Listando Articles publicats en revistes por materia "616"
Mostrando ítems 1-14 de 14
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Activity of the novel BCR kinase inhibitor IQS019 in preclinical models of B-cell non-Hodgkin lymphoma
(Journal of Hematology & Oncology. Vol.10, n.80 (2017), 2017-03)Background Pharmacological inhibition of B cell receptor (BCR) signaling has recently emerged as an effective approach in a wide range of B lymphoid neoplasms. However, despite promising clinical activity ... -
Erlotinib Promotes Ligand-Induced EGFR Degradation in 3D but Not 2D Cultures of Pancreatic Ductal Adenocarcinoma Cells
(Cancers, 2021-09-07)The epithelial growth factor receptor (EGFR) is a tyrosine kinase receptor that participates in many biological processes such as cell proliferation. In addition, EGFR is overexpressed in many epithelial ... -
Extracellular vesicles and their current role in cancer immunotherapy
(Cancers, 2021-05-10)Extracellular vesicles (EVs) are natural particles formed by the lipid bilayer and released from almost all cell types to the extracellular environment both under physiological conditions and in presence ... -
Glycyrrhetinic acid-functionalized mesoporous silica nanoparticles for the co-delivery of DOX/CPT-PEG for targeting HepG2 cells
(Pharmaceutics. Vol.12, n.11 (2020), 1048, 2020-11)A pH-triggered mesoporous silica nanoparticle (MSN)-based nano-vehicle for the dual delivery of doxorubicin (DOX)/camptothecin-PEG (CPT-PEG) has been prepared. To enhance its selectivity, the nanoparticles ... -
Nanomedicine in non-small cell lung cancer: from conventional treatments to immunotherapy
(Cancers. Vol.12, n.6 (2020), 1609, 2020-06)Non-small cell lung cancer (NSCLC) remains the most common cause of cancer-related mortality. The heterogeneous nature of this disease hinders its diagnosis and treatment, requiring continuous advances ... -
Oligopeptide-modified poly(beta-amino ester)s-coated AdNuPARmE1A: boosting the efficacy of intravenously administered therapeutic adenoviruses
(Theranostics. Vol.10, n.6 (2020), p. 2744-2758, 2020-02)Oncolytic adenoviruses are used as agents for the treatment of cancer. However, their potential is limited due to the high seroprevalence of anti-adenovirus neutralizing antibodies (nAbs) within the ... -
Photodynamic synergistic effect of pheophorbide a and doxorubicin in combined treatment against tumoral cells
(Cancers. Vol.9, n.2 (2017), 18, 2017-02)A combination of therapies to treat cancer malignancies is at the forefront of research with the aim to reduce drug doses (ultimately side effects) and diminish the possibility of resistance emergence ... -
Porficenos para la fotoquimioterapia del cáncer y otras aplicaciones biomédicas
(Afinidad. Vol.59, n.500 (2002), p.343-356, 2002)La terapia fotodinámica (PDT) o fotoquimioterapia del cáncer es una modalidad terapéutica que consiste en la aplicación de compuestos fotosensibilizadores que se acumulan preferentemente en tejidos ... -
Serotype-specific detection of dengue viruses in a nonstructural protein 1-based enzyme-linked immunosorbent assay validated with a multinational cohort
(PLoS Neglected Tropical Diseases. Vol. 14, n.6 (2020), e0008203, 2020-06)Background Dengue virus (DENV) infections pose one of the largest global barriers to human health. The four serotypes (DENV 1–4) present different symptoms and influence immune response to subsequent ... -
Syndecans and Pancreatic Ductal Adenocarcinoma
(Biomolecules, 2021-02-25)Pancreatic Ductal Adenocarcinoma (PDAC) is a fatal disease with poor prognosis because patients rarely express symptoms in initial stages, which prevents early detection and diagnosis. Syndecans, a ... -
The Masking Game: Design of Activatable Antibodies and Mimetics for Selective Therapeutics and Cell Control
(ACS Central Science, 2021-04-26)The high selectivity and affinity of antibody binding havemade antibodies all-pervasive tools in therapy, diagnosis, and basic science.A plethora of chemogenetic approaches has been devised to makeantibodies ... -
Three-dimensional tumor-stroma co-culture system development using self-assembling peptide scaffolds
(Afinidad. Vol.76, n.587 (2019), p.163-170, 2019-07)Cancer research has traditionally relied on 2D cell culture, focusing mainly on cancer cells and its disrupted genetics. However, tumors have been accepted as complex tissues, and as such, they need ... -
Unraveling the effects of the COVID‐19 pandemic on the hospital burden of respiratory syncytial virus
(Pediatric Pulmonology, 2023-07-26) -
Zwitterionic 3D-printed non-immunogenic stealth microrobots
(Advanced Materials. Vol.32, n.42 (2020), 2003013, 2020-08)Microrobots offer transformative solutions for non-invasive medical interventions due to their small size and untethered operation inside the human body. However, they must face the immune system as a ...