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Pharmacological modulation of behaviour, serotonin and dopamine levels in daphnia magna exposed to the monoamine oxidase inhibitor deprenyl
(Toxics, 2021-08-09)This study assessed the effects of the monoamine oxidase (MAO) inhibitor deprenyl in Daphnia magna locomotor activity. The mechanisms of action of deprenyl were also determined by studying the relationship ... -
Glyphosate targets fish monoaminergic systems leading to oxidative stress and anxiety
(Environment International, 2020-11-18)Glyphosate is the active ingredient of some of the most highly produced and used herbicides worldwide. The intensive applications of glyphosate-based herbicides and its half-life in water lead to its ... -
Differential modulation of the central and peripheral monoaminergic neurochemicals by deprenyl in Zebrafish Larvae
(Toxics, 2021-05-23)Zebrafish embryos and larvae are vertebrate models increasingly used in translational neuroscience research. Behavioral impairment induced by the exposure to neuroactive or neurotoxic compounds is ... -
Extracellular vesicles and their current role in cancer immunotherapy
(Cancers, 2021-05-10)Extracellular vesicles (EVs) are natural particles formed by the lipid bilayer and released from almost all cell types to the extracellular environment both under physiological conditions and in presence ... -
Analytical parameters of a novel glucose biosensor based on grafted PFM as a covalent immobilization technique
(Sensors, 2021-06-15)Bioanalytical methods, in particular electrochemical biosensors, are increasingly used in different industrial sectors due to their simplicity, low cost, and fast response. However, to be able to reliably ... -
Experimental, computational, and dimensional analysis of the mechanical performance of fused filament fabrication parts
(Polymers, 2021-05-27)Process parameters in Additive Manufacturing (AM) are key factors in the mechanical performance of 3D-printed parts. In order to study their effect, a three-zone model based on the printing pattern was ... -
Defined D-hexapeptides bind CUG repeats and rescue phenotypes of myotonic dystrophy myotubes in a Drosophila model of the disease
(Scientific Reports, 2021-09-30)In Myotonic Dystrophy type 1 (DM1), a non-coding CTG repeats rare expansion disease; toxic double-stranded RNA hairpins sequester the RNA-binding proteins Muscleblind-like 1 and 2 (MBNL1 and 2) and ... -
Role of Survivin in Bladder Cancer: Issues to Be Overcome When Designing an Efficient Dual Nano-Therapy
(Pharmaceutics, 2021-11-19)Bladder cancer is the 10th most diagnosed cancer, with almost 10 M cancer deaths last year worldwide. Currently, chemotherapy is widely used as adjuvant therapy after surgical transurethral resection. ... -
Syndecans and Pancreatic Ductal Adenocarcinoma
(Biomolecules, 2021-02-25)Pancreatic Ductal Adenocarcinoma (PDAC) is a fatal disease with poor prognosis because patients rarely express symptoms in initial stages, which prevents early detection and diagnosis. Syndecans, a ... -
Transglycosylation Activity of Engineered Bifidobacterium Lacto-N-Biosidase Mutants at Donor Subsites for Lacto-N-Tetraose Synthesis
(International Journal of Molecular Sciences, 2021-03-21)The health benefits of human milk oligosaccharides (HMOs) make them attractive targets as supplements for infant formula milks. However, HMO synthesis is still challenging and only two HMOs have been ... -
Process design for the recovery of waste refrigerants using deep eutectic solvents
(Journal of Environmental Chemical Engineering, 2023-06-01)The environmental impact on climate change of fluorinated gases (F-gases), used mainly in refrigeration applications, is boosting the search of new recovery processes that would allow their reuse in a ... -
Design of tropinium-functionalized anion exchange membranes for acid recovery via diffusion dialysis process
(Environmental Research, 2023-07-15)Diffusion dialysis (DD) process utilizing anion exchange membranes (AEMs) is an environmentally-friendly and energy-efficient technology. From acidic wastewater, DD is needed for acid recovery. This ... -
Removal of chromium (VI) by commercial anion exchange membrane BII from an aqueous solution: Adsorption kinetic, equilibrium and thermodynamic studies
(Inorganic Chemistry Communications, 2023-06-01)This work reports chromium (Cr(VI)) adsorption from an aqueous solution onto anion exchange membrane (AEM) BII. The Cr(VI) percentage adsorption was increased from 71 to 82 %, 70 to 92 % and 72 to 86 % ... -
Monitoring Tools for the Development of High Cell Density Culture Strategies
(Cell Culture Engineering and Technology. Cell Engineering, 2022-02-20)Biopharmaceuticals market has been constantly increasing during the last years, what is transforming the manufacturing industry of biomolecules. The efforts have been put into better understanding how ... -
Nanoscale characterization coupled to multi-parametric optimization of Hi5 cell transient gene expression
(Applied Microbiology and Biotechnology, 2018-10-13)Polyethylenimine (PEI)-based transient gene expression (TGE) is nowadays a well-established methodology for rapid protein production in mammalian cells, but it has been used to a much lower extent in ... -
Parameter screening of a VPSA cycle with automated breakthrough control for carbon capture
(Fuel, 2023-05-01)Vacuum pressure swing adsorption (VPSA) is an efficient technology that can be used for carbon capture from combustion stationary sources. However, VPSA is a cyclic and complex process that involves ... -
Metabolic flux balance analysis during lactate and glucose concomitant consumption in HEK293 cell cultures
(Biotechnology and Bioengineering, 2018-10-26)At early stages of the exponential growth phase in HEK293 cell cultures, the tricarboxylic acid cycle is unable to process all the amount of NADH generated in the glycolysis pathway, being lactate the ... -
Development of a non-viral platform for rapid virus-like particle production in Sf9 cells
(Journal of Biotechnology, 2020-07-11)Insect cells have shown a high versatility to produce multiple recombinant products. The ease of culture, low contamination risk with human pathogens and high expression capacity makes an attractive ... -
Efficient extracellular vesicles freeze-dry method for direct formulations preparation and use
(Colloids and Surfaces B: Biointerfaces, 2022-07-31)Despite the great knowledge achieved in the field of extracellular vesicles (EVs), the short lifetime of EVs liquid formulation still hampers the transfer of EVs technology to clinical applications. In ... -
Board gender quotas, female directors and corporate tax aggressiveness: A causal approach
(International Review of Financial Analysis, 2021-12-17)As a result of a mandatory board gender quota regulation, the percentage of female directors in Norway increased from around 5% in 2001 to over 40% in 2007, while it remained stable in neighbouring ...