Clinical impact of electronic monitoring devices of inhalers in adults with asthma or COPD: a systematic review and meta-analysis
Author
Publication date
2023-03Abstract
We conducted a systematic review and meta-analysis to gain insight into the characteristics and clinical impact of electronic monitoring devices of inhalers (EMDs) and their clinical interventions in adult patients with asthma or COPD. The search included PubMed, Web of Science, Cochrane, Scopus and Embase databases, as well as official EMDs websites. We found eight observational studies and ten clinical trials, assessing a wide range of clinical outcomes. Results from the meta-analysis on adherence to inhalers in a period over three months were favourable in the EMD group (fixed effects model: SMD: 0.36 [0.25–0.48]; random effects model SMD: 0.41 [0.22–0.60]). An exploratory meta-analysis found an improvement in ACT score (fixed effect model SMD: 0.25 [0.11–0.39]; random effects model: SMD: 0.47 [−0.14–1.08]). Other clinical outcomes showed mixed results in the descriptive analyses. The findings of this review highlight the benefits of EMDs in the optimization of adherence to inhaled therapy as well as the potential interest in other clinical outcomes.
Document Type
Article
Document version
Published version
Language
English
Subject (CDU)
615 - Pharmacology. Therapeutics. Toxicology
616.2 - Pathology of the respiratory system. Complaints of the respiratory organs
Keywords
Asma
Pulmons -- Malalties obstructives
COPD
Inhaladors
Medicaments -- Monitoratge
Metaanàlisi
Pages
25 p.
Publisher
MDPI
Is part of
Pharmaceuticals, 2023, vol. 16, núm. 3, 414
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Rights
© L'autor/a
Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by/4.0/