Articles publicats en revistes: Recent submissions
Now showing items 221-240 of 679
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NanoFN10: A High-Contrast Turn-On Fluorescence Nanoprobe for Multiphoton Singlet Oxygen Imaging
(Sensors 2023, 23(10), 4603, 2023-05)An “off-on” fluorescent nanoprobe for near-infrared multiphoton imaging of singlet oxygen has been developed. The nanoprobe comprises a naphthoxazole fluorescent unit and a singlet-oxygen-sensitive furan ... -
De-Novo Design of pre-miR-21 Maturation Inhibitors: Synthesis and Activity Assessment
(Chemistry - A European Journal 2023, 29(40),e202300825, 2023-07-14)Targeting RNA with small molecules is a major challenge of current medicinal chemistry, and the identification and design of original scaffolds able to selectively interact with an RNA target remains ... -
Biomineralization in Three-Dimensional Scaffolds Based on Bacterial Nanocellulose for Bone Tissue Engineering: Feature Characterization and Stem Cell Differentiation
(Polymers 2023, 15(9), 2012, 2023-05)Bacterial nanocellulose (BNC) has a negative surface charge in physiological environments, which allows the adsorption of calcium ions to initiate the nucleation of different calcium phosphate phases. ... -
Poly(β-amino ester)s-Based Delivery Systems for Targeted Transdermal Vaccination
(Pharmaceutics 2023, 15(4), 1262, 2023-04)Nucleic acid vaccines have become a transformative technology to fight emerging infectious diseases and cancer. Delivery of such via the transdermal route could boost their efficacy given the complex ... -
Cognitive decline in diabetic mice predisposed to Alzheimer’s disease is greater than in wild type
(Life Science Alliance 2023, 6 (6), e202201789, 2023-06)In this work, we tested the hypothesis that the development of dementia in individuals with type 2 diabetes (T2DM) requires a genetic background of predisposition to neurodegenerative disease. As a proof ... -
Optimization of 3D autologous chondrocyte-seeded polyglycolic acid scaffolds to mimic human ear cartilage
(Biomaterials Science 2023, 13 (10), 2023-05)Auricular reconstruction in children with microtia is one of the more complex procedures in plastic surgery. Obtaining sufficient native material to build an ear requires harvesting large fragments of ... -
Overview of the current situation relating to chemical engineering degree courses
(Education for Chemical Engineers 2023, 43, 2023-04)In 2020, the Conference of Chemical Engineering Directors and Deans (CODDIQ) proposed the creation of an observatory to monitor chemical engineering degrees in Spain. This representative radiography of ... -
Nucleic acid-loaded poly(beta-aminoester) nanoparticles for cancer nano-immuno therapeutics
(Drug Delivery and Translational Research. 2024;14:3477–3493, 2024-05-03)Immunotherapy has emerged as a promising approach to cancer treatment, offering improved survival rates and enhanced patients’ quality of life. However, realizing the full potential of immunotherapy in ... -
Environmental performance and firm performance in Europe: The moderating role of board governance
(Corporate Social Responsibility and Environmental Management. 2024;31(6):5863–5880, 2024-07-01)This research presents novel insights into the relationship between environmental performance and firm performance, focusing on the moderating role of board governance. Unlike the single-dimensional ... -
Hybrid analytical surrogate-based process optimization via Bayesian symbolic regression
(Computers & Chemical Engineering. 2024;182:108563, 2024-01-09)Modular chemical process simulators are widespread in chemical industries to design and optimize production processes with sufficient accuracy. However, convergence issues and entrapment in local optima ... -
Algebraic surrogate-based flexibility analysis of process units with complicating process constraints
(Computers & Chemical Engineering. 2024;184:108630, 2024-03-11)Flexibility analyses are widespread in chemical engineering to quantify allowed deviations from nominal conditions. Standard approaches to perform flexibility analysis can be hard to apply if process ... -
Comparison of two peroxidases with high potential for biotechnology applications – HRP vs. APEX2
(Computational and structural biotechnology journal. 2024,23:742-751, 2024-01-12)Peroxidases are essential elements in many biotechnological applications. An especially interesting concept involves split enzymes, where the enzyme is separated into two smaller and inactive proteins ... -
High-Compression Crash Simulations and Tests of PLA Cubes Fabricated Using Additive Manufacturing FDM with a Scaling Strategy
(Computation. 2024;12(3):40, 2024-02-23)Impacts due to drops or crashes between moving vehicles necessitate the search for energy absorption elements to prevent damage to the transported goods or individuals. To ensure safety, a given level ... -
A near-infrared light-activatable Ru(ii)-coumarin photosensitizer active under hypoxic conditions
(Chemical Space 2023, 15(26), 2023-07-14)Photodynamic therapy (PDT) represents a promising approach for cancer treatment. However, the oxygen dependency of PDT to generate reactive oxygen species (ROS) hampers its therapeutic efficacy, especially ... -
Exploring Structure–Activity Relationships in Photodynamic Therapy Anticancer Agents Based on Ir(III)-COUPY Conjugates
(Journal of Medicinal Chemistry 2023, 66 (12), 2023-06-22)Photodynamic therapy holds great promise as a non-invasive anticancer tool against drug-resistant cancers. However, highly effective, non-toxic, and reliable photosensitizers with operability under ... -
Cyclic Homo- and Heterohalogen Di-λ3-diarylhalonium Structures
(Journal of the American Chemical Society 2023, 145 (25), 13796–13804, 2023-06-28)In the context of the ever-growing interest in the cyclic diaryliodonium salts, this work presents synthetic design principles for a new family of structures with two hypervalent halogens in the ring. ... -
Environmental concentrations of tire rubber-derived 6PPD-quinone alter CNS function in zebrafish larvae
(Science of The Total Environment 2023, 896, 165240, 2023-10-20)N-(1,3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine quinone (6PPD-quinone) is a degradation product of 6PPD, an antioxidant widely used in rubber tires. 6PPD-quinone enters aquatic ecosystems through ... -
Study of Elastin, Hydrolyzed Collagen and Collagen-like Products in a Tri-Layered Chitosan Membrane to Test Anti-Aging Skin Properties
(International Journal of Molecular Sciences 2023, 24(13), 11016, 2023-07-01)The use of animal testing in the cosmetic industry is already prohibited in more than 40 countries, including those of the EU. The pressure for it to be banned worldwide in the future is increasing, so ... -
A machine learning approach to predict cellular uptake of pBAE polyplexes
(Biomaterials Science 2023, 12(17), 5697-6002, 2023-09)The delivery of genetic material (DNA and RNA) to cells can cure a wide range of diseases but is limited by the delivery efficiency of the carrier system. Poly β-amino esters (pBAEs) are promising ... -
High-consistency silicone rubber with reduced Young's modulus. An industrial option to dielectric silicone rubber
(Journal of Applied Polymer Science, 140(37), e54405, 2023-10-05)Flexible capacitive sensors based on silicone rubber have gained importance inboth academic and industrial fields due to their advantages, including lowpower consumption and high stability to temperature, ...