Now showing items 1-20 of 643

    • Acute Paraoxon-Induced Neurotoxicity in a Mouse Survival Model: Oxidative Stress, Dopaminergic System Alterations and Memory Deficits 

      Urquizu, Edurne; Paratusic, Selma; Goyenechea, Júlia; Gómez-Canela, Cristian (International Journal of Molecular Sciences. 2024; 25(22):12248, 2024-11-14)
      The secondary neurotoxicity induced by severe organophosphorus (OP) poisoning, including paraoxon (POX), is associated with cognitive impairments in survivors, who, despite receiving appropriate emergency ...
    • Rational Method for Structural Simplification as Key Step in Hit Discovery: The Case of FGFR2 and IGF1R Dual Inhibitors 

      Torres-Urtizberea, Endika; Borrell, Jose I.; Puig de la Bellacasa, Raimon; Estrada-Tejedor, Roger (International Journal of Molecular Sciences 2025, 26(9), 2025-05)
      In the classic medicinal chemistry hit discovery procedure, large virtual libraries undergo different filtering and prediction steps until a small group of molecules is selected for their subsequent ...
    • Regional mobility and COVID-19 vaccine hesitancy: Evidence from China 

      Wanglu, Huaxin; Valerio Mendoza, Octasiano M.; Chen, Simiao; Geldsetzer, Pascal; Adam, Maya (Vaccine 2025, 58, 2025-06-11)
      China’s Zero-COVID Policy imposed stringent restrictions on citizens’ mobility to curb the spread of COVID-19. While effective in reducing viral transmission, these measures may have inadvertently delayed ...
    • Tool for Greener Tourism: Evaluating Environmental Impacts 

      Campos Herrero, Cristina; Dias, Ana; Gallego, María; Gutiérrez, David; Quinteiro, Paula; Villanueva-Rey, Pedro; Oliveira, Sara; Albertí, Jaume; Bala Gala, Alba; Fullana-i-Palmer, Pere; Fullana-Puig, Margalida; Melón, Lela; Sazdovski, Ilija ; Rodríguez Fernández-Arroyo, Eduardo; Roca, Mercè; Xifré, Ramon; Laso Cortabitarte, Jara; Margallo Blanco, María; ALDACO GARCIA, RUBEN (Sustainability 2025, 17(8), 2025-04)
      Travel and tourism are essential to global economies, generating social, economic, and environmental impacts. However, there is a lack of standardized methodologies to assess the environmental footprint ...
    • Unveiling the potential abuse liability of α-D2PV: A novel α-carbon phenyl-substituted synthetic cathinone 

      Nadal-Gratacós, Núria; Mata, Sandra; Puigseslloses, Pol; De Macedo, Morgane; Lardeux, Virginie; Pain, Stephanie; Wang, Fu-Hua; Källsten, Liselott; Pubill, David; Berzosa, Xavier; Kehr, Jan; Solinas, Marcello; Camarasa, Jordi; Escubedo, Elena; López-Arnau, Raúl (Neuropharmacology 2025, 272, 2025-07-01)
      Synthetic cathinones are emerging psychoactive substances designed to mimic the effects of classical psychostimulants. Among them, α-D2PV, a novel pyrrolidine-containing cathinone characterized by a ...
    • NIR Luminescence from Deep-Level Traps in CsPbBr3 Microcrystals 

      Vandenwijngaerden, Jonathan; Pradhan, Bapi; Van Hout, Bob; Fron, Eduard; Araki, Yasuyuki; Zhang, Xianjun; Shibata, Yutaka; Santantonio, Dario; Bresolí-Obach, Roger; Nonell, Santi; Yuan, Haifeng; Xu, Jialiang; Van der Auweraer, Mark; Roeffaers, Maarten; Hofkens, Johan; Fukumura, Hiroshi; Debroye, Elke (The Journal of Physical Chemistry Letters 2025, 16 (14), 2025-04-10)
      In this study, we report the first observation of a near-infrared (NIR) emission band from all-inorganic CsPbBr3 and CsPb(Br/Cl)3 perovskite microcrystals. By means of temperature- and power-dependent ...
    • Achieving red-light anticancer photodynamic therapy under hypoxia using Ir(iii)–COUPY conjugates 

      Ortega-Forte, Enrique; Rovira, Anna; Ashoo, Pezhman; Izquierdo García, Eduardo; Hally, Cormac; Abad-Montero, Diego; Jordà Redondo, Mireia; Vigueras Bautista, Gloria; Deyà, Alba; Hernández, José Luis; GALINO, JORGE; Bosch, Manel; Alberto, Marta Erminia; Francés-Monerris, Antonio; Nonell, Santi; Ruiz, Jose; Marchán, Vicente (Inorganic Chemistry Frontiers 2023, 12 (9), 2025-05-07)
      Despite the potential of photodynamic therapy (PDT), this oxygen-dependent oncological treatment is greatly restricted in the clinic by the well-known hypoxic feature of solid tumors. Here we provide ...
    • Functional Polarization of Liver Macrophages by Glyco Gold Nanoparticles 

      Fernandez Alarcon, Jennifer; Perez Schmidt, Patricia; Panini, Nicolò; Caruso, Francesca; Violatto, Martina Bruna; SUKUBO, NATHS GRAZIA; Martinez-Serra, Alberto; Ekalle Soppo, Charlotte Blanche ; Morelli, Annalisa; Moscatiello, Giulia Yuri; Grasselli, Chiara; Corbelli, Alessandro; Fiordaliso, Fabio; Kelk, Joe; PETROSILLI, LAURA; D'ORAZIO, GIUSEPPE; Mateu Ferrando, Ruth; Verdaguer, Ariadna; Fornaguera, Cristina; LAY, LUIGI; Fumagalli, Stefano; RECCHIA, SANDRO; Monopoli, Marco P.; Bigini, Paolo; Sitia, Giovanni (Advanced Science 2025, 12 (16), 2025-04-24)
      Macrophages are crucial drivers of innate immunity. Reprogramming macrophages to a restorative phenotype in cancer or autoimmune diseases can stop their cancer-promoting activity or trigger anti-inflammatory ...
    • Long-time behaviour of the correlated random walk system 

      Menacho, Joaquin; Pellicer , Marta; Solà-Morales Rubió, Joan (Evolution Equations and Control Theory, 2025, 14(4), 2025-08)
      In this work, we consider the so-called correlated random walk system (also known as correlated motion or persistent motion system), used in biological modelling, among other fields, such as chromatography. ...
    • New Trends in Brain Shuttle Peptides 

      Prades, Roger; Teixidó, Meritxell; Oller-Salvia, Benjamí (Molecular Pharmaceutics 2025, 22, 3, 1100–1109, 2025-03-03)
      The pharmacological treatment of central nervous system diseases faces significant challenges due to the presence of the blood–brain barrier (BBB). This barrier naturally protects the brain and prevents ...
    • The first look: a biometric analysis of emotion recognition using key facial features 

      Gonzalez-Acosta, Ana M. S.; Vargas Treviño, Marciano; Batres-Mendoza, Patricia; Guerra-Hernandez, Erick Israel; Gutierrez Gutierrez, Jaime C.; Cano Perez, Jose L.; Solis Arrazola, Manuel Alejandro; Rostro Gonzalez, Horacio (Frontiers in Computer Science 2025, 7, 2025)
      Introduction: Facial expressions play a crucial role in human emotion recognition and social interaction. Prior research has highlighted the significance of the eyes and mouth in identifying emotions; ...
    • Optimization of 3D printing conditions for BaCe0.6Zr0.3Y0.1O3-δ in the construction of amperometric high-temperature H2 sensors 

      Hinojo, Antonio; Lujan, Enric; Colominas, Sergi; Abella, Jordi (Talanta Open 2025, 11, 2025-08)
      Proton-conducting ceramics, particularly BaCe0.6Zr0.3Y0.1O3-δ (BCZY), are promising materials for hydrogen energy applications. However, traditional fabrication methods are limited in their ability to ...
    • Optimizing Reservoir Separability in Liquid State Machines for Spatio-Temporal Classification in Neuromorphic Hardware 

      Alvarez Canchila, Oscar Ivan; Espinal, Andres; Patiño Saucedo, Alberto; Rostro Gonzalez, Horacio (Journal of Low Power Electronics and Applications 2025, 15(1), 4, 2025-03)
      In this paper, we propose an optimization approach using Particle Swarm Optimization (PSO) to enhance reservoir separability in Liquid State Machines (LSMs) for spatio-temporal classification in ...
    • An antibody-photosensitiser bioconjugate overcomes trastuzumab resistance in HER2-positive breast cancer 

      Jordà Redondo, Mireia; Piqueras, Ana; Castillo, Ana; Fernandez, Pedro Luis; Bresolí Obach, Roger; Blay, Lidia; Julian Ibañez, Joan Francesc; Nonell, Santi (European Journal of Medicinal Chemistry 2025, 290, 2025-06-05)
      HER2-positive breast cancer, characterized by the overexpression of HER2 receptors, often develops resistance to trastuzumab, limiting its therapeutic efficacy. In this study, we explore the use of ...
    • The interplay of author and editor gender in acceptance delays: evidence from accounting journals 

      Argilés Bosch, Josep M.; Kasperskaya, Yuliya; Garcia-Blandon, Josep; Ravenda, Diego (Scientometrics 2025, 130, 2025-03)
      The objective of this study is to examine the impact of the gender of editors and authors, as well as their interaction, on acceptance delays (ACCDEL) of articles. We focus on genders of the corresponding ...
    • Thermophysical Characterization of Sustainable Pathways for Hydrofluorocarbons Separation Utilizing Deep Eutectic Solvents 

      Alencar, L.V.T.D.; González Barramuño, Bastián; Rodriguez Reartes, S.B.; Quinteros-Lama, Héctor; Garrido, J.M.; Codera, Victoria; Pou, Josep Oriol; Tavares, Frederico; González Olmos, Rafael; Llovell Ferret, Félix Lluís (Journal of Industrial and Engineering Chemistry 2025, 146, 2025-06-25)
      The widespread use of hydrofluorocarbons (HFCs) in refrigeration ushered in a significant environmental challenge due to their high global warming potential. Effective recovery and separation techniques ...
    • A POCIS-based approach for the monitoring of pharmaceuticals in wastewater treatment plants: Calibration and deployment challenges 

      Domínguez García, Pol; Ortiz Almirall, Xavier; Gómez-Canela, Cristian (Environmental Pollution 2025, 367, 2025-02-15)
      The impact of pharmaceuticals in aquatic environments requires complementary monitoring techniques to the more conventional grab sampling approach for an improved sample representativity. This study ...
    • CEO demographics and gender diversity in senior management in large Scandinavian firms 

      Garcia-Blandon, Josep; Argilés Bosch, Josep M.; Ravenda, Diego (Gender in Management. 2024;39(1):1-17, 2024-01-23)
      Purpose This study aims to investigate whether chief executive officer (CEO) demographics are associated with gender diversity in senior management in the Scandinavia region. Design/methodology/ap ...
    • Development of Electrochemical and Colorimetric Biosensors for Detection of Dopamine 

      Khan, Rimsha; Anjum, Saima; Fatima, Nishat; Farooq, Nosheen; Shaheen, Aqeela; Fernandez Garcia, Javier; Khan, Muhammad Imran; Shanableh, Abdallah (Chemosensors. 2024;12(7):126, 2024-07-03)
      Neurotransmitters are essential chemical messengers required for proper brain function, and any changes in their concentrations can lead to neuronal diseases. Therefore, sensitive and selective detection ...
    • Synergistic Effect of NiAl-Layered Double Hydroxide and Cu-MOF for the Enhanced Photocatalytic Degradation of Methyl Orange and Antibacterial Properties 

      Batool, Iqra; Aroob, Sadia; Anwar, Farheen; Taj, Muhammad Babar; Baamer, Doaa F.; Almasoudi, Afaf; Ali, Omar Makram; Aldahiri, Reema H.; Alsulami, Fatimah Mohammad H.; Khan, Muhammad Imran; Fernandez Garcia, Javier (Catalysts. 2024;14(10):719, 2024-10-15)
      This study synthesized NiAl-layered double hydroxide (LDH)/Cu-MOF photocatalyst using a simple impregnation method involving NiAl-LDH and Cu-MOF. The successful synthesis was confirmed through Fourier ...