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A novel fluoro-chromogenic click reaction for the labelling of proteins and nanoparticles with near-IR theranostic agents
Nonell, S. (Santi); Planas, Oriol; Gallavardin, Thibault (Chemical Communications. Vol.51, n.26 (2015), p.5586-5589, 2014-12)Reaction of porphycene isothiocyanates with primary and secondary amines leads to the formation of thiazolo[4,5-c]porphycenes, with a substantial shift in the absorption and fluorescence spectra. The ... -
Smart dual-functionalized gold nanoclusters for spatio-temporally controlled delivery of combined chemo- and photodynamic therapy
Nonell, Santi; Planas, Oriol; Gallavardin, Thibault; Nieves, Ingrid; Tabero, Andrea; Villanueva, Ángeles (Nanomaterials. Vol.10, n.12 (2020), 2474, 2020-12)We report the preparation of gold nanoclusters (AuNCs) as a delivery vehicle for the clinically approved photodynamic and chemotherapeutic agents Protoporphyrin IX (PpIX) and doxorubicin (DOX), respectively, ... -
Synthesis, photophysical characterization and photoinduced antibacterial activity of methylene blue-loaded amino- and mannose-targeted mesoporous silica nanoparticles
Planas Marquès, Oriol; Bresolí Obach, Roger; Nos, Jaume; Gallavardin, Thibault; Ruiz González, Rubén; Agut Bonsfills, Montserrat; Nonell, Santi (Molecules. Vol.20, n.4 (2015), p.6284-6298, 2015-04)Over the last 20 years, the number of pathogenic multi-resistant microorganisms has grown steadily, which has stimulated the search for new strategies to combat antimicrobial resistance. Antimicrobial ...