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Ara mostrant els elements 196-215 de 317
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Multiscale modeling for complex chemical systems: highlights about the Nobel Prize in Chemistry 2013
(Afinidad. Vol.71, n.566 (2014), p.89-94, 2014-04)The Nobel Prize in Chemistry 2013 was awarded jointly to Martin Karplus, Michael Levitt and Arieh Warshel for the development of multiscale models for complex chemical systems. From the simplest ... -
Nanomedicine in non-small cell lung cancer: from conventional treatments to immunotherapy
(Cancers. Vol.12, n.6 (2020), 1609, 2020-06)Non-small cell lung cancer (NSCLC) remains the most common cause of cancer-related mortality. The heterogeneous nature of this disease hinders its diagnosis and treatment, requiring continuous advances ... -
Nanopartículas de sílice: preparación y aplicaciones en biomedicina
(Afinidad. Vol.71, n.565 (2014), p.20-31, 2014-01)Actualmente, un importante número de avances científicos se fundamentan en la utilización de nanopartículas cómo superficies de actuación, vehículos de transporte, en procesos relacionados con aplicaciones ... -
Nanoscale characterization coupled to multi-parametric optimization of Hi5 cell transient gene expression
(Applied Microbiology and Biotechnology, 2018-10-13)Polyethylenimine (PEI)-based transient gene expression (TGE) is nowadays a well-established methodology for rapid protein production in mammalian cells, but it has been used to a much lower extent in ... -
Nb–C thin films prepared by DC-MS and HiPIMS: Synthesis, structure, and tribomechanical properties
(Surface and Coatings Technology. Vol.422 (2021), 127569, 2021-09-25)Nanostructured Nb-C thin films were prepared by direct current magnetron sputtering (DC-MS) and high-power impulse magnetron sputtering (HiPIMS). The films were characterized in depth by X-ray diffraction ... -
New developments in vertebroplasty materials
(Afinidad. Vol.75, n.583 (2018), p.165-174, 2018-07)Increasing life expectancy is leading to an increase in age-related diseases, like osteoporosis, which often involve the breakdown of bone. One of the main problems related with such disease is the ... -
Nitrogen positional scanning in tetramines active against HIV-1 as potential CXCR4 inhibitors
(Organic & Biomolecular Chemistry. Vol.14, n.4 (2016), p.1455-1472, 2015-12)The paradigm, derived from bicyclams and other cyclams, by which it is necessary to use the p-phenylene moiety as the central core in order to achieve high HIV-1 antiviral activities has been reexamined ... -
Una nova taula periòdica per a l'ensenyament secundari
(Educació Química. N.15 (2013), p.62, 2015) -
Novel grafted electrochemical interface for covalent glucose oxidase immobilization using reactive pentafluorophenyl methacrylate
(Colloids and Surfaces B: Biointerfaces, 2018-12-01)One of the most important factors for the proper functioning of enzymatic electrochemical biosensors is the enzyme immobilization strategy. In this work, glucose oxidase was covalently immobilized using ... -
Novel α-mannose-functionalized poly(β-amino ester) nanoparticles as mRNA vaccines with increased antigen presenting cell selectivity in the spleen
(Journal of Materials Chemistry B, 2023-06-14)mRNA vaccination has emerged as a prominent therapy for the future of medicine. Despite the colossal advance in this technology and worldwide efficacy proof (ca. COVID vaccines), mRNA carriers still ... -
Octanol-water partition coefficients of highly hydrophobic photodynamic therapy drugs: a computational study
(Afinidad. Vol.70, n.564 (2013), p.250-256, 2013-10)Photodynamic therapy is a novel treatment for solid tumors based on the selective induction of cell death by the generation of cytotoxic reactive oxygen species within neoplastic tissues. Oxygen ... -
Oligopeptide-modified poly(beta-amino ester)s-coated AdNuPARmE1A: boosting the efficacy of intravenously administered therapeutic adenoviruses
(Theranostics. Vol.10, n.6 (2020), p. 2744-2758, 2020-02)Oncolytic adenoviruses are used as agents for the treatment of cancer. However, their potential is limited due to the high seroprevalence of anti-adenovirus neutralizing antibodies (nAbs) within the ... -
Omplim de simulacions la classe de química!
(Educació Química. N.22 (2016), p.4-12, 2016)Les simulacions són una eina útil per a l'ensenyament de la ciència. L'ús de simulacions facilita la il·lustració dels conceptes científics i el desenvolupament d'activitats d'indagació en què l'alumne ... -
On the mechanism of Candida tropicalis biofilm reduction by the combined action of naturally-occurring anthraquinones and blue light
(PLoS ONE. Vol.12, n.7 (2017), e0181517, 2017-07)The photoprocesses involved in the photo-induced Candida tropicalis biofilm reduction by two natural anthraquinones (AQs), rubiadin (1) and rubiadin-1-methyl ether (2), were examined. Production of ... -
On the relationship between compliance with recommendations on the audit committee of codes of good practices and financial reporting quality
(Journal of Management and Governance. Vol.22, n.4 (2018), p.921-946, 2018-03)Codes of good practices provide a soft alternative to the hard legislation approach to corporate governance. These codes include a set of recommendations that companies are expected to follow in order ... -
Online discussion forums with embedded streamed videos on distance courses
(Journal of Technology and Science Education. Vol 4, n.1 (2014), p.25-38, 2014)Existing literature on education and technology has frequently highlighted the usefulness of online discussion forums for distance courses; however, the majority of such investigations have focused their ... -
Operations Management en las empresas del siglo XXI
(Estudios Empresariales. Número 148(2015), p.67-71, 2015) -
Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator
(eLIFE. Vol.6 (2017), e23545, 2017-04)Light-operated drugs constitute a major target in drug discovery, since they may provide spatiotemporal resolution for the treatment of complex diseases (i.e. chronic pain). JF-NP-26 is an inactive ... -
Optical writing and reading with a photoactivatable carbazole
(Physical Chemistry Chemical Physics. Vol.17, n.17 (2015), p.11140-11143, 2015-03)The fluorescence of a carbazole chromophore can be activated irreversibly under optical control with the photoinduced opening of an oxazine ring. In proximity to silver nanoparticles, the quantum ... -
Optimización y revalidación del análisis de nitrógeno por el método Kjeldahl en muestras de taurina
(Afinidad. Vol.66, n.541 (2009), p.200-205, 2009-05)En el presente artículo, se ha optimizado y se ha revalidado el procedimiento de análisis de nitrógeno en muestras de taurina mediante el método Kjeldahl. La Asociación Española de Farmacéuticos de la ...