Mostrando ítems 201-220 de 639

    • Measuring the provincial supply of higher education institutions in China 

      Borsi, Mihály Tamás; Valerio, Octasiano; Comim, Flavio (China Economic Review 2022, 71, 101724, 2022-02)
      This paper proposes and estimates three novel higher education indices for 31 Chinese provinces: i) the Chinese Higher Education Density Index (CHEDI) to analyze the evolution of the quantitative ...
    • Measuring the sustainable development goals: A poset analysis 

      Tadashi, Hirai; Comim, Flavio (Ecological Indicators 2022, 145, 109605, 2022-12)
      Sustainability requires balanced development. The economy, society and the environment all need to be pursued simultaneously. In this context, the issue of incomparabilities among different dimensions ...
    • Recent advances in the pharmacological targeting of ubiquitin-regulating enzymes in cancer 

      Montagut, Ana Maria; Armengol, Marc; Gorjón de Pablo, Gema; Estrada Tejedor, Roger; Borrell Bilbao, José Ignacio; Roué, Gaël (Seminars in Cell & Developmental Biology 2022, 132, 213-229, 2022-12)
      As a post-translational modification that has pivotal roles in protein degradation, ubiquitination ensures that intracellular proteins act in a precise spatial and temporal manner to regulate diversified ...
    • Analysis of laccase‐like enzymes secreted by fungi isolatedfrom a cave in northern Spain 

      Fernández Remacha, Daniel; González Riancho, Candela; Lastra Osua, Miranda; González Arce, Aránzazu; Montánchez, Itxaso; García Lobo, Juan María; Estrada Tejedor, Roger; Kaberdin, Vladimir R. (Microbiology Open 2022, 11(2), e1279, 2022-04)
      Laccases belong to a family of multicopper enzymes able to oxidize a broad spectrum of organic compounds. Despite the well-known property of laccases to carry out bleaching and degradation of industrial ...
    • Mechanical performance of additively manufactured lightweight cellular solids: Influence of cell pattern and relative density on the printing time and compression behavior 

      Forés-Garriga, Albert; Gómez Gras, Giovanni; Pérez Martínez, M. (Marco) (Materials & Design Volume 2022, 215, 110474, 2022-03)
      A comprehensive investigation is presented on the Fused Filament Fabrication (FFF) technology’s possibilities to create cellular solids with a broad spectrum of specific stiffness and strength, modifying ...
    • Model food soils for investigating cleaning: A review 

      Gottschalk, Nathalie; Augustin, Wolfgang; Scholl, Stephan; Wilson, Ian; Mercadé Prieto, Rubén (Food and Bioproducts Processing 2022, 136, 249-296, 2022-11)
      Cleaning operations are performed regularly throughout the food industry. This review focuses on the removal of strongly adherent fouling deposits which compromise the performance and hygienic status ...
    • Mutated RAS-associating proteins and ERK activation in relapse/refractory diffuse large B cell lymphoma 

      Benoit, Alexandre; Bou Petit, Elisabeth; Chou, Hsiang; Lu, Melissa; Guilbert, Cynthia; Mingyi Luo, Vincent; Assouline, Sarit; Morin, Ryan D; Dmitrienko, Svetlana; Estrada Tejedor, Roger; Johnson, Nathalie A.; Mann, Koren K. (Scientific Reports 2022, 12, 779, 2022)
      Diffuse large B cell lymphoma (DLBCL) is successfully treated with combination immuno-chemotherapy, but relapse with resistant disease occurs in ~ 40% of patients. However, little is known regarding ...
    • Neuropsychopharmacology of Emerging Drugs of Abuse: meta- and para-Halogen-Ring-Substituted α-PVP (“flakka”) Derivatives 

      Nadal Gratacós, Núria; Lleixà, Esther; Gibert Serramià, Mónica; Estrada Tejedor, Roger; Berzosa Rodríguez, Xavier; Batllori Aguilà, Xavier; Pubill, David; Camarasa, Jordi; Fonseca, David; López-Arnau, Raúl (International Journal of Molecular Sciences 2022, 23(4), 2226, 2022-02)
      Changes in the molecular structure of synthetic cathinones has led to an increase in the number of novel emerging drugs in the illicit drug market at an unprecedented rate. Unfortunately, little is known ...
    • Overcoming Paradoxical Kinase Priming by a Novel MNK1 Inhibitor 

      Bou Petit, Elisabeth; Hümmer, Stefan; Alarcon, Helena; Slobodnyuk, Konstantin; Cano Galietero, Marta; Fuentes, Pedro; Guijarro, Pedro J.; Muñoz, María José; Suarez Cabrera, Leticia; Santamaria, Anna; Estrada Tejedor, Roger; Borrell Bilbao, José Ignacio; Ramón y Cajal, Santiago (Journal of Medicinal Chemistry, 2022, 65(8), 6070-6087, 2022-04-28)
      Targeting the kinases MNK1 and MNK2 has emerged as a valuable strategy in oncology. However, most of the advanced inhibitors are acting in an adenosine triphosphate (ATP)-competitive mode, precluding ...
    • Photosensitive EGFR-Targeted Nanocarriers for Combined Photodynamic and Local Chemotherapy 

      de las Heras, Elena; Sagristá, M. Lluïsa; Agut Bonsfills, Montserrat; Nonell, Santi (Pharmaceutics 2022, 14(2), 405, 2022-02)
      The major limitation of any cancer therapy lies in the difficulty of precisely controlling the localization of the drug in the tumor cells. To improve this drawback, our study explores the use of ...
    • Plasma-induced nanostructured metallic silver surfaces: study of bacteriophobic effect to avoid bacterial adhesion on medical devices 

      García Bonillo, Cristina; Texidó, Robert; Gilabert-Porres, Joan; Borrós i Gómez, Salvador (Heliyon, 2022, 8(10), e10842, 2022-10)
      Biofilm formation in medical devices represents one of the major problems for the healthcare system, especially those that occur on implantable silicone-based devices. To provide a general solution to ...
    • Repeated administration of N-ethyl-pentedrone induces increased aggression and impairs social exploration after withdrawal in mice 

      Espinosa Velasco, María; Reguilón, Marina D.; Bellot, Marina; Nadal Gratacós, Núria; Berzosa Rodríguez, Xavier; Gómez Canela, Cristian; Rodríguez Arias, Marta; Camarasa, Jordi; Fonseca, David; Pubill, David; López-Arnau, Raúl (Progress in Neuro-Psychopharmacology and Biological Psychiatry 2022, 117, 110562, 2022-07)
      N-ethyl-pentedrone (NEPD, 2-(ethylamino)-1-phenyl-1-pentanone) is one of the latest synthetic cathinone derivatives that emerged into the illicit drug market. This drug has psychostimulant properties ...
    • Riboflavin-binding proteins for singlet oxygen production 

      Lafaye, Céline; Aumonier, Sylvain; Torra, Joaquim; Signor, Luca; von Stetten, David; Noirclerc Savoye, Marjolaine; Shu, Xiaokun; Ruiz González, Rubén; Gotthard, Guillaume; Royant, Antoine; Nonell, Santi (Photochemical & Photobiological Sciences 2022, 21, 1545–1555, 2022)
      miniSOG, developed as the first fully genetically encoded singlet oxygen photosensitiser, has found various applications in cell imaging and functional studies. Yet, miniSOG has suboptimal properties, ...
    • Selective dissolution of polysulfone support material of fused filament fabricated Ultem 9085 parts 

      Chueca de Bruijn, Ariadna; Gómez Gras, Giovanni; Pérez Martínez, M. (Marco) (Polymer Testing 2022, 108, 107495, 2022-04)
      One of the main advantages of 3D printing lies in the fact that the desired object is constructed layer by layer, enabling the production of complex geometries otherwise unfeasible with conventional ...
    • SPEEK and SPPO Blended Membranes for Proton Exchange Membrane Fuel Cells 

      Khan, Muhammad Imran; Shanableh, Abdallah; Shahida, Shabnam; Lashari, Mushtaq Hussain; Manzoor, Suryyia; Fernandez Garcia, Javier (Membranes 2022, 12(3), 263, 2022-03)
      In fuel cell applications, the proton exchange membrane (PEM) is the major component where the balance among dimensional stability, proton conductivity, and durability is a long-term trail. In this ...
    • Study of the Sloshing Dynamics in Partially Filled Rectangular Tanks with Submerged Baffles Using VOF and LES Turbulence Methods for Different Impact Angles 

      Vallés Rebollo, Xavier; Sadeghi, Ehsan; Kusano, Ibuki; García Granada, Andrés-Amador (Computation 2022, 10(12), 225, 2022-12)
      This research studies how the angle and dimensions of a single baffle affect the dynamics of a fluid in a closed rectangular tank under an accelerated harmonic vibration in resonance. A half-filled ...
    • Sustainability and Human Development Indicators: A Poset Analysis 

      Comim, Flavio; Tadashi, Hirai (Ecological Economics 2022, 198, 107470, 2022-08)
      The paper introduces the methodology of partially ordered sets to evaluate sustainable human development indicators. It shows its importance to the integration of human and environmental indicators, ...
    • Sustainability Assessment of the Utilization of CO2 in a Dielectric Barrier Discharge Reactor Powered by Photovoltaic Energy 

      Pou Ibar, Josep Oriol, 1980-; Estopañán, Eduard; Fernandez Garcia, Javier; González Olmos, Rafael (Processes 2022, 10(9), 1851, 2022-09)
      The direct activation of diluted CO2 in argon was studied in a co-axial dielectric barrier discharge (DBD) reactor powered by photovoltaic energy. The influence of the initial CO2 and argon concentration ...
    • Switchable Electrostatically Templated Polymerization 

      Li, Chendan; Magana Rodríguez, Jose Rodrigo; Sobotta, Fabian; Wang, Junyou; Cohen Stuart, Martien; van Ravensteijn, Bas; Voets, Ilja (Angewandte Chemie International Edition 2022, 61(39), e202206780, 2022-09-26)
      We report a switchable, templated polymerization system where the strength of the templating effect can be modulated by solution pH and/or ionic strength. The responsiveness to these cues is incorporated ...
    • The evolution of a study and research path in Statistics 

      Markulin, Kristina; Bosch, Marianna; Florensa, Ignasi; Montañola i Sales, Cristina (EpiDEMES 2022, 1, 7584, 2022)
      We present the organisation of a first course in statistics for Business Administration degree students, which includes a study and research path (SRP) as an inquiry-based teaching proposal. The paper ...