Mostra el registre parcial de l'element

dc.contributorUniversitat Ramon Llull. IQS
dc.contributor.authorDugan, James Michael
dc.contributor.authorColominas, Carles
dc.contributor.authorGarcía Granada, Andrés-Amador
dc.contributor.authorClaeyssens, Frederik
dc.date.accessioned2024-10-25T09:55:40Z
dc.date.available2024-10-25T09:55:40Z
dc.date.issued2021-11-22
dc.identifier.issn2296-8016ca
dc.identifier.urihttp://hdl.handle.net/20.500.14342/4476
dc.description.abstractThis study reports a route to spatial control of neuronal adhesion onto Diamond-Like Carbon (DLC) by surface functionalisation by poly (oligo-ethyleneglycol methacrylate) (pOEGMA) and consequent laser ablation to produce cell adhesive tracks. DLC can be deposited as a tough and low friction coating on implantable devices and surgical instruments and has favourable properties for use as a biomaterial. The pOEGMA surface coating renders the DLC surface antifouling and the laser ablation creates graphitised tracks on the surface. The surfaces were coated with laminin, which adhered preferentially to the ablation tracks. The patterned surfaces were investigated for neuronal cell growth with NG108-15 cells for short term culture and rat neural stem cells for longer term culture. The cells initially adhered highly selectively to the ablation tracks while longer term cell culture revealed a more uniform cell coverage of the surface.ca
dc.format.extent13 p.ca
dc.language.isoengca
dc.publisherFrontiers Mediaca
dc.relation.ispartofFrontiers in Bioengineering and Biotechnologyca
dc.rights© L'autor/aca
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subject.otherLaser ablationca
dc.subject.otherDiamond-like carbonca
dc.subject.otherPoly(oligo (ethylene glycol) methacrylate)ca
dc.subject.otherAtom transfer radical polymerizationca
dc.subject.otherNeuronal cell cultureca
dc.titleSpatial Control of Neuronal Adhesion on Diamond-Like Carbonca
dc.typeinfo:eu-repo/semantics/articleca
dc.rights.accessLevelinfo:eu-repo/semantics/openAccess
dc.embargo.termscapca
dc.subject.udc576ca
dc.identifier.doihttps://doi.org/10.3389/fmats.2021.756055ca
dc.relation.projectIDinfo:eu-repo/grantAgreement/EPSRC/EP/K002503/1ca
dc.relation.projectIDinfo:eu-repo/grantAgreement/EPSRC/EP/I007695/1ca
dc.relation.projectIDinfo:eu-repo/grantAgreement/Medical Research Council/MR/L012669/1ca
dc.description.versioninfo:eu-repo/semantics/publishedVersionca


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Mostra el registre parcial de l'element

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