IQS: Envíos recientes
Mostrando ítems 261-280 de 639
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Bacteriophobic Zwitterionic/Dopamine Coatings for Medical Elastomers
(Advanced Materials Interfaces, 2022, 9(30), 2201152, 2022)Despite modern advancements in sterilization and medical practices, bacterial infections remain a significant concern in the implantation of medical devices. There is currently an urgent need for ... -
BBX16 mediates the repression of seedling photomorphogenesis downstream of the GUN1/GLK1 module during retrograde signalling
(New Phytologist 2022, 234(1), 93-106, 2022)Plastid-to-nucleus retrograde signalling (RS) initiated by dysfunctional chloroplasts impact photomorphogenic development. We have previously shown that the transcription factor GLK1 acts downstream of ... -
Behavioural and neurochemical effects after repeated administration of N-ethylpentylone (ephylone) in mice
(Journal of Neurochemistry, 2022, 160(2), 218-233, 2022)N-ethyl-pentylone (NEP), also known as ‘ephylone’ and N-ethylnorpentylone, has been identified as one of the most recent novel psychostimulants to emerge into the illicit drug market and it has been ... -
3,4-Methylenedioxy methamphetamine, synthetic cathinones and psychedelics: From recreational to novel psychotherapeutic drugs
(Frontiers in Psychiatry, 2022)The utility of classical drugs used to treat psychiatric disorders (e.g., antidepressants, anxiolytics) is often limited by issues of lack of efficacy, delayed onset of action or side effects. Psychoactive ... -
Long term outcomes of biomaterial-mediated repair of focal cartilage defects in a large animal model
(European Cells & Materials Journal, 2021-01-07)The repair of focal cartilage defects remains one of the foremost issues in the field of orthopaedics. Chondral defects may arise from a variety of joint pathologies and left untreated, will likely ... -
Entrapped Transient Chloroform Solvates of Bilastine
(Crystals, 2021-03-28)The knowledge about the solid forms landscape of Bilastine (BL) has been extended. The crystal structures of two anhydrous forms have been determined, and the relative thermodynamic stability among the ... -
Re-purposing tourism: engaging our radical in tourism education
(Journal of Teaching in Travel & Tourism, 2022-02-06) -
QUICKSERV: a service quality assessment tool for the quick-service restaurant industry
(British Food Journal, 2021-07-17)Purpose The purpose of this study is to empirically develop and validate a practical, consistent and specific scale to assess perceived service quality at the service encounter at quick-service restaurants ... -
Cómo generar clientes satisfechos en empresas de servicios en un entorno multicanal. El caso de la gestión de marketing de un programa universitario
(Boletín de Estudios Económicos, 2015-08)Los servicios son ofertas intangibles cuya calidad es difícil de valorar por parte del usuario. En este artículo revisaremos los conceptos clave del marketing de servicios. Así, describiremos las ... -
Engineered microtissues for the bystander therapy against cancer
(Materials Science and Engineering C, 2021-01-13)Thymidine kinase expressing human adipose mesenchymal stem cells (TK-hAMSCs) in combination with ganciclovir (GCV) are an effective platform for antitumor bystander therapy in mice models. However, this ... -
CRISPR/Cas9-Mediated Knockin Application in Cell Therapy: A Non-viral Procedure for Bystander Treatment of Glioma in Mice
(Molecular Therapy: Nucleic Acids, 2017-07-26)The use of non-viral procedures, together with CRISPR/Cas9 genome-editing technology, allows the insertion of single-copy therapeutic genes at pre-determined genomic sites, overcoming safety limitations ... -
Comprehensive Characterization of 76 Pharmaceuticals and Metabolites in Wastewater by LC-MS/MS
(Chemosensors, 2021-09-24)Wastewaters are considered one of the main sources of pollution in the aquatic environment as release a large number of contaminants every day. Emerging contaminants such as pharmaceuticals have special ... -
The Effect of the Expression of the Antiapoptotic BHRF1 Gene on the Metabolic Behavior of a Hybridoma Cell Line
(Applied Sciences, 2021-07-06)One of the most important limitations of mammalian cells-based bioprocesses, and particularly hybridoma cell lines, is the accelerated metabolism related to glucose and glutamine consumption. The high ... -
Specially designed polyaniline/polypyrrole ink for a fully printed highly sensitive pH microsensor
(ACS Applied Materials & Interfaces, 2021-07-06)pH sensing for healthcare applications requires sensors with mechanically stable materials of high sensitivity and high reproducibility combined with low-cost fabrication technologies. This work proposes ... -
Exploring the gendered tourism entrepreneurial ecosystem in Barcelona and responses required: a feminist ethic of care
(Journal of Sustainable Tourism, 2023-05-08)Barcelona is an attractive location in Spain for tourism entrepreneurship; however, women are significantly under-represented. This study adopts a locally based perspective and a feminist ethic of care ... -
Short-term exposure to environmental levels of nicotine and cotinine impairs visual motor response in zebrafish larvae through a similar mode of action: Exploring the potential role of zebrafish α7 nAChR
(Science of the Total Environment, 2023-12-14)The current view is that environmental levels of nicotine and cotinine, commonly in the ng/L range, are safe for aquatic organisms. In this study, 7 days post-fertilization zebrafish embryos have been ... -
From dysbiosis to neuropathologies: Toxic effects of glyphosate in zebrafish
(Ecotoxicology and Environmental Safety, 2023-12-26)Glyphosate, a globally prevalent herbicide known for its selective inhibition of the shikimate pathway in plants, is now implicated in physiological effects on humans and animals, probably due to its ... -
Daphnia magna an emerging environmental model of neuro and cardiotoxicity of illicit drugs
(Environmental Pollution, 2024-02-14)Cocaine, methamphetamine, ectasy (3,4-methylenedioxy amphetamine (MDMA)) and ketamine are among the most consumed drugs worldwide causing cognitive, oxidative stress and cardiovascular problems in humans. ... -
Phototactic behaviour and neurotransmitter profiles in two Daphnia magna clones: Vertical and horizontal responses to fish kairomones and psychotropic drugs
(Science of The Total Environment, 2022-03-18)Animal behavioural responses are increasingly being used in environmental risk assessment. Nevertheless, behavioural responses are still hampered by a lack of standardisation. Phototactic behaviour in ... -
A Zebrafish Model of Neurotoxicity by Binge-Like Methamphetamine Exposure
(Frontiers in Pharmacology, 2021-11-22)Hyperthermia is a common confounding factor for assessing the neurotoxic effects of methamphetamine (METH) in mammalian models. The development of new models of methamphetamine neurotoxicity using ...