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An automated classification pipeline for tables in pharmacokinetic literature
(Scientific reports, 2025, 15: 10071, 2025-03)Pharmacokinetic (PK) models are essential for optimising drug candidate selection and dosing regimens in drug development. Preclinical and population PK models benefit from integrating prior knowledge ... -
Determinants and outcomes of physical activity in patients with COPD: a systematic review
(Thorax, 2014, 69: 731-739, 2014-02)Background The relationship between physical activity, disease severity, health status and prognosis in patients with COPD has not been systematically assessed. Our aim was to identify and summarise ... -
Characterisation and prognosis of undiagnosed chronic obstructive pulmonary disease patients at their first hospitalisation
(BMC Pulmonary Medicine, 2015, 15: 4, 2015-01)Background Under-diagnosis of COPD is an important unmet medical need. We investigated the characteristics and prognosis of hospitalised patients with undiagnosed COPD. Methods The PAC-COPD cohort ... -
Long-term efficacy and effectiveness of a behavioural and community-based exercise intervention (Urban Training) to increase physical activity in patients with COPD: a randomised controlled trial
(European respiratory journal, 2018, 52(4):1800063, 2018-12)There is a need to increase and maintain physical activity in patients with chronic obstructive pulmonary disease (COPD). We assessed 12-month efficacy and effectiveness of the Urban Training intervention ... -
Validation of walking trails for the urban training of chronic obstructive pulmonary disease patients
(PLoS One, 2016, 11(1): e0146705, 2016-01)Purpose Accessible interventions to train patients with chronic obstructive pulmonary disease (COPD) are needed. We designed urban trails of different intensities (low, moderate and high) in different ... -
The PROactive instruments to measure physical activity in patients with chronic obstructive pulmonary disease
(European respiratory journal, 2015, 46(4):988-1000, 2015-06)No current patient-centred instrument captures all dimensions of physical activity in chronic obstructive pulmonary disease (COPD). Our objective was item reduction and initial validation of two instruments ... -
Preference trials: An underexplored design in musculoskeletal research
(JOSPT Methods, 2025, 1(2): 1-12, 2025-03)BACKGROUND: Incorporating patients’ preferences into randomized controlled trials (RCTs) enhances the relevance and applicability of research findings to clinical practice. Person- and patient-centered ... -
Relation between length of exposure to epidural analgesia during labour and birth mode
(International Journal of Environmental Research and Public Health, 2019, 16(16): 2928, 2019-08)Objective: To appraise the relationship between the length of exposure to epidural analgesia and the risk of non-spontaneous birth, and to identify additional risk factors. This study is framed within ... -
The Chester step test is a reproducible tool to assess exercise capacity and exertional desaturation in post-COVID-19 patients
(Healthcare, 2023, 11(1), 51, 2022-12)Many people recovering from an acute episode of coronavirus disease (COVID-19) experience prolonged symptoms. Exercise testing is a feasible and cost-effective option for assessing exercise tolerance, ... -
Drug-drug interactions in metastatic hormone-sensitive prostate cancer (mHSPC): practical considerations for treating men with androgen receptor pathway inhibitors and common medications in this stage
(Expert Opinion on Drug Metabolism & Toxicology, 2025, 19 març, 2025-03)Introduction New androgen receptor pathway inhibitors (ARPIs) are an essential part of the treatment strategy for patients with metastatic hormone-sensitive prostate cancer (mHSPC). Despite the good ... -
Validity of prognostic models of critical COVID-19 is variable. A systematic review with external validation
(Journal of Clinical Epidemiology, 2023, 159: 274-288, 2023-07)Objectives To identify prognostic models which estimate the risk of critical COVID-19 in hospitalized patients and to assess their validation properties. Study Design and Setting We conducted a ... -
Physical performance testing in post-COVID-19 patients: protocol for a systematic review of psychometric measurement properties
(BMJ Open, 2022, 12: e063316, 2023-04)Introduction COVID-19 is an infectious disease that causes severe acute respiratory syndrome. A large variety of exercise capacity tests are used for the evaluation of post-COVID-19 patients, but the ... -
Effect of pulmonary hypertension on exercise tolerance in patients with COPD: a prognostic systematic review and meta-analysis
(European respiratory review, 2021, 30(160): 200321, 2021-04)Background Pulmonary hypertension (PH) is a frequent complication in patients with COPD. Objective To determine if, in patients with COPD, the presence of PH decreases exercise tolerance. Methods We ... -
Maximal respiratory pressure reference equations in healthy adults and cut-off points for defining respiratory muscle weakness
(Archivos de bronconeumología, 2023, 59(12): 813-820, 2023-12)Introduction Maximal inspiratory and expiratory pressures (PImax/PEmax) reference equations obtained in healthy people are needed to correctly interpret respiratory muscle strength. Currently, no clear ... -
Analysis of caesarean section rates using the Robson classification system at a university hospital in Spain
(International Journal of Environmental Research and Public Health, 2020, 17(5): 1575, 2020-02)Background: The WHO recommends the use of the Robson ten-group classification system (RTGCS) as an effective monitoring and analysis tool to assess the use of caesarean sections (CS). The present study ... -
Oxytocin administration in low-risk women, a retrospective analysis of birth and neonatal outcomes
(International Journal of Environmental Research and Public Health, 2021, 18(8): 4375, 2021-04)Background: In recent years, higher than the recommended rate of oxytocin use has been observed among low-risk women. This study examines the relationship between oxytocin administration and birth ... -
Obstetric–neonatal care during birth and postpartum in symptomatic and asymptomatic women infected with SARS-CoV-2: A retrospective multicenter study
(International Journal of Environmental Research and Public Health, 2022, 19(9): 5482, 2022-04)This study analyses the obstetric–neonatal outcomes of women in labour with symptomatic and asymptomatic COVID-19. A retrospective, multicenter, observational study was carried out between 1 March 2020 ... -
A comparison between midwifery and obstetric care at birth in Spain: Across-sectional study of perinatal outcomes
(International journal of nursing studies, 2022, 126: 104129, 2022-02)Background The organizational structure of maternity services determines the choice of which professionals provide care during pregnancy, birth, and the postnatal period, and it influences the kind of ... -
Systematic review of ethical issues in perinatal mental health research
(Nursing ethics, 2023, 30(4): 482–499, 2023-06)BackgroundMaternal mental health during the peripartum period is critically important to the wellbeing of mothers and their infants. Numerous studies and clinical trials have focused on various aspects ... -
Perinatal outcomes at birth in women infected and non-infected with SARS-CoV-2: A retrospective study
(Healthcare, 2023, 11(21): 2833, 2023-10)Background: Coronavirus disease 2019 (COVID-19) was declared as a pandemic and public health emergency on 11 March 2020 by the World Health Organization. Different clinical trials on the efficacy of ...