD: a randomised controlled trial
(European respiratory journal, 2018, 52(4):1800063, 2018-12)There is a need to increase and maintain physical activity in patients with chronic obstructive pulmonary disease (COPD). We assessed 12-month efficacy and effectiveness of the Urban Training intervention ... -
Validation of walking trails for the urban training of chronic obstructive pulmonary disease patients
(PLoS One, 2016, 11(1): e0146705, 2016-01)Purpose Accessible interventions to train patients with chronic obstructive pulmonary disease (COPD) are needed. We designed urban trails of different intensities (low, moderate and high) in different ... -
The PROactive instruments to measure physical activity in patients with chronic obstructive pulmonary disease
(European respiratory journal, 2015, 46(4):988-1000, 2015-06)No current patient-centred instrument captures all dimensions of physical activity in chronic obstructive pulmonary disease (COPD). Our objective was item reduction and initial validation of two instruments ... -
Preference trials: An underexplored design in musculoskeletal research
(JOSPT Methods, 2025, 1(2): 1-12, 2025-03)BACKGROUND: Incorporating patients’ preferences into randomized controlled trials (RCTs) enhances the relevance and applicability of research findings to clinical practice. Person- and patient-centered ... -
Relation between length of exposure to epidural analgesia during labour and birth mode
(International Journal of Environmental Research and Public Health, 2019, 16(16): 2928, 2019-08)Objective: To appraise the relationship between the length of exposure to epidural analgesia and the risk of non-spontaneous birth, and to identify additional risk factors. This study is framed within ... -
The Chester step test is a reproducible tool to assess exercise capacity and exertional desaturation in post-COVID-19 patients
(Healthcare, 2023, 11(1), 51, 2022-12)Many people recovering from an acute episode of coronavirus disease (COVID-19) experience prolonged symptoms. Exercise testing is a feasible and cost-effective option for assessing exercise tolerance, ...