IQS: Recent submissions
Now showing items 221-240 of 736
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Numerical and experimental study to predict the forming process conditions of non‑axisymmetric glass perfume bottles
(The International Journal of Advanced Manufacturing Technology 2023, 126, 735-748, 2023-05)Blow and blow forming process for glass bottle is already validated for 2D axisymmetrical bottles. Current research evaluates the capabilities of the 3D simulations with more complex geometries. This ... -
A tailored decomposition approach for optimization under uncertainty of carbon removal technologies in the EU power system
(Computers & Chemical Engineering. 2024;187, August :108691, 2024-05-22)The broad portfolio of negative emissions technologies calls for integrated analyses to explore the synergies between them and the power sector, with which they display strong links. These analyses ... -
Expanding the chitin oligosaccharide portfolio by engineering NodC chitin synthases in Escherichia coli
(Current Research in Biotechnology. 2024;8:100255, 2024-09-17)Synthetic biology greatly accelerated the building process of potential microbial cell factories for the production of industrially relevant compounds, e.g., chitooligosaccharides (COS) which have an ... -
Unravelling the role of individual components in pBAE/polynucleotide polyplexes in the synthesis of tailored carriers for specific applications: on the road to rational formulations
(Nanoscale Advances 2023, 7 (6), 2023-03)Oligopeptide end–modified poly(β-amino ester)s (OM-pBAEs) offer a means for the effective implementation of gene therapeutics in the near future. A fine-tuning of OM-pBAEs to meet application requirements ... -
Thermodynamic Characterization of Gas Mixtures for Non-Thermal Plasma CO2 Conversion Applications with Soft-SAFT
(Journal of Chemical & Engineering Data 2023, 68, 1376-1387, 2023-06-08)Carbon dioxide (CO2) transformation into added-value products through non-thermal plasma (NTP) represents a novel technology of interest. The process involves, apart from CO2, mixtures of different gases ... -
Neuronal Prosurvival Role of Ceramide Synthase 2 by Olidogendrocyte-to-Neuron Extracellular Vesicle Transfer
(International Journal of Molecular Sciences 2023, 24(6), 5986, 2023-03)Ageing is associated with notorious alterations in neurons, i.e., in gene expression, mitochondrial function, membrane degradation or intercellular communication. However, neurons live for the entire ... -
In Vitro Antibacterial Activity of Silver Nanoparticles Conjugated with Amikacin and Combined with Hyperthermia against Drug-Resistant and Biofilm-Producing Strains
(Microbiology Spectrum 2023, 11 (3), 2023-06)In view of the current increase and spread of antimicrobial resistance (AMR), there is an urgent need to find new strategies to combat it. This study had two aims. First, we synthesized highly monodispersed ... -
Mitochondria-Targeted COUPY Photocages: Synthesis and Visible-Light Photoactivation in Living Cells
(The Journal of Organic Chemistry 2023, 88, 7128-7140, 2023-06-02)Releasing bioactive molecules in specific subcellular locations from the corresponding caged precursors offers great potential in photopharmacology, especially when using biologically compatible visible ... -
NanoFN10: A High-Contrast Turn-On Fluorescence Nanoprobe for Multiphoton Singlet Oxygen Imaging
(Sensors 2023, 23(10), 4603, 2023-05)An “off-on” fluorescent nanoprobe for near-infrared multiphoton imaging of singlet oxygen has been developed. The nanoprobe comprises a naphthoxazole fluorescent unit and a singlet-oxygen-sensitive furan ... -
De-Novo Design of pre-miR-21 Maturation Inhibitors: Synthesis and Activity Assessment
(Chemistry - A European Journal 2023, 29(40),e202300825, 2023-07-14)Targeting RNA with small molecules is a major challenge of current medicinal chemistry, and the identification and design of original scaffolds able to selectively interact with an RNA target remains ... -
Biomineralization in Three-Dimensional Scaffolds Based on Bacterial Nanocellulose for Bone Tissue Engineering: Feature Characterization and Stem Cell Differentiation
(Polymers 2023, 15(9), 2012, 2023-05)Bacterial nanocellulose (BNC) has a negative surface charge in physiological environments, which allows the adsorption of calcium ions to initiate the nucleation of different calcium phosphate phases. ... -
Poly(β-amino ester)s-Based Delivery Systems for Targeted Transdermal Vaccination
(Pharmaceutics 2023, 15(4), 1262, 2023-04)Nucleic acid vaccines have become a transformative technology to fight emerging infectious diseases and cancer. Delivery of such via the transdermal route could boost their efficacy given the complex ... -
Cognitive decline in diabetic mice predisposed to Alzheimer’s disease is greater than in wild type
(Life Science Alliance 2023, 6 (6), e202201789, 2023-06)In this work, we tested the hypothesis that the development of dementia in individuals with type 2 diabetes (T2DM) requires a genetic background of predisposition to neurodegenerative disease. As a proof ... -
Optimization of 3D autologous chondrocyte-seeded polyglycolic acid scaffolds to mimic human ear cartilage
(Biomaterials Science 2023, 13 (10), 2023-05)Auricular reconstruction in children with microtia is one of the more complex procedures in plastic surgery. Obtaining sufficient native material to build an ear requires harvesting large fragments of ... -
Overview of the current situation relating to chemical engineering degree courses
(Education for Chemical Engineers 2023, 43, 2023-04)In 2020, the Conference of Chemical Engineering Directors and Deans (CODDIQ) proposed the creation of an observatory to monitor chemical engineering degrees in Spain. This representative radiography of ... -
Nucleic acid-loaded poly(beta-aminoester) nanoparticles for cancer nano-immuno therapeutics
(Drug Delivery and Translational Research. 2024;14:3477–3493, 2024-05-03)Immunotherapy has emerged as a promising approach to cancer treatment, offering improved survival rates and enhanced patients’ quality of life. However, realizing the full potential of immunotherapy in ... -
Environmental performance and firm performance in Europe: The moderating role of board governance
(Corporate Social Responsibility and Environmental Management. 2024;31(6):5863–5880, 2024-07-01)This research presents novel insights into the relationship between environmental performance and firm performance, focusing on the moderating role of board governance. Unlike the single-dimensional ... -
Hybrid analytical surrogate-based process optimization via Bayesian symbolic regression
(Computers & Chemical Engineering. 2024;182:108563, 2024-01-09)Modular chemical process simulators are widespread in chemical industries to design and optimize production processes with sufficient accuracy. However, convergence issues and entrapment in local optima ... -
Algebraic surrogate-based flexibility analysis of process units with complicating process constraints
(Computers & Chemical Engineering. 2024;184:108630, 2024-03-11)Flexibility analyses are widespread in chemical engineering to quantify allowed deviations from nominal conditions. Standard approaches to perform flexibility analysis can be hard to apply if process ... -
Comparison of two peroxidases with high potential for biotechnology applications – HRP vs. APEX2
(Computational and structural biotechnology journal. 2024,23:742-751, 2024-01-12)Peroxidases are essential elements in many biotechnological applications. An especially interesting concept involves split enzymes, where the enzyme is separated into two smaller and inactive proteins ...