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dc.contributorUniversitat Ramon Llull. IQS
dc.contributor.authorArriagada, Francisco
dc.contributor.authorCorrea, Olosmira
dc.contributor.authorGünther, Germán
dc.contributor.authorNonell, Santi
dc.contributor.authorMura, Francisco
dc.contributor.authorOlea-Azar, Claudio
dc.contributor.authorMorales, Javier
dc.date.accessioned2019-05-06T14:19:21Z
dc.date.accessioned2023-07-13T05:44:45Z
dc.date.available2019-05-06T14:19:21Z
dc.date.available2023-07-13T05:44:45Z
dc.date.created2016
dc.date.issued2016-11-03
dc.identifier.urihttp://hdl.handle.net/20.500.14342/1055
dc.description.abstractMorin (2´,3, 4´,5,7-pentahydroxyflavone) is a flavonoid with several beneficial health effects. However, its poor water solubility and it sensitivity to several environmental factors avoid its use in applications like pharmaceutical and cosmetic. In this work, we synthetized morin-modified mesoporous silica nanoparticles (AMSNPs-MOR) as useful material to be used as potential nanoantioxidant. To achieve this, we characterized its adsorption kinetics, isotherm and the antioxidant capacity as hydroxyl radical (HO•) scavenger and singlet oxygen (¹O2) quencher. The experimental data could be well fitted with Langmuir, Freundlich and Temkin isotherm models, besides the pseudo-second order kinetics model. The total quenching rate constant obtained for singlet oxygen deactivation by AMSNPs-MOR was one order of magnitude lower than the morin rate constant reported previously in neat solvents and lipid membranes. The AMSNPs-MOR have good antioxidant properties by itself and exhibit a synergic effect with morin on the antioxidant property against hydroxyl radical. This effect, in the range of concentrations studied, was increased when the amount of morin adsorbed increased.eng
dc.format.extent22 p.
dc.language.isoeng
dc.publisherPLOS (Public Library of Science)
dc.relation.ispartofPlos One, 2016, vol.11
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International
dc.rights© L'autor/a
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.sourceRECERCAT (Dipòsit de la Recerca de Catalunya)
dc.subject.otherFlavonoides
dc.subject.otherCosmètica
dc.subject.otherCompostos químics
dc.titleMorin flavonoid adsorbed on mesoporous silica, a novel antioxidant nanomaterial
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.rights.accessLevelinfo:eu-repo/semantics/openAccess
dc.embargo.termscap
dc.subject.udc546
dc.identifier.doihttps://doi.org/10.1371/journal.pone.0164507


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Attribution-NonCommercial-NoDerivatives 4.0 International
Excepto si se señala otra cosa, la licencia del ítem se describe como http://creativecommons.org/licenses/by-nc-nd/4.0/
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