Browsing IQS by Title
Now showing items 185-204 of 317
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Mandatory joint audit and audit quality in the context of the European blue chips
(Journal of Business Economics & Management, 2021-10-13)This study investigates audit quality under joint and single audit regimes with a sample of large European firms. Both, the economic relevance of these companies, and the fact that the impact of joint ... -
Mechanical performance of 3D-printed biocompatible polycarbonate for biomechanical applications
(Polymers. Vol.13, n.21 (2021), 3669, 2021-10)Additive manufacturing has experienced remarkable growth in recent years due to the customisation, precision, and cost savings compared to conventional manufacturing techniques. In parallel, materials ... -
Mechanical strengthening in S235JR steel sheets through vibration-assisted ball burnishing
(Metals. Vol.10, n.8 (2020), 1010, 2020-07)The superficial effect of hardening caused after vibration-assisted ball burnishing and its consequences in the tensile behavior of a carbon steel material are studied in this paper. As ball burnishing ... -
Metabolic flux balance analysis during lactate and glucose concomitant consumption in HEK293 cell cultures
(Biotechnology and Bioengineering, 2018-10-26)At early stages of the exponential growth phase in HEK293 cell cultures, the tricarboxylic acid cycle is unable to process all the amount of NADH generated in the glycolysis pathway, being lactate the ... -
Un método para la simulación de columnas de adsorción
(Afinidad. Vol.68, n.552 (2011), p.86-94, 2011-03)Entre los procesos de separación en continuo para productos de alto valor añadido, se abre camino en los últimos años la utilización del “lecho móvil simulado” (Simulated Moving Bed). Para el diseño y ... -
Modelos no lineales de previsión para series temporales de interés farmacéutico. Aplicación al caso de la escarlatina.
(Afinidad. Vol.65, n.533 (2008), p.20-25, 2008-01)En este trabajo se presentan los resultados obtenidos tras el ajuste de un modelo no lineal y un modelo robusto de predicción a la serie temporal correspondiente a la incidencia de la escarlatina en ... -
Un modèle épistémologique de référence pour la recherche sur l’algèbre élémentaire
(Nouveaux cahiers de la recherche en éducation. Vol.22, n.1 (2020), p.123–144, 2020-06)La théorie anthropologique du didactique attribue un rôle déterminant au questionnement du savoir mathématique et propose comme outil d’analyse l’élaboration de modèles épistémologiques de référence ... -
Molecular basis of the selective binding of MDMA enantiomers to the Alpha4Beta2 nicotinic receptor subtype: synthesis, pharmacological evaluation and mechanistic studies
(European Journal of Medicinal Chemistry. Vol.81 (2014), p.35-46, 2014-06)The α4β2 nicotinic acetylcholine receptor (nAChR) is a molecular target of 3,4-methylenedioxymethamphetamine (MDMA), a synthetic drug also known as ecstasy, and it modulates the MDMA-mediated reinforcing ... -
Monitoring Tools for the Development of High Cell Density Culture Strategies
(Cell Culture Engineering and Technology. Cell Engineering, 2022-02-20)Biopharmaceuticals market has been constantly increasing during the last years, what is transforming the manufacturing industry of biomolecules. The efforts have been put into better understanding how ... -
Morin flavonoid adsorbed on mesoporous silica, a novel antioxidant nanomaterial
(Plos One, 2016, vol.11, 2016-11-03)Morin (2´,3, 4´,5,7-pentahydroxyflavone) is a flavonoid with several beneficial health effects. However, its poor water solubility and it sensitivity to several environmental factors avoid its use in ... -
Morphology effects on singlet oxygen production and bacterial photoinactivation efficiency by different silica-protoporphyrin IX nanocomposites
(RSC Advances. Vol.7, n.24 (2017), p.14422-14429, 2017-03)Different silica-protoporphyrin IX (PpIX) nanocomposites have been synthesized to evaluate the dependence of singlet oxygen production and bacterial inactivation efficiency on the morphology of the ... -
Multiscale modeling for complex chemical systems: highlights about the Nobel Prize in Chemistry 2013
(Afinidad. Vol.71, n.566 (2014), p.89-94, 2014-04)The Nobel Prize in Chemistry 2013 was awarded jointly to Martin Karplus, Michael Levitt and Arieh Warshel for the development of multiscale models for complex chemical systems. From the simplest ... -
Nanomedicine in non-small cell lung cancer: from conventional treatments to immunotherapy
(Cancers. Vol.12, n.6 (2020), 1609, 2020-06)Non-small cell lung cancer (NSCLC) remains the most common cause of cancer-related mortality. The heterogeneous nature of this disease hinders its diagnosis and treatment, requiring continuous advances ... -
Nanopartículas de sílice: preparación y aplicaciones en biomedicina
(Afinidad. Vol.71, n.565 (2014), p.20-31, 2014-01)Actualmente, un importante número de avances científicos se fundamentan en la utilización de nanopartículas cómo superficies de actuación, vehículos de transporte, en procesos relacionados con aplicaciones ... -
Nanoscale characterization coupled to multi-parametric optimization of Hi5 cell transient gene expression
(Applied Microbiology and Biotechnology, 2018-10-13)Polyethylenimine (PEI)-based transient gene expression (TGE) is nowadays a well-established methodology for rapid protein production in mammalian cells, but it has been used to a much lower extent in ... -
Nb–C thin films prepared by DC-MS and HiPIMS: Synthesis, structure, and tribomechanical properties
(Surface and Coatings Technology. Vol.422 (2021), 127569, 2021-09-25)Nanostructured Nb-C thin films were prepared by direct current magnetron sputtering (DC-MS) and high-power impulse magnetron sputtering (HiPIMS). The films were characterized in depth by X-ray diffraction ... -
New developments in vertebroplasty materials
(Afinidad. Vol.75, n.583 (2018), p.165-174, 2018-07)Increasing life expectancy is leading to an increase in age-related diseases, like osteoporosis, which often involve the breakdown of bone. One of the main problems related with such disease is the ... -
Nitrogen positional scanning in tetramines active against HIV-1 as potential CXCR4 inhibitors
(Organic & Biomolecular Chemistry. Vol.14, n.4 (2016), p.1455-1472, 2015-12)The paradigm, derived from bicyclams and other cyclams, by which it is necessary to use the p-phenylene moiety as the central core in order to achieve high HIV-1 antiviral activities has been reexamined ... -
Una nova taula periòdica per a l'ensenyament secundari
(Educació Química. N.15 (2013), p.62, 2015) -
Novel grafted electrochemical interface for covalent glucose oxidase immobilization using reactive pentafluorophenyl methacrylate
(Colloids and Surfaces B: Biointerfaces, 2018-12-01)One of the most important factors for the proper functioning of enzymatic electrochemical biosensors is the enzyme immobilization strategy. In this work, glucose oxidase was covalently immobilized using ...