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High photostability in nonconventional coumarins with far-red/NIR emission through azetidinyl substitution
(American Chemical Society, 2018-08)
Replacement of electron-donating N,N-dialkyl groups with three- or four-membered cyclic amines (e.g., aziridine and azetidine, respectively) has been described as a promising approach to improve some ...
Combining biological processes with UV/H2O2 for metoprolol and metoprolol acid removal in hospital wastewater
(Elsevier, 2021-01-15)
The transformation products (TPs) of water contaminants generated during wastewater treatment can sometimes be equally or even more hazardous than the parent compounds. Therefore, for a comprehensive ...
Plasmodium falciparum apicomplexan-specific glucosamine-6-phosphate n-acetyltransferase is key for amino sugar metabolism and asexual blood stage development
(American Society for Microbiology, 2020-10)
ABSTRACT
UDP-N-acetylglucosamine (UDP-GlcNAc), the main product of the hexosamine biosynthetic pathway, is an important metabolite in protozoan parasites since its sugar moiety is incorporated into ...
Time-dependent mechanical properties in polyetherimide 3D-Printed parts are dictated by isotropic performance being accurately predicted by the generalized time hardening model
(MDPI, 2020-03)
The Fused-Deposition Modelling (FDM) technique has transformed the manufacturing discipline by simplifying operational processes and costs associated with conventional technologies, with polymeric ...
Empirical analysis of the incidence of accidents in the workplace on firms' financial performance
(Elsevier, 2014-12)
This paper performs an empirical analysis on the incidence of labor accidents on firm financial performance. With data on financial statements and labor accidents of 299 Spanish firms for 6 different ...
A Poset-Generalizability Method for Human Development Indicators
(Springer, 2021-06-17)
The paper introduces a poset-generalizability perspective for analysing human development indicators. It suggests a new method for identifying admissibility of diferent informational spaces and criteria ...
Two-component systems of mycobacterium tuberculosis as potential targets for drug development
(Asociación de Químicos e Ingenieros del Instituto Químico de Sarrià, 2014-07)
Tuberculosis, caused by Mycobacterium tuberculosis, is a global health problem with approximately two million deaths every year. Furthermore, up to one-third of the world population is infected with ...
An online course to teach ATD research praxeologies: The ICMI awardees multimedia online resources
(Pontifícia Universidade Católica de São Paulo, 2020)
We present some of the main elements of a project of Multimedia Online Resource addressed to international researchers willing to be initiated in the ATD. The project was launched by the executive ...
The Masking Game: Design of Activatable Antibodies and Mimetics for Selective Therapeutics and Cell Control
(American Chemical Society, 2021-04-26)
The high selectivity and affinity of antibody binding havemade antibodies all-pervasive tools in therapy, diagnosis, and basic science.A plethora of chemogenetic approaches has been devised to makeantibodies ...
Substrate distortion in the Michaelis complex of Bacillus 1,3–1,4-β-glucanase: insight from first principles molecular dynamics simulations
(The American Society for Biochemistry and Molecular Biology, 2006-01)
The structure and dynamics of the enzyme-substrate complex of Bacillus 1,3–1,4-β-glucanase, one of the most active glycoside hydrolases, is investigated by means of Car-Parrinello molecular dynamics ...