Recerca: Recent submissions

Now showing items 321-340 of 3178

    • Current progress in bionanomaterials to modulate the epigenome 

      Rhodes, Anna D. Y.; Duran Mota, José Antonio; Oliva, Núria (Biomaterials Science 2022, 18, 5021-5358, 2022)
      Recent advances in genomics during the 1990s have made it possible to study and identify genetic and epigenetic responses of cells and tissues to various drugs and environmental factors. This has ...

    • Deconstructing Markush: Improving the R&D Efficiency Using Library Selection in Early Drug Discovery 

      Manen Freixa, Leticia; Borrell Bilbao, José Ignacio; Teixidó i Closa, Jordi; Estrada Tejedor, Roger (Pharmaceuticals 2022, 15(9), 1159, 2022)
      Most of the product patents claim a large number of compounds based on a Markush structure. However, the identification and optimization of new principal active ingredients is frequently driven by a ...

    • Reivindicar els drets humans en un món convuls 

      Mateos, Oscar (Qüestions de vida cristiana, núm. 277, 2023, 2023)

    • Bioprocess Strategies for Vitamin B12 Production by Microbial Fermentation and Its Market Applications 

      Calvillo, Alvaro; Pellicer Moya, Maria Teresa; Carnicer, Marc; Planas, Antoni (Planas Sauter) (Bioengineering 2022, 9(8), 365, 2022)
      Vitamin B12 is a widely used compound in the feed and food, healthcare and medical industries that can only be produced by fermentation because of the complexity of its chemical synthesis. For this ...

    • Increased consumption of virgin olive oil, nuts, legumes, whole grains, and fish promotes HDL functions in humans 

      Hernáez, Álvaro; Sanllorente Melenchon, Albert; Castañer, Olga; Martínez-González, Miguel Ángel, 1957-; Ros Rahola, Emilio; Pintó Sala, Xavier; Estruch Riba, Ramon; Salas Salvadó, Jordi; Corella Piquer, Dolores; Alonso Gómez, Ángel M.; Serra Majem, Lluís; Fiol, Miquel; Lapetra, José; Gómez-Gracia, Enrique; de la Torre, Rafael; Lamuela Raventós, Rosa Ma.; Fitó Colomer, Montserrat (Molecular nutrition and food research, 2019, 63(6): 1800847, 2019-01)
      Scope To evaluate whether increases in the consumption of cardioprotective food groups (virgin olive oil, nuts, fruits/vegetables, legumes, whole grains, fish, and wine) are associated with improvements ...

    • A hybrid numerical-experimental strategy for predicting mechanical response of components manufactured via FFF 

      Dialami, Narges; Chiumenti, Michele; Cervera, Miguel; Chasco, Uxue; Reyes Pozo, Guillermo; Pérez Martínez, M. (Marco) (Composite Structures 298 (2022) 115998, 2022)
      In this paper a new methodology developed for predicting the mechanical performance of the structures additively manufactured by Fused Filament Fabrication is presented. The novelty of the approach ...

    • A Double Payload Complex between Hypericin and All-trans Retinoic Acid in the β-Lactoglobulin Protein 

      Rodríguez Amigo, Beatriz; Hally, Cormac; Roig Yanovsky, Núria; Delcanale, Pietro; Abbruzzetti, Stefania; Agut Bonsfills, Montserrat; Viappiani, Cristiano; Nonell, Santi (Antibiotics, 11(2), 2022, 282, 2022)
      Combined therapies are usually used to treat acne vulgaris since this approach can tackle various foci simultaneously. Using a combination of spectroscopic, computational, and microbiological techniques ...

    • A computational drop-in assessment of hydrofluoroethers in Organic Rankine Cycles 

      Jovell, Daniel; González Olmos, Rafael; Llovell Ferret, Félix Lluís (Energy, 254 Part B (2022), 124319, 2022)
      Organic Rankine Cycles (ORCs) are experiencing a growing interest due to their ability to generate electricity from residual low waste heat sources. HFC-245fa is a representative working fluid for ORC ...

    • 1H-Pyrazolo[3,4-b]pyridines: Synthesis and Biomedical Applications 

      Donaire-Arias, Ana; Montagut, Ana Maria; Puig de la Bellacasa Cazorla, Raimon; Teixidó i Closa, Jordi; Borrell Bilbao, José Ignacio (Molecules 27(7), 2022, 2237, 2022)
      Pyrazolo[3,4-b]pyridines are a group of heterocyclic compounds presenting two possible tautomeric forms: the 1H- and 2H-isomers. More than 300,000 1H-pyrazolo[3,4-b]pyridines have been described which ...

    • 1,2,3-Triazole Derivatives as Novel Antifibrinolytic Drugs 

      Bosch-Sanz, Oriol; Rabadà, Yvette; Biarnés Fontal, Xevi; Pedreño, Javier; Caveda, Luis; Balcells Camps, Mercedes; Martorell López, Jordi; Sánchez García, David (International Journal of Molecular Sciences, 23(23), 2022, 14942, 2022)
      Fibrinolysis is a natural process that ensures blood fluidity through the removal of fibrin deposits. However, excessive fibrinolytic activity can lead to complications in different circumstances, such ...

    • Automotive Electrification Challenges Shown by Real-World Driving Data and Lifecycle Assessment 

      Neidhardt, Michael; Mas-Peiro, Jordi; Schneck, Antonia; Pou Ibar, Josep Oriol, 1980-; González Olmos, Rafael; Kwade, Arno; Schmuelling, Benedikt (Sustainability 2022, 14(23), 15972, 2022)
      Electric mobility is considered a solution to reduce carbon emissions. We expanded a lifecycle assessment with data on technical limitations and driving habits (based on real-world data) in order to ...

    • Bacteriophobic Zwitterionic/Dopamine Coatings for Medical Elastomers 

      Texidó, Robert; Cabanach, Pol; Kaplan, Richard; García Bonillo, Cristina; Pérez, Darío; Zhang, Shuo; Borrós i Gómez, Salvador; Pena-Francesch, Abdon (Advanced Materials Interfaces, 2022, 9(30), 2201152, 2022)
      Despite modern advancements in sterilization and medical practices, bacterial infections remain a significant concern in the implantation of medical devices. There is currently an urgent need for ...

    • BBX16 mediates the repression of seedling photomorphogenesis downstream of the GUN1/GLK1 module during retrograde signalling 

      Veciana, Nil; Martín, Guiomar; Leivar Rico, Pablo; Monte, Elena (New Phytologist 2022, 234(1), 93-106, 2022)
      Plastid-to-nucleus retrograde signalling (RS) initiated by dysfunctional chloroplasts impact photomorphogenic development. We have previously shown that the transcription factor GLK1 acts downstream of ...

    • Behavioural and neurochemical effects after repeated administration of N-ethylpentylone (ephylone) in mice 

      Espinosa Velasco, María; Reguilón, Marina D.; Bellot, Marina; Nadal Gratacós, Núria; Berzosa Rodríguez, Xavier; Puigseslloses, Pol; Gómez Canela, Cristian; Rodríguez Arias, Marta; Pubill, David; Camarasa, Jordi; Fonseca, David; López-Arnau, Raúl (Journal of Neurochemistry, 2022, 160(2), 218-233, 2022)
      N-ethyl-pentylone (NEP), also known as ‘ephylone’ and N-ethylnorpentylone, has been identified as one of the most recent novel psychostimulants to emerge into the illicit drug market and it has been ...

    • Mediterranean diet and antihypertensive drug use: a randomized controlled trial 

      Ribó-Coll, Margarita; Lassale, Camille; Sacanella Meseguer, Emilio; Ros Rahola, Emilio; Toledo, Estefanía; Sorlí, José V.; Babio, Nancy; Lapetra, José; Gómez-Gracia, Enrique; Alonso Gómez, Ángel M.; Fiol, Miquel; Serra Majem, Lluís; Pintó Sala, Xavier; Castañer, Olga; Díez Espino, Javier; González, José I.; Becerra-Tomás, Nerea; Cofán Pujol, Montserrat; Díaz López, Andrés; Estruch Riba, Ramon; Hernáez, Álvaro (Journal of hypertension, 2021, 39(6): 1230-1237, 2021-06)
      Objective: To examine in older individuals at high cardiovascular risk whether following a Mediterranean diet decreased the necessity of antihypertensive drugs and modulated their associated cardiovascular ...

    • Exceso de peso en España: situación actual, proyecciones para 2030 y sobrecoste directo estimado para el Sistema Nacional de Salud 

      Hernáez, Álvaro; Zomeño, Dolors; Degano, Irene R.; Pérez Fernández, Sílvia; Goday, Alberto; Vila, Joan; Civeira, Fernando; Moure, Ricardo; Marrugat, Jaume (Revista española de cardiología, 2019, 72(11): 916-924, 2019-11)
      Introducción y objetivos El exceso de peso potencia algunas enfermedades crónicas y reduce la calidad de vida, y su prevalencia crece en todo el mundo. El objetivo es estimar la evolución del exceso ...

    • Association of physical activity with high-density lipoprotein functionality in a population-based cohort: the REGICOR study 

      Viadas, Raúl; Toloba, Andrea; Fernández, Isabel; Sayols Baixeras, Sergi; Hernáez, Álvaro; Schroeder, Helmut; Degano, Irene R.; Lassale, Camille; Marrugat, Jaume; Elosua Llanos, Roberto (Revista española de cardiología, 2023, 76(2): 86-93, 2023-02)
      Introduction and objectives To determine the dose-response association between current and past leisure-time physical activity (LTPA), total and at different intensities, and high-density lipoprotein ...

    • 3,4-Methylenedioxy methamphetamine, synthetic cathinones and psychedelics: From recreational to novel psychotherapeutic drugs 

      López-Arnau, Raúl; Camarasa, Jordi; Carbó, Marcel·lí; Nadal Gratacós, Núria; Puigseslloses, Pol; Espinosa Velasco, María; Urquizu, Edurne; Fonseca, David; Pubill, David (Frontiers in Psychiatry, 2022)
      The utility of classical drugs used to treat psychiatric disorders (e.g., antidepressants, anxiolytics) is often limited by issues of lack of efficacy, delayed onset of action or side effects. Psychoactive ...

    • The Soundscape of the COVID-19 Lockdown: Barcelona Noise Monitoring Network Case Study † 

      Anguera, Jaume; Martinez-Suquia, Carme; Alsina-Pagès, Rosa Ma; Bergada, Pau (International Journal of Environmental Research and Public Health, 2021-05-28)
      The lockdown social measures in Spain due to COVID-19 caused a significant decrease in urban noise levels, which was observed in most of the large cities. This paper presents an analysis of the noise ...

    • Sons al Balcó: A Comparative Analysis of WASN-Based LAeq Measured Values with Perceptual Questionnaires in Barcelona during the COVID-19 Lockdown 

      Anguera, Jaume; Bergada, Pau; Dorca, Enric; Martinez-Suquia, Carme (Sensors, 2024-03-03)
      improvement in the urban noise pollution that could be objectively measured in those cities with acoustic sensor networks deployed. This significant change in the urban soundscapes was also perceived ...