Ara mostrant els elements 61-80 de 256

    • Teaching Cheminformatics through a Collaborative Intercollegiate Online Chemistry Course (OLCC) 

      Kim, Sunghwan; Bucholtz, Ehren; Briney, Kristin; Cornell, Andrew; Cuadros, Jordi; Fulfer, Kristen; Gupta, Tanya; Hepler-Smith, Evan; Johnston, Dean; Lang, Andrew; Larsen, Delmar; Li, Ye; McEwen, Leah; Morsch, Layne; Muzyka, Jennifer; Belford, Robert (Journal of Chemical Education, 2020-12-21)
      While cheminformatics skills necessary for dealing with an ever-increasing amount of chemical information are considered important for students pursuing STEM careers in the age of big data, many schools ...
    • Androgenic activation, impairment of the monoaminergic system and altered behavior in zebrafish larvae exposed to environmental concentrations of fenitrothion 

      Faria, Melissa; Prats, Eva; Rosas Ramírez, Jonathan Ricardo; Bellot, Marina; Bedrossiantz, Juliette; Pagano, Maria; Valls, Arnau; Gómez Canela, Cristian; Porta, Josep M; Mestres, Jordi; Garcia-Reyero, Natàlia; Faggio, Caterina; Gómez-Oliván, Leobardo Manuel; Raldua, Demetrio (Science of the Total Environment, 2021-06-25)
      Fenitrothion is an organophosphorus insecticide usually found in aquatic ecosystems at concentrations in the range of low ng/L. In this manuscript we show that 24 h exposure to environmental concentrations ...
    • The impact of the perceived risk of COVID-19 on consumers' attitude and behavior toward locally produced food 

      Palau i Saumell, Ramon; Matute, Jorge; Derqui, Belén; Meyer, Jan-Hinrich (British Food Journal, 2021-12-17)
      Purpose This study analyzes the impact of the COVID-19 pandemic on the consumption of locally produced food. In particular, it examines an extended model of the theory of planned behavior, with the ...
    • Targeting transthyretin in Alzheimer's disease: Drug discovery of small-molecule chaperones as disease-modifying drug candidates for Alzheimer's disease 

      Planas, Antoni (Planas Sauter); Cotrina, Ellen Y.; Santos, Luis Miguel; Rivas, Josep; Blasi, Daniel; Leite, José Pedro; Liz, Márcia A.; Busquets, Maria Antònia; Prohens, Rafel; Gimeno, Ana; Jiménez-Barbero, Jesús; Gales, Luis; Llop, Jordi; Quintana, Jordi; Cardoso, Isabel; Arsequell, Gemma (European Journal of Medicinal Chemistry, 2021-12-15)
      Transthyretin (TTR) has a well-established role in neuroprotection in Alzheimer's Disease (AD). We have setup a drug discovery program of small-molecule compounds that act as chaperones enhancing ...
    • High-efficacy subcellular micropatterning of proteins using fibrinogen anchors 

      Watson, Joseph; Aich, Samya; Oller Salvia, Benjamí; Drabek, Andrew A.; Blacklow, Stephen; Chin, Jason; Derivery, Emmanuel (Journal of Cell Biology, 2021-01-08)
      Protein micropatterning allows proteins to be precisely deposited onto a substrate of choice and is now routinely used in cell biology and in vitro reconstitution. However, drawbacks of current technology ...
    • Prospects on coupling UV/H2O2 with activated sludge or a fungal treatment for the removal of pharmaceutically active compounds in real hospital wastewater 

      Mir Tutusaus, Josep Anton; Jaén-Gil, Adrián; Barceló, Damià; Buttiglieri, Gianluigi; González Olmos, Rafael; Rodriguez Mozaz, Sara; Caminal, Gloria; Sarrà, Montserrat (Science of the Total Environment, 2021-06-15)
      Conventional active sludge (AS) process at municipal centralized wastewater treatment facilities may exhibit little pharmaceuticals (PhACs) removal efficiencies when treating hospital wastewater (HWW). ...
    • Combining biological processes with UV/H2O2 for metoprolol and metoprolol acid removal in hospital wastewater 

      Jaén-Gil, Adrián; Buttiglieri, Gianluigi; Benito, Aleix; Mir Tutusaus, Josep Anton; González Olmos, Rafael; Caminal, Gloria; Barceló, Damià; Sarrà, Montserrat; Rodriguez-Mozaz, Sara (Chemical Engineering Journal, 2021-01-15)
      The transformation products (TPs) of water contaminants generated during wastewater treatment can sometimes be equally or even more hazardous than the parent compounds. Therefore, for a comprehensive ...
    • Role of amino terminal substitutions in the pharmacological, rewarding and psychostimulant profiles of novel synthetic cathinones 

      Duart-Castells, L.; Nadal Gratacós, Núria; Muralter, M.; Puster, B.; Berzosa Rodríguez, Xavier; Estrada Tejedor, Roger; Niello, M.; Bhat, S.; Pubill Sánchez, David; Camarasa, J.; Sitte, H. H.; Escubedo, E.; López-Arnau, R. (Neuropharmacology, 2021-03-15)
      The emergence of new synthetic cathinones continues to be a matter of public health concern. In fact, they are quickly replaced by new structurally related alternatives. The main goal of the present ...
    • Zwitterionic self-assembled nanoparticles as carriers for Plasmodium targeting in malaria oral treatment 

      Biosca, Arnau; Cabanach Xifró, Pol; Abdulkarim, Muthanna; Gumbleton, Mark; Gómez Canela, Cristian; ramírez moreno, miriam; Bouzón-Arnáiz, Inés; Avalos-Padilla, Yunuen; Borrós i Gómez, Salvador; Fernàndez-Busquets, Xavier (Journal of Controlled Release. Vol.331, p.364-375, 2021-03-10)
      The current decline in antimalarial drug efficacy due to the evolution of resistant Plasmodium strains calls for new strategies capable of improving the bioavailability of antimalarials, especially of ...
    • Plasmodium falciparum apicomplexan-specific glucosamine-6-phosphate n-acetyltransferase is key for amino sugar metabolism and asexual blood stage development 

      Planas, Antoni (Planas Sauter); Leivar Rico, Pablo; Chi, Jordi; Cova, Marta; De las Rivas, Matilde; Medina, Ana; Junqueira Borges, Rafael; Usón, Isabel; Hurtado-Guerrero, Ramón; Izquierdo, Luis (Molecular Biology and Physiology. Vol.11, n.5 (2020), e02045-20, 2020-10)
      ABSTRACT UDP-N-acetylglucosamine (UDP-GlcNAc), the main product of the hexosamine biosynthetic pathway, is an important metabolite in protozoan parasites since its sugar moiety is incorporated into ...
    • A consistent thermodynamic molecular model of n-hydrofluoroolefins and blends for refrigeration applications 

      Llovell Ferret, Félix Lluís; Albà, Carlos G.; Vega, Lourdes F. (International Journal of Refrigeration. Vol.113 (2020), p.145-155, 2020-05)
      This work presents a thermodynamic model that characterizes 4th-generation hydrofluoroolefins (HFOs)-based refrigerants with the molecular-based soft-SAFT equation of state (Blas and Vega, 1998) as well ...
    • Porficenos para la fotoquimioterapia del cáncer y otras aplicaciones biomédicas 

      Nonell, Santi; Sánchez García, David; Borrell Bilbao, José Ignacio; Teixidó i Closa, Jordi; Arad, Ofir; Gavaldá, Ana; Rey, Óscar; Rubio, Noemi; Cañete, Magdalena; Juarranz, Angeles; Villanueva, Angeles; Stockert, Juan C.; Díaz Jiménez, Pablo J. (Afinidad. Vol.59, n.500 (2002), p.343-356, 2002)
      La terapia fotodinámica (PDT) o fotoquimioterapia del cáncer es una modalidad terapéutica que consiste en la aplicación de compuestos fotosensibilizadores que se acumulan preferentemente en tejidos ...
    • Glycosidases and glycosynthases in enzymatic synthesis of oligosaccharides: an overview 

      Planas, Antoni (Planas Sauter); Faijes, Magda (Afinidad. Vol.59, n.500 (2002), p.295-313, 2002)
      Retaining glycosidases have been extensively studied for the synthesis of oligosaccharides and glycoconjugates as a convenient enzymatic approach to achieve the required regio- and stereoselectivity in ...
    • The role of carbon black surface activity and specific surface area in the vulcanization reaction 

      Borrós i Gómez, Salvador; Tricás, N.; Vidal-Escales, E. (Afinidad. Vol.59, n.500 (2002), p.337-342, 2002)
      This paper reviews the work developed in studying how Carbon Black presence may affect the vulcanization process and the mechanisms by which CB and polymer interact, which has not been completely described ...
    • Heteroacoplamientos catalizados por paladio 

      Teixidó i Closa, Jordi; Sánchez García, David; Borrós i Gómez, Salvador; Nonell, Santi; Borrell Bilbao, José Ignacio; Colominas Guàrdia, Carles (Afinidad. Vol.59, n.500 (2002), p.325-336, 2002)
      Durante los diez últimos años la química del paladio se ha aplicado intensamente en síntesis orgánica debido a su versatilidad y a su gran selectividad. En esta breve revisión se muestran las características ...
    • Introducción a la química combinatoria 

      Borrell Bilbao, José Ignacio; Teixidó i Closa, Jordi; Falcó, José Luis; Pascual, Rosalía (Afinidad. Vol.59, n.500 (2002), p.314-324, 2002)
      Durante los últimos diez años la Química Combinatoria se ha convertido en una técnica usual para el descubrimiento y desarrollo de nuevos productos con actividad biológica. El presente minireview pretende ...
    • Preparation and applications of organo-silica hybrid mesoporous silica nanoparticles for the co-delivery of drugs and nucleic acids 

      Sánchez García, David; Pontón, Iris; Martí del Rio, Andrea; Gómez Gómez, Marta (Nanomaterials. Vol.10, n.12 (2020), 2466, 2020-12)
      Combination therapies rely on the administration of more than one drug, with independent mechanisms of action, aiming to enhance the efficiency of the treatment. For an optimal performance, the ...
    • Therapeutic potential of N-acetylcysteine in acrylamide acute neurotoxicity in adult zebrafish 

      Gómez Canela, Cristian; Faria, Melissa; Prats, Eva; Hsu, Chuan-Yu; Arick, Mark A. II; Bedrossiantz, Juliette; Orozco, Manuel; Garcia-Reyero, Natàlia; Ziv, Tamar; Ben-Lulu, Shani; Admon, Arie; Gómez-Oliván, Leonardo Manuel; Raldúa, Demetrio (Scientific Reports. Vol.9, n.1 (2019), 16467, 2019-11)
      Two essential key events in acrylamide (ACR) acute neurotoxicity are the formation of adducts with nucleophilic sulfhydryl groups on cysteine residues of selected proteins in the synaptic terminals and ...
    • Un modèle épistémologique de référence pour la recherche sur l’algèbre élémentaire 

      Bosch, Marianna; Ruiz-Munzón, Noemí; Gascón, Josep (Nouveaux cahiers de la recherche en éducation. Vol.22, n.1 (2020), p.123–144, 2020-06)
      La théorie anthropologique du didactique attribue un rôle déterminant au questionnement du savoir mathématique et propose comme outil d’analyse l’élaboration de modèles épistémologiques de référence ...
    • Serotype-specific detection of dengue viruses in a nonstructural protein 1-based enzyme-linked immunosorbent assay validated with a multinational cohort 

      Fandos, Diana; Bosch, Irene; Reddy, Ankita; De Puig, Helena; Ludert, Juan E.; Perdomo-Celis, Federico; Narváez, Calos F.; Versiani, Alice; Nogueira, Mauricio L.; Singla, Mohit; Lodha, Rakesh; Medigeshi, Guruprasad R.; Lorenzana, Ivette; Ralde, Hugo Vicente; Gelvez-Ramirez, Margarita; Villar, Luis A.; Hiley, Megan; Mendoza, Laura; Salcedo, Nol; Herrera, Bobby Brooke; Gehrke, Lee (PLoS Neglected Tropical Diseases. Vol. 14, n.6 (2020), e0008203, 2020-06)
      Background Dengue virus (DENV) infections pose one of the largest global barriers to human health. The four serotypes (DENV 1–4) present different symptoms and influence immune response to subsequent ...