Visualitzant Articles publicats en revistes per títol
Ara mostrant els elements 226-245 de 256
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Targeting transthyretin in Alzheimer's disease: Drug discovery of small-molecule chaperones as disease-modifying drug candidates for Alzheimer's disease
(European Journal of Medicinal Chemistry, 2021-12-15)Transthyretin (TTR) has a well-established role in neuroprotection in Alzheimer's Disease (AD). We have setup a drug discovery program of small-molecule compounds that act as chaperones enhancing ... -
Teaching Cheminformatics through a Collaborative Intercollegiate Online Chemistry Course (OLCC)
(Journal of Chemical Education, 2020-12-21)While cheminformatics skills necessary for dealing with an ever-increasing amount of chemical information are considered important for students pursuing STEM careers in the age of big data, many schools ... -
Tetramethylbenzidine: an acoustogenic photoacoustic probe for reactive oxygen species detection
(Sensors. Vol.20, n.20 (2020), 5952, 2020-10)Photoacoustic imaging is attracting a great deal of interest owing to its distinct advantages over other imaging techniques such as fluorescence or magnetic resonance image. The availability of photoacoustic ... -
The anthropological function of dialogue in political reconciliation processes: ethical analysis of Ignacio Ellacuría's thought on the 25th anniversary of his death (1989-2014)
(Ramon Llull Journal of Applied Ethics, Núm. 5 (2014), p.125-141, 2014)The idea of a just and lasting peace seems to be unachievable when people are suffering a civil or international war, a violent revolutionary process or a dictatorship, or when they are immersed in a ... -
The external didactic transposition of mathematics at university level: dilemmas and challenges
(Educaçao Matemática Pesquisa. Vol.22, n.4 (2020) p.373-386, 2020)We develop the idea that research on university mathematics education needs to more systematically address the external didactic transposition. After outlining existing research that goes more or less ... -
The impact of the perceived risk of COVID-19 on consumers' attitude and behavior toward locally produced food
(British Food Journal, 2021-12-17)Purpose This study analyzes the impact of the COVID-19 pandemic on the consumption of locally produced food. In particular, it examines an extended model of the theory of planned behavior, with the ... -
The influence of the trade-off between profitability and future increases in sales on cost stickiness
(Estudios de Economía. Vol. 44, No.1 (2017), pág. 81-104, 2017-06)This study analyses cost stickiness under the dilemma between current profitability and future sales increase. When activity decreases firms are faced to keep profitability adjusting resources, while ... -
The interaction effects of firm and partner tenure on audit quality
(Accounting and Business Research. Vol.47, n.7 (2017), p.810-830, 2017-02)This paper investigates the impact of firm and partner tenure on audit quality, where audit quality is proxied by discretionary accruals. We study a sample of Spanish listed companies between 2005 and ... -
The Masking Game: Design of Activatable Antibodies and Mimetics for Selective Therapeutics and Cell Control
(ACS Central Science, 2021-04-26)The high selectivity and affinity of antibody binding havemade antibodies all-pervasive tools in therapy, diagnosis, and basic science.A plethora of chemogenetic approaches has been devised to makeantibodies ... -
The potential of proteolytic chimeras as pharmalogical tools and therapeutic agents
(Molecules. Vol.25, n.24 (2020), 5956, 2020-12)The induction of protein degradation in a highly selective and efficient way by means of druggable molecules is known as targeted protein degradation (TPD). TPD emerged in the literature as a revolutionary ... -
The role of carbon black surface activity and specific surface area in the vulcanization reaction
(Afinidad. Vol.59, n.500 (2002), p.337-342, 2002)This paper reviews the work developed in studying how Carbon Black presence may affect the vulcanization process and the mechanisms by which CB and polymer interact, which has not been completely described ... -
The sequential action of MIDA9/PP2C.D1, PP2C.D2, and PP2C.D5 is necessary to form and maintain the hook after germination in the dark
(Frontiers in Plant Science, 2021-03-09)During seedling etiolation after germination in the dark, seedlings have closed cotyledons and form an apical hook to protect the meristem as they break through the soil to reach the surface. Once in ... -
The Sixth Merger Wave and Wealth Effects of M&A Announcements: An Analysis of Large European Bidding Companies
(European Accounting and Management Review, 2017-12-06)This study aims to investigate short-term market reaction, including stock returns, volatility, and trading volumes of bidder firms, around the announcement dates of relevant merger and acquisition (M&A) ... -
Therapeutic potential of N-acetylcysteine in acrylamide acute neurotoxicity in adult zebrafish
(Scientific Reports. Vol.9, n.1 (2019), 16467, 2019-11)Two essential key events in acrylamide (ACR) acute neurotoxicity are the formation of adducts with nucleophilic sulfhydryl groups on cysteine residues of selected proteins in the synaptic terminals and ... -
Three-dimensional tumor-stroma co-culture system development using self-assembling peptide scaffolds
(Afinidad. Vol.76, n.587 (2019), p.163-170, 2019-07)Cancer research has traditionally relied on 2D cell culture, focusing mainly on cancer cells and its disrupted genetics. However, tumors have been accepted as complex tissues, and as such, they need ... -
THz‐conductivity of CVD graphene on different substrates
(Physica Status Solidi (B). Vol. 252, no.11 (2015), p.2423-2428, 2015-11)Optoelectronic properties of CVD graphene are characterized over a wide frequency range: THz, IR, visible, and near‐UV. We used Raman spectroscopy to characterize the synthesized graphene films. All ... -
Time-dependent mechanical properties in polyetherimide 3D-Printed parts are dictated by isotropic performance being accurately predicted by the generalized time hardening model
(Molecules. Vol.12, n.3 (2020), 678, 2020-03)The Fused-Deposition Modelling (FDM) technique has transformed the manufacturing discipline by simplifying operational processes and costs associated with conventional technologies, with polymeric ... -
Tracking the behavior of players in a cost accounting simulation and identifying work patterns
(Procedia - Social and Behavioral Sciences Vol.182 (2015), p.203-212, 2015-05-13)This paper summarizes the results of using two Excel-based simulations run on a cost accounting course to instruct about the contribution margin. Students’ learning has been assessed using achievement ... -
Tracking the behavior of players in a finance simulation and identifying work patterns
(Procedia - Social and Behavioral Sciences vol.182 (2015) p.197 – 202, 2015-05-13)This paper summarizes the results of using an Excel-based simulation run on a finance course. The activity intends to instruct the students that firms with a negative cash cycle and with negative working ... -
Transglycosylation Activity of Engineered Bifidobacterium Lacto-N-Biosidase Mutants at Donor Subsites for Lacto-N-Tetraose Synthesis
(International Journal of Molecular Sciences, 2021-03-21)The health benefits of human milk oligosaccharides (HMOs) make them attractive targets as supplements for infant formula milks. However, HMO synthesis is still challenging and only two HMOs have been ...