Listando Recerca por materia "616"

Mostrando ítems 1-20 de 33

    • Activity of the novel BCR kinase inhibitor IQS019 in preclinical models of B-cell non-Hodgkin lymphoma 

      Borrell Bilbao, José Ignacio; Teixidó i Closa, Jordi; Puig de la Bellacasa Cazorla, Raimon; Roué, Gaël; Balsas, P.; Esteve-Arenys, A.; Roldán, J.; Jiménez, L.; Rodríguez, V.; Valero, J. G.; Chamorro-Jorganes, A.; Matas-Céspedes, A.; Moros, A.; Martínez, A.; Campo, E.; Sáez-Borderías, A.; Pérez-Galán, P.; Colomer, D. (Journal of Hematology & Oncology. Vol.10, n.80 (2017), 2017-03)
      Background Pharmacological inhibition of B cell receptor (BCR) signaling has recently emerged as an effective approach in a wide range of B lymphoid neoplasms. However, despite promising clinical activity ...

    • Barriers and facilitators to research translation into health care decision making: a scoping review 

      Aymerich, Marta, 1968-; Carrión Ribas, Carme; Sànchez i Ruiz, Emília; Gallo de Puelles, Pedro; Caïs, Jordi; Arroyo Moliner, Liliana; Gené Badia, Joan (Annals of translational medicine and epidemiology, 2017, vol. 4, núm. 1, 2017-05)
      Background: To provide useful insights into the design of strategies to better put into practice health research outcomes in the case of cancer, heart disease and sexuallty transmitted infections, we ...

    • Cancer signaling transcriptome is upregulated in type 2 diabetes mellitus 

      Almanza Aguilera, Enrique; Hernáez, Álvaro; Corella Piquer, Dolores; Sanllorente Melenchon, Albert, 1990-; Ros Rahola, Emilio; Portolés, Olga; Valussi, Julieta; Estruch Riba, Ramon; Coltell, Oscar; Subirana Cachinero, Isaac; Canudas i Puig, Sílvia; Razquin, Cristina; Blanchart, Gemma; Nonell, Lara; Fitó Colomer, Montserrat; Castañer, Olga (Journal of clinical medicine, 2020, vol. 10, núm. 1, 85, 2020-12-29)
      We aimed to explore the differences in the whole transcriptome of peripheral blood mononuclear cells between elderly individuals with and without type 2 diabetes (T2D). We conducted a microarray-based ...

    • Efficacy of CT-P6 (trastuzumab biosimilar) versus reference trastuzumab in combination with pertuzumab in HER2-positive early-stage breast cancer: preclinical and real-life clinical data 

      Bernat Peguera, Adrià; Trigueros Peña, Macedonia; Ferrando Díez, Angelica; Ibáñez, Cristina; Bystrup, Sara; Martínez-Cardús, Anna; Margelí, Mireia; Martínez-Balibrea, Eva (The Breast, 2022, 62: 1-9, 2022-01)
      After the expiration of trastuzumab data exclusivity, biosimilar drugs were approved by regulatory agencies; among them, CT-P6 which was approved for the treatment of HER2-positive early- and advanced-breast ...

    • Epidemiological study of injuries arising from karting competition in children 

      Delmuns, Salvi; Roig, Marc; Javierre Garcés, Casimiro F.; Mans, Cristina; Giné-Garriga, Maria (Journal of Community Medicine and Health Education, 2014, vol. 4, núm. 4, 2014-07)
      Objective: The main aim was to define the impact and type of injuries in children aged from 7 to 15 years old competing in karting competition in Catalonia during the 2005-2009 periods. Secondary aims ...

    • Epidemiological study of injuries arising from karting competition in children 

      Delmuns, Salvi; Roig, Marc; Javierre Garcés, Casimiro F.; Mans, Cristina; Giné-Garriga, Maria (Journal of Community Medicine and Health Education, 2014, vol. 4, núm. 4, 2014-07)
      Objective: The main aim was to define the impact and type of injuries in children aged from 7 to 15 years old competing in karting competition in Catalonia during the 2005-2009 periods. Secondary aims ...

    • Erlotinib Promotes Ligand-Induced EGFR Degradation in 3D but Not 2D Cultures of Pancreatic Ductal Adenocarcinoma Cells 

      Betriu, Nausika; Semino, Carlos; Andreeva, Anna (Cancers, 2021-09-07)
      The epithelial growth factor receptor (EGFR) is a tyrosine kinase receptor that participates in many biological processes such as cell proliferation. In addition, EGFR is overexpressed in many epithelial ...

    • Extracellular vesicles and their current role in cancer immunotherapy 

      Giacobino, Carla; Canta, Marta; Fornaguera Puigvert, Cristina; Borrós i Gómez, Salvador; Cauda, Valentina (Cancers, 2021-05-10)
      Extracellular vesicles (EVs) are natural particles formed by the lipid bilayer and released from almost all cell types to the extracellular environment both under physiological conditions and in presence ...

    • Fine-tuning formulation and biological interaction of doxorubicin-loaded polymeric nanoparticles via electrolyte concentration modulation 

      Bofill Bonet, Carles; Gil Vives, Maria; Artigues Cladera, Margalida; Hernández Hernández, Marta; Borrós i Gómez, Salvador; Fornaguera Puigvert, Cristina (Journal of Molecular Liquids, 2023, vol. 390, part A, 122986, 2023-09)
      Doxorubicin (DOX) is amongst the most widely used chemotherapeutic drugs against various cancers. However, its controlled biodistribution to the tumor site at the required pharmacokinetics profile ...

    • Función física entre subgrupos de mayores de 55 años físicamente activos 

      Cuesta Vargas, Antonio I.; Giné-Garriga, Maria; González Sánchez, M. (Revista Internacional de Medicina y Ciencias de la Actividad Física y el Deporte, 2015, vol. 15, núm. 59, 2015-09)
      Objetivo: analizar de qué manera la capacidad neuromuscular de producir fuerza explosiva e isotónica máxima, en los miembros inferiores y en la espalda, contribuyen al equilibrio en mayores diferenciando ...

    • Función física entre subgrupos de mayores de 55 años físicamente activos 

      Cuesta Vargas, Antonio I.; Giné-Garriga, Maria; González Sánchez, M. (Revista Internacional de Medicina y Ciencias de la Actividad Física y el Deporte, 2015, vol. 15, núm. 59, 2015-09)
      Objetivo: analizar de qué manera la capacidad neuromuscular de producir fuerza explosiva e isotónica máxima, en los miembros inferiores y en la espalda, contribuyen al equilibrio en mayores diferenciando ...

    • Glycyrrhetinic acid-functionalized mesoporous silica nanoparticles for the co-delivery of DOX/CPT-PEG for targeting HepG2 cells 

      Sánchez García, David; Borrós i Gómez, Salvador; Fornaguera Puigvert, Cristina; Martínez Edo, Gabriel (Pharmaceutics. Vol.12, n.11 (2020), 1048, 2020-11)
      A pH-triggered mesoporous silica nanoparticle (MSN)-based nano-vehicle for the dual delivery of doxorubicin (DOX)/camptothecin-PEG (CPT-PEG) has been prepared. To enhance its selectivity, the nanoparticles ...

    • Inflammatory potential of diet and pancreatic cancer risk in the EPIC study 

      Cayssials, Valerie; Buckland, Genevieve; Crous-Bou, Marta; Bonet, Catalina; Weiderpass, Elisabete; Skie, Guri; Aune, Dagfnn; Heath, Alicia K.; Nøst, Therese Haugdahl; Masala, Giovanna; Agnoli, Claudia; Santucci de Magistris, Maria; Bueno de Mesquita, H. Bas; Derksen, Jeroen; Huybrechts, Inge; Ferrari, Pietro; Franklin, Oscar; Bodén, Stina; Schulze, Matthias B.; Huerta, José María; Barricarte, Aurelio; Sacerdote, Carlotta; Amiano, Pilar; Tumino, Rosario; Molina-Montes, Esther; Tjønneland, Anne; Kyrø, Cecilie; Severi, Gianluca; Boutron-Ruault, Marie-Christine; Rebours, Vinciane; Katzke, Verena Andrea; Agudo, Antonio; Jakszyn, Paula (European Journal of Nutrition, 2022, 61: 2313-2320, 2022-01)
      Purpose There is existing evidence on the potential role of chronic infammation in the pathogenesis of pancreatic cancer (PC) and on how risk may be modulated by dietary factors. Pro-infammatory diets ...

    • Inflammatory potential of the diet and risk of breast cancer in the European Investigation into Cancer and Nutrition (EPIC) study 

      Castro Espin, Carlota; Agudo, Antonio; Bonet, Catalina; Katzke, Verena Andrea; Turzanski‑Fortner, Renée; Aleksandrova, Krasimira; Schulze, Matthias B.; Tjønneland, Anne; Dahm, Christina C.; Quirós, José Ramón; Sánchez, María-José; Amiano, Pilar; Chirlaque, Maria-Dolores; Ardanaz, Eva; Masala, Giovanna; Sieri, Sabina; Tumino, Rosario; Sacerdote, Carlotta; Panico, Salvatore; May, Anne-Marie; Bodén, Stina; Gram, Inger Torhild; Skeie, Guri; Laouali, Nasser; Shah, Sanam; Severi, Gianluca; Aune, Dagfnn; Merritt, Melissa; Cairat, Manon; Weiderpass, Elisabete; Riboli, Elio; Dossus, Laure; Jakszyn, Paula (European Journal of Epidemiology, 2021, 36: 953-964, 2021-06)
      The role of chronic infammation on breast cancer (BC) risk remains unclear beyond as an underlying mechanism of obesity and physical activity. We aimed to evaluate the association between the infammatory ...

    • Inflammatory potential of the diet and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition study 

      Jakszyn, Paula; Cayssials, Valerie; Buckland, Genevieve; Perez-Cornago, Aurora; Weiderpass, Elisabete; Boeing, Heiner; Bergmann, Manuela M.; Vulcan, Alexandra; Ohlsson, Bodil; Masala, Giovanna; Cross, Amanda J.; Riboli, Elio; Ricceri, Fulvio; Dahm, Christina C.; Nyvang, Dorthe; Katzke, Verena Andrea; Kühn, Tilman; Kyrø, Cecilie; Tjønneland, Anne; Ward, Heather A.; Tsilidis, Konstantinos K.; Skeie, Guri; Sieri, Sabina; Sánchez, María-José; Huerta, José María; Amiano, Pilar; Lasheras-Mayo, Maria Cristina; Ardanaz, Eva; Mahamat-Saleh, Yahya; Boutron-Ruault, Marie-Christine; Carbonnel, Franck; Panico, Salvatore; Peppa, Eleni; Trichopoulou, Antonia; Karakatsani, Anna; Tumino, Rosario; Vermeulen, Roel; Jenab, Mazda; Gunter, Marc J.; Agudo, Antonio (International Journal of Cancer, 2020, 147(4): 1027-1039, 2020-08)
      Proinflammatory diets are associated with risk of developing colorectal cancer (CRC), however, inconsistencies exist in subsite- and sex-specific associations. The relationship between CRC and combined ...

    • Inflammatory potential of the diet and risk of gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) study 

      Agudo, Antonio; Cayssials, Valerie; Bonet, Catalina; Tjønneland, Anne; Overvad, Kim; Boutron-Ruault, Marie-Christine; Affret, Aurélie; Fagherazzi, Guy; Katzke, Verena Andrea; Schübel, Ruth; Trichopoulou, Antonia; Karakatsani, Anna; La Vecchia, Carlo; Palli, Domenico; Grioni, Sara; Tumino, Rosario; Ricceri, Fulvio; Panico, Salvatore; Bueno de Mesquita, H. Bas; Peeters, Petra H.; Weiderpass, Elisabete; Skeie, Guri; Nøst, Therese Haugdahl; Lasheras-Mayo, Maria Cristina; Rodríguez-Barranco, Miguel; Amiano, Pilar; Chirlaque, Maria-Dolores; Ardanaz, Eva; Ohlsson, Bodil; Dias, Joana A.; Nilsson, Lena M.; Myte, Robin; Khaw, Kay-Tee; Perez-Cornago, Aurora; Gunter, Marc; Huybrechts, Inge; Cross, Amanda J.; Tsilidis, Kostas; Riboli, Elio; Jakszyn, Paula (American Journal of Clinical Nutrition, 2018, 107(4):607-616, 2018-04)
      Background Chronic inflammation plays a critical role in the pathogenesis of the 2 major types of gastric cancer. Several foods, nutrients, and nonnutrient food components seem to be involved in the ...

    • Influence of social determinants, lifestyle, emotional well-being and the use of unconventional therapies in breast cancer progression in a cohort of women in Barcelona: protocol for the DAMA cohort 

      Puigpinós i Riera, Rosa; Continente Garcia, Xavier, 1980-; Serral Cano, Gemma, 1973-; Bargalló Castelló, Xavier; Doménech, Montserrat; Espinosa-Bravo, Martín; Grau, Jaume; Macià, Francesc; Manzanera i López, Rafael; Pla i Consuegra, Margarida; Quintana Ruiz, M. Jesús; Sala i Serra, Maria; Vidal García, Eulàlia (JMIR Research Protocols, 2017, vol. 6, núm. 12, 2017-12)
      Background: Breast cancer continues to be the most commonly diagnosed cancer in women. Breast cancer survivors face numerous problems, especially after completing the first year of intense treatment. ...

    • Nanomedicine in non-small cell lung cancer: from conventional treatments to immunotherapy 

      Fornaguera Puigvert, Cristina; Borrós i Gómez, Salvador; García-Fernández, Coral (Cancers. Vol.12, n.6 (2020), 1609, 2020-06)
      Non-small cell lung cancer (NSCLC) remains the most common cause of cancer-related mortality. The heterogeneous nature of this disease hinders its diagnosis and treatment, requiring continuous advances ...

    • Oligopeptide-modified poly(beta-amino ester)s-coated AdNuPARmE1A: boosting the efficacy of intravenously administered therapeutic adenoviruses 

      Borrós i Gómez, Salvador; Fornaguera Puigvert, Cristina; Brugada Vilà, Pau; Fillat i Fonts, Cristina; Cascante, Anna; Lázaro, Miguel Ángel; Castells-Sala, Cristina; Rovira-Rigau, Maria; Albertazzi, Lorenzo (Theranostics. Vol.10, n.6 (2020), p. 2744-2758, 2020-02)
      Oncolytic adenoviruses are used as agents for the treatment of cancer. However, their potential is limited due to the high seroprevalence of anti-adenovirus neutralizing antibodies (nAbs) within the ...

    • Photodynamic synergistic effect of pheophorbide a and doxorubicin in combined treatment against tumoral cells 

      Nonell, Santi; Bresolí Obach, Roger; Ruiz González, Rubén; Milán, Paula; Stockert, Juan Carlos; Villanueva, Angeles; Cañete, Magdalena (Cancers. Vol.9, n.2 (2017), 18, 2017-02)
      A combination of therapies to treat cancer malignancies is at the forefront of research with the aim to reduce drug doses (ultimately side effects) and diminish the possibility of resistance emergence ...