Browsing Articles publicats en revistes by Subject "54"
Now showing items 1-20 of 89
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1,2,3-Triazole Derivatives as Novel Antifibrinolytic Drugs
(International Journal of Molecular Sciences, 23(23), 2022, 14942, 2022)Fibrinolysis is a natural process that ensures blood fluidity through the removal of fibrin deposits. However, excessive fibrinolytic activity can lead to complications in different circumstances, such ... -
15 años de laboratorios virtuales en química (I) ¿Qué son? ¿Para qué sirven?
(Alambique. Vol.76 (2014), p.55-62, 2014)Hace unos 15 años, entre 1997 y 2000, aparecieron un conjunto de entornos de simulación que representan un laboratorio de química. Se recogen en este artículo, el estado actual de siete de estas ... -
1H-Pyrazolo[3,4-b]pyridines: Synthesis and Biomedical Applications
(Molecules 27(7), 2022, 2237, 2022)Pyrazolo[3,4-b]pyridines are a group of heterocyclic compounds presenting two possible tautomeric forms: the 1H- and 2H-isomers. More than 300,000 1H-pyrazolo[3,4-b]pyridines have been described which ... -
3D Printing of Silicone Organogel Elastomers for Structured Soft Biomaterials
(ACS Biomaterials Science & Engineering 2025, 11 (3), 1806–1817, 2025-03-10)Creating customizable soft medical implants and devices tailored to patient-specific anatomy represents a significant challenge in healthcare, requiring 3D-printable materials with viscoelastic properties ... -
9-Aryl-phenalenones: Bioinspired thermally reversible photochromic compounds for photoswitching applications in the pico-to milliseconds range
(Dyes and Pigments 2021, 186, 2021-02)Ultrafast photochromic molecules are being actively investigated to meet the demand for fast optical switching systems. Inspired on the irreversible cyclization of 9-phenylphenalenone plant metabolites ... -
A near-infrared light-activatable Ru(ii)-coumarin photosensitizer active under hypoxic conditions
(Chemical Space 2023, 15(26), 2023-07-14)Photodynamic therapy (PDT) represents a promising approach for cancer treatment. However, the oxygen dependency of PDT to generate reactive oxygen species (ROS) hampers its therapeutic efficacy, especially ... -
A novel fluoro-chromogenic click reaction for the labelling of proteins and nanoparticles with near-IR theranostic agents
(Chemical Communications. Vol.51, n.26 (2015), p.5586-5589, 2014-12)Reaction of porphycene isothiocyanates with primary and secondary amines leads to the formation of thiazolo[4,5-c]porphycenes, with a substantial shift in the absorption and fluorescence spectra. The ... -
A simple AI-driven process intensification protocol for active pharmaceutical ingredients synthesis
(Chemical Engineering Journal Advances 2025, 24, 2025-11)The synthesis of active pharmaceutical ingredients (APIs) traditionally relies on batch reactors, which often exhibit challenges in terms of both selectivity and heat transfer control. This study ... -
Absolute environmental sustainability assessment of emerging working fluids in organic rankine cycles
(ACS Sustainable Chemistry & Engineering 2025, 13(18), 6685–6695, 2025-05-12)New working fluids (WFs) have been recently proposed to enhance the environmental performance of Organic Rankine Cycles (ORCs) in waste heat recovery systems. However, a critical gap remains in the ... -
Acanthospermum hispidum and Its Metabolite Stigmasterol Modulates Anti-Inflammatory Antagonism of COX-1 and TGF-β
(Chemistry & Biodiversity 2026, 23 (1), 2026-01)Acanthospermum hispidum (AH) leaves have been widely used in traditional medicine for inflammation. In this study, the anti-inflammatory effect of AH was evaluated, and a possible mechanism was predicted ... -
Accurate and model-free control function for a single stage transcritical refrigerator cycle
(ACS Omega. Vol.5, n.30 (2020) p.19217-19226, 2020-08)Transcritical cycles are a successful and probed system in engineering practices, particularly in refrigeration. Therefore, their optimization is a critical factor in the design, control, and operation ... -
Activitats contextualitzades en el laboratori virtual
(Educació Química. N.14 (2013), p.48-55, 2013)En aquest article es presenten quatre activitats noves basades en la utilització del laboratori virtual de «The ChemCollective», destinades a l'ensenyament de la química a l'educació secundària, i se'n ... -
Ag(I) ions working as a hole-transfer mediator in photoelectrocatalytic water oxidation on WO3 film
(Nature Communications. Vol. 11, n.1 (2020), 967, 2020-02)Ag(I) is commonly employed as an electron scavenger to promote water oxidation. In addition to its straightforward role as an electron acceptor, Ag(I) can also capture holes to generate the high-valent ... -
Algebraic surrogate-based flexibility analysis of process units with complicating process constraints
(Computers & Chemical Engineering. 2024;184:108630, 2024-03-11)Flexibility analyses are widespread in chemical engineering to quantify allowed deviations from nominal conditions. Standard approaches to perform flexibility analysis can be hard to apply if process ... -
Ammonium trifluoroborate-modified poly(β-aminoesters): A case study for PET-guided in vivo pharmacokinetic studies of a non-viral gene delivery system
(Journal of Controlled Release. 2023;358:739-751, 2023-05-27)Nucleic acid-based therapies have become a game-changing player in our way of conceiving pharmacology. Nevertheless, the inherent lability of the phosphodiester bond of the genetic material with respect ... -
An Ultra-Long-Lived Triplet Excited State in Water at Room Temperature: Insights on the Molecular Design of Tridecafullerenes
(Angewandte Chemie International Edition, 2021-05-13)Suitably engineered molecular systems exhibiting triplet excited states with very long lifetimes are important for high-end applications in nonlinear optics, photocatalysis, or biomedicine. We report ... -
Analyzing a virtual-lab based contextualized activity from action logs
(Procedia - Social and Behavioral Sciences 182 (2015) 441-447, 2015-05-13)In this paper, we present and analyze a virtual-lab based activity oriented as an application of the stoichiometry concepts that appear in the first year of the Spanish Bachillerato (16-17 year old). ... -
Análisis simultáneo de aflatoxinas y ocratoxina A en compost por HPLC-MS
(Afinidad. Vol.66, n.546 (2010), p.94-99, 2010-03)Las aflatoxinas y ocratoxina A son las micotoxinas más estudiadas debido a su elevada toxicidad y amplia distribución. En este trabajo se describe un método de análisis simultáneo de las aflatoxinas ... -
Assessing the potential of photosensitizing flavoproteins as tags for correlative microscopy
(Chemical Communications. Vol.52, n.54 (2016), p.8405-8408, 2016-06)Photosensitizing flavoproteins have great potential as tags for correlative light and electron microscopy (CLEM). We examine the photostability of miniSOG mutants and their ability to photooxidize ... -
Bacteriophobic Zwitterionic/Dopamine Coatings for Medical Elastomers
(Advanced Materials Interfaces, 2022, 9(30), 2201152, 2022)Despite modern advancements in sterilization and medical practices, bacterial infections remain a significant concern in the implantation of medical devices. There is currently an urgent need for ...