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PET Imaging of Self-Assembled 18F-Labelled Pd2L4 Metallacages for Anticancer Drug Delivery

dc.contributorUniversitat Ramon Llull. IQS
dc.contributor.authorCosialls, Raúl
dc.contributor.authorSimó, Cristina
dc.contributor.authorBorrós i Gómez, Salvador
dc.contributor.authorGómez Vallejo, Vanessa
dc.contributor.authorSchmidt, Claudia
dc.contributor.authorLlop, Jordi
dc.contributor.authorCuenca, Ana B.
dc.contributor.authorCasini, Angela
dc.date.accessioned2025-01-09T19:07:36Z
dc.date.available2025-01-09T19:07:36Z
dc.date.issued2023-01-12
dc.identifier.issn1521-3765ca
dc.identifier.urihttp://hdl.handle.net/20.500.14342/4695
dc.description.abstractTo advance the design of self-assembled metallosupramolecular architectures as new generation theranostic agents, the synthesis of 18F-labelled [Pd2L4]4+ metallacages is reported. Different spectroscopic and bio-analytical methods support the formation of the host-guest cage-cisplatin complex. The biodistribution profiles of one of the cages, alone or encapsulating cisplatin have been studied by PET/CT imaging in healthy mice in vivo, in combination to ICP-MS ex vivo.ca
dc.format.extentp.7ca
dc.language.isoengca
dc.publisherWileyca
dc.relation.ispartofChemistry – A European Journal 2023, 29(3), e202202604ca
dc.rights© L'autor/aca
dc.rightsAttribution 4.0 Internationalca
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subject.otherAmmonium trifluoroboratesca
dc.subject.otherCisplatinca
dc.subject.otherDrug deliveryca
dc.subject.otherMetallacagesca
dc.subject.otherPET imagingca
dc.subject.otherSelf-assemblyca
dc.subject.otherAmonica
dc.subject.otherCisplatíca
dc.subject.otherMedicaments--Modes d'administracióca
dc.titlePET Imaging of Self-Assembled 18F-Labelled Pd2L4 Metallacages for Anticancer Drug Deliveryca
dc.typeinfo:eu-repo/semantics/articleca
dc.rights.accessLevelinfo:eu-repo/semantics/openAccess
dc.embargo.termscapca
dc.subject.udc54ca
dc.subject.udc577ca
dc.identifier.doihttps://doi.org/10.1002/chem.202202604ca
dc.relation.projectIDinfo:eu-repo/grantAgreement/MCI/PN I+D/PID2020-113661GB-I00ca
dc.relation.projectIDinfo:eu-repo/grantAgreement/SUR del DEC/SGR/2017 SGR 01051ca
dc.relation.projectIDinfo:eu-repo/grantAgreement/SUR del DEC/SGR/2017 SGR 00294ca
dc.relation.projectIDinfo:eu-repo/grantAgreement/MCI/PN I+D/PID2020-117656RB-I00ca
dc.description.versioninfo:eu-repo/semantics/publishedVersionca


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