Now showing items 101-120 of 679

    • An antibody-photosensitiser bioconjugate overcomes trastuzumab resistance in HER2-positive breast cancer 

      Jordà Redondo, Mireia; Piqueras, Ana; Castillo, Ana; Fernandez, Pedro Luis; Bresolí Obach, Roger; Blay, Lidia; Julian Ibañez, Joan Francesc; Nonell, Santi (European Journal of Medicinal Chemistry 2025, 290, 2025-06-05)
      HER2-positive breast cancer, characterized by the overexpression of HER2 receptors, often develops resistance to trastuzumab, limiting its therapeutic efficacy. In this study, we explore the use of ...
    • The interplay of author and editor gender in acceptance delays: evidence from accounting journals 

      Argilés-Bosch, J.M.; Kasperskaya, Yuliya; Garcia-Blandon, Josep; Ravenda, Diego (Scientometrics 2025, 130, 2025-03)
      The objective of this study is to examine the impact of the gender of editors and authors, as well as their interaction, on acceptance delays (ACCDEL) of articles. We focus on genders of the corresponding ...
    • Thermophysical Characterization of Sustainable Pathways for Hydrofluorocarbons Separation Utilizing Deep Eutectic Solvents 

      Alencar, L.V.T.D.; González Barramuño, Bastián; Rodriguez Reartes, S.B.; Quinteros-Lama, Héctor; Garrido, J.M.; Codera, Victoria; Pou, Josep Oriol; Tavares, Frederico; González Olmos, Rafael; Llovell Ferret, Félix Lluís (Journal of Industrial and Engineering Chemistry 2025, 146, 2025-06-25)
      The widespread use of hydrofluorocarbons (HFCs) in refrigeration ushered in a significant environmental challenge due to their high global warming potential. Effective recovery and separation techniques ...
    • A POCIS-based approach for the monitoring of pharmaceuticals in wastewater treatment plants: Calibration and deployment challenges 

      Domínguez García, Pol; Ortiz Almirall, Xavier; Gómez-Canela, Cristian (Environmental Pollution 2025, 367, 2025-02-15)
      The impact of pharmaceuticals in aquatic environments requires complementary monitoring techniques to the more conventional grab sampling approach for an improved sample representativity. This study ...
    • CEO demographics and gender diversity in senior management in large Scandinavian firms 

      Garcia-Blandon, Josep; Argilés-Bosch, J.M.; Ravenda, Diego (Gender in Management. 2024;39(1):1-17, 2024-01-23)
      Purpose This study aims to investigate whether chief executive officer (CEO) demographics are associated with gender diversity in senior management in the Scandinavia region. Design/methodology/ap ...
    • Development of Electrochemical and Colorimetric Biosensors for Detection of Dopamine 

      Khan, Rimsha; Anjum, Saima; Fatima, Nishat; Farooq, Nosheen; Shaheen, Aqeela; Fernandez Garcia, Javier; Khan, Muhammad Imran; Shanableh, Abdallah (Chemosensors. 2024;12(7):126, 2024-07-03)
      Neurotransmitters are essential chemical messengers required for proper brain function, and any changes in their concentrations can lead to neuronal diseases. Therefore, sensitive and selective detection ...
    • Synergistic Effect of NiAl-Layered Double Hydroxide and Cu-MOF for the Enhanced Photocatalytic Degradation of Methyl Orange and Antibacterial Properties 

      Batool, Iqra; Aroob, Sadia; Anwar, Farheen; Taj, Muhammad Babar; Baamer, Doaa F.; Almasoudi, Afaf; Ali, Omar Makram; Aldahiri, Reema H.; Alsulami, Fatimah Mohammad H.; Khan, Muhammad Imran; Fernandez Garcia, Javier (Catalysts. 2024;14(10):719, 2024-10-15)
      This study synthesized NiAl-layered double hydroxide (LDH)/Cu-MOF photocatalyst using a simple impregnation method involving NiAl-LDH and Cu-MOF. The successful synthesis was confirmed through Fourier ...
    • Synthesis, Magnetic, and Photocatalytic Activity of Polypyrrole-Based TiO2–Fe Catalyst for Wastewater Treatment 

      Nazir, Muhammad; Javaid, Sana; Afzal, Hina; TAJ, Dr. Muhammad Babar; Baamer, Doaa F.; Almasoudi, Afaf; Aldahiri, Reema H.; Ali, Omar Makram; Khan, Muhammad Imran; Ahmed, Muhammad Mahboob; Shanableh, Abdallah; Fernandez Garcia, Javier (Catalysts. 2024;14(10):692, 2024-10-05)
      The primary aim of this study is to investigate the degradation efficacy of the Ppy/TiO2-Fe photocatalyst for MB dye in an aqueous solution. Firstly, the direct addition of TiO2 and Fe was done to prepare ...
    • Efficient Hydroxyapatite Extraction from Salmon Bone Waste: An Improved Lab-Scaled Physico-Chemico-Biological 

      Muñoz, Francisco; Haidar, Ziyad S.; Puigdollers, Andreu; Guerra, Ignacio; Padilla, María Cristina; Ortega, Nicole; Balcells, Mercedes; García, María José (Molecules, 2024;29(17):4002, 2021-08-24)
      The demand for novel tissue grafting and regenerative wound care biomaterials is growing as traditional options often fall short in biocompatibility, functional integration with human tissue, associated ...
    • A Tunable Soft Silicone Bioadhesive for Secure Anchoring of Diverse Medical Devices to Wet Biological Tissue 

      Singh, Manisha; Teodorescu, Debbie; Rowlett, Meagan; Wang, Sophie X.; Balcells, Mercedes; Park, Clara; Bernardo, Bruno; McGarel, Sian; Reeves, Charlotte; Mehra, Mandeep R.; Zhao, Xuanhe; Yuk, Hyunwoo; Roche, Ellen (Advanced Materials. 2024;36(3):2307288, 2024-01-18)
      Silicone is utilized widely in medical devices for its compatibility with tissues and bodily fluids, making it a versatile material for implants and wearables. To effectively bond silicone devices to ...
    • La crisis del progreso como promesa secular. Una lectura teológico-política del giro reaccionario en la segunda década del siglo XXI 

      Casanovas Combalia, Xavier (Pensamiento. Revista de Investigación e Información Filosófica. 2024;80(309):617-635, 2024-12-19)
      A través del examen de fenómenos políticos recientes en Estados Unidos y Rusia, junto con los discursos ideológicos y filosóficos que los respaldan (QAnon, Dugin), el actual artículo analiza el resurgir ...
    • EEG hyperexcitability and hyperconnectivity linked to GABAergic inhibitory interneuron loss following traumatic brain injury 

      May, Hazel; Tsikonofilos, Konstantinos; Donat, Cornelius; Sastre, Magdalena; Kozlov, Andriy; Sharp, David; Bruyns-Haylett, Michael (Brain Communications, 2024;6(6):fcae385, 2024-11-27)
      Traumatic brain injury represents a significant global health burden and has the highest prevalence among neurological disorders. Even mild traumatic brain injury can induce subtle, long-lasting changes ...
    • Bistable boundary conditions implying codimension 2 bifurcations 

      Rand, David; Saez, Meritxell (Nonlinearity 2025, 38, 2025-03-14)
      We consider generic families Xθ of smooth dynamical systems depending on parameters θ ∈ P where P is a 2-dimensional simply connected domain and assume that each Xθ only has a finite number of restpoints ...
    • The Ignatian Way: Transforming people and communities 

      Peralta Ramos, Jorge; Hernandez-Maskivker, Gilda (Journal of Tourism and Heritage Research. 2024;7(3):89-103, 2024-07-05)
      The Ignatian Way (IW) is a pilgrimage route that Saint Ignatius of Loyola took in 1522, which goes through five different Autonomous Communities in the north of Spain, starting in the Basque Country ...
    • Motor and Non-Motor Effects of Acute MPTP in Adult Zebrafish: Insights into Parkinson’s Disease 

      Tagkalidou, Niki; Stevanović, Marija; Romero Alfano, Irene; Elizalde-Velazquez, Gustavo Axel; Selene Elizabeth, Herrera-Vázquez; Prats, Eva; Gómez-Canela, Cristian; Gómez-Oliván, Leobardo Manuel; Raldua, Demetrio (International Journal of Molecular Sciences 2025, 26(4), 2025-02-02)
      Parkinson’s disease (PD), the second most common neurodegenerative disorder, is characterized by the progressive loss of dopaminergic neurons in the substantia nigra pars compacta, leading to motor and ...
    • Bioelectric stimulation outperforms brain derived neurotrophic factor in promoting neuronal maturation 

      Diego Santiago , María del Pilar; González, María Ujué; Zamora Sánchez, Esther María; Cortés Carrillo, Núria; Dotti, Carlos; Guix Rafols, Francesc Xavier; Mobini, Sahba (Scientific Reports 2025, 15, 2025-02)
      Neuronal differentiation and maturation are crucial for developing research models and therapeutic applications. Brain-derived neurotrophic factor (BDNF) is a widely used biochemical stimulus for promoting ...
    • BrainBike peptidomimetic enables efficient transport of proteins across brain endothelium 

      Lucana, Maria C.; Lucchi, Roberta; Gosselet, Fabien; Díaz-Perlas, Cristina; Oller-Salvia, Benjamí (RSC Chemical Biology. 2024;5(1):7-11, 2023-12-11)
      Protein therapeutics cannot reach the brain in sufficient amounts because of their low permeability across the blood–brain barrier. Here we report a new family of bicyclic peptide shuttles, BrainBikes, ...
    • A practical guide to computational tools for engineering biocatalytic properties 

      Vega, Aitor; Planas, Antoni; Biarnés, Xevi (International Journal of Molecular Sciences 2025, 26(3), 980, 2025-02-01)
      The growing demand for efficient, selective, and stable enzymes has fueled advancements in computational enzyme engineering, a field that complements experimental methods to accelerate enzyme discovery. ...
    • A scoping review on mycotoxin-induced neurotoxicity 

      Abia, Wilfred; Foupouapouognigni, Yacouba; NFOMBOUOT NJITOYAP, Herman Philipe; Viviane Laure, Ngoungoure ndam; Epole, Ntungwe; Ben Salah-ABBES, Jalila; TCHANA NKOUATCHOUA, ANGELE (Discover Toxicology 2025, 2 (1), 2025-12)
      Mycotoxins are toxic secondary metabolites produced by toxigenic fungi. Acute and chronic dietary exposure to toxigenic mycotoxins can cause various adverse health effects in humans and animals and thus ...
    • A Site-Specific MiniAp4–Trastuzumab Conjugate Prevents Brain Metastasis 

      Al-Masmudi Martín, Mariam; Oller-Salvia, Benjamí; Perea Villena, María Jesús; teixido, meritxell; Valiente, Manuel; giralt, ernest; Sanchez-Navarro, Macarena (Molecular Pharmaceutics 2025, 22, 3, 1384–1395, 2025-03-03)
      Monoclonal antibodies (mAbs) are changing cancer treatments. However, the presence of the blood–brain barrier (BBB) and the blood–tumor barrier (BTB) limits the use of mAbs to treat brain cancer or brain ...