Now showing items 126-145 of 256

    • Glycyrrhetinic acid-functionalized mesoporous silica nanoparticles for the co-delivery of DOX/CPT-PEG for targeting HepG2 cells 

      Sánchez García, David; Borrós i Gómez, Salvador; Fornaguera Puigvert, Cristina; Martínez Edo, Gabriel (Pharmaceutics. Vol.12, n.11 (2020), 1048, 2020-11)
      A pH-triggered mesoporous silica nanoparticle (MSN)-based nano-vehicle for the dual delivery of doxorubicin (DOX)/camptothecin-PEG (CPT-PEG) has been prepared. To enhance its selectivity, the nanoparticles ...
    • Glyphosate targets fish monoaminergic systems leading to oxidative stress and anxiety 

      Faria, Melissa; Bedrossiantz, Juliette; Rosas Ramírez, Jonathan Ricardo; Mayol, Marta; Heredia García, Gerardo; Bellot, Marina; Prats, Eva; Garcia-Reyero, Natàlia; Gómez Canela, Cristian; Gómez-Oliván, Leobardo Manuel; Raldua, Demetrio (Environment International, 2020-11-18)
      Glyphosate is the active ingredient of some of the most highly produced and used herbicides worldwide. The intensive applications of glyphosate-based herbicides and its half-life in water lead to its ...
    • Heteroacoplamientos catalizados por paladio 

      Teixidó i Closa, Jordi; Sánchez García, David; Borrós i Gómez, Salvador; Nonell, Santi; Borrell Bilbao, José Ignacio; Colominas Guàrdia, Carles (Afinidad. Vol.59, n.500 (2002), p.325-336, 2002)
      Durante los diez últimos años la química del paladio se ha aplicado intensamente en síntesis orgánica debido a su versatilidad y a su gran selectividad. En esta breve revisión se muestran las características ...
    • High photostability in nonconventional coumarins with far-red/NIR emission through azetidinyl substitution 

      Nonell, Santi; Bresolí Obach, Roger; Gandioso, Albert; Palau Requena, Marta; Galindo Muñoz, Alex; Rovira, Anna; Bosch, Manel; Marchán Sancho, Vicente (Journal of Organic Chemistry. Vol.83, n.19 (2018), p.11519-11531, 2018-08)
      Replacement of electron-donating N,N-dialkyl groups with three- or four-membered cyclic amines (e.g., aziridine and azetidine, respectively) has been described as a promising approach to improve some ...
    • High-efficacy subcellular micropatterning of proteins using fibrinogen anchors 

      Watson, Joseph; Aich, Samya; Oller Salvia, Benjamí; Drabek, Andrew A.; Blacklow, Stephen; Chin, Jason; Derivery, Emmanuel (Journal of Cell Biology, 2021-01-08)
      Protein micropatterning allows proteins to be precisely deposited onto a substrate of choice and is now routinely used in cell biology and in vitro reconstitution. However, drawbacks of current technology ...
    • Identificación de las principales competencias necesarias para el uso profesional de la estadística aplicada en ADE 

      Serrano Molinero, Vanessa; González Sabaté, Lucinio (Revista del Congrés Internacional de Docència Universitària i Innovació, núm.2 (2014), 2014)
      El objetivo de este trabajo es determinar las competencias para el uso profesional de la Estadística que son más valoradas para optar a un puesto de trabajo. Para ello se ha utilizado una metodología ...
    • Impact of low stocking densities shrimp farm effluents in water quality of a tropical coastal wetland 

      Nomen i Ribé, Rosa; Sempere Cebrian, Julià; Rovira, M.D.; de López, N.A. (Afinidad. Vol.77, n.589 (2020), p.53-62, 2020-03)
      The effects of shrimp aquaculture on the water quality of the Jiquilisco Bay (El Salvador) was evaluated for small-scale shrimp farming with low stocking densities (≤ 12 shrimps/m2). Two sites were ...
    • In silico discovery of substituted pyrido[2,3-d]pyrimidines and pentamidine-like compounds with biological activity in myotonic dystrophy models 

      Estrada Tejedor, Roger; Borrell Bilbao, José Ignacio; Teixidó i Closa, Jordi; González, Àlex L.; Konieczn, Piotr; Llamusi, Beatriz; Delgado-Pinar, Estefanía; García-España, Enrique; Pérez-Alonso, Manuel; Artero, Rubén (PLoS ONE. Vol.12, n.6 (2017), e0178931, 2017-06)
      Myotonic dystrophy type 1 (DM1) is a rare multisystemic disorder associated with an expansion of CUG repeats in mutant DMPK (dystrophia myotonica protein kinase) transcripts; the main effect of these ...
    • In the opinion of scientists: are there rules in research? Pilot study on the most widespread rules of scientific research 

      de la Lama Zubirán, Paula; De la Lama García, Alfredo; del Castillo Mussot, Marcelo (2021-01-31)
      Sociologists, ethnologists, philosophers among others have tried to identify the norms or rules that govern scientific research; however, so far, they have not been widely accepted by scientists. This ...
    • Industria farmacéutica 4.0 

      Sempere Cebrián, Julià; Nomen i Ribé, Rosa (Pharmatech. N.42 (marzo-abril 2019), p.79-82, 2019-03)
      La implantación de las tecnologías de la industria 4.0 va a producir grandes cambios en la industria química y farmacéutica. Disponer de un modelo claro de lo qué es la industria 4.0 es clave para ...
    • Influence of building orientation on the flexural strength of laminated object manufacturing specimens 

      Borrós i Gómez, Salvador; Reyes Pozo, Guillermo; Olivier, Djamila; Travieso Rodriguez, Jose Antonio; Jerez Mesa, Ramón (Journal of Mechanical Science and Technology. Vol. 31, no.1 (2017), p.133-139, 2017-01)
      This study aims to define the best building orientation for components produced via the Laminated object manufacturing (LOM) technique to enhance their flexural performance. Results of previous research ...
    • Influence of the carbon incorporation on the mechanical properties of TiB2 thin films prepared by HiPIMS 

      Sala, N.; Abad, Manuel David; Sánchez-López, J.C.; Crugeira, F.; Ramos-Masana, A.; Colominas, Carles (International Journal of Refractory Metals and Hard Materials. Vol.107 (2022), 105884, 2022-09)
      Nanostructured TiB2 and TiBC thin films with carbon contents up to 11 at. % were prepared by physical vapor deposition using high power impulse magnetron sputtering (HiPIMS) technology. The influence ...
    • Inquiry based mathematics education and the development of learning trajectories 

      Bosch, Marianna; Artigue, Michèle; Doorman, Michiel; Juhász, Péter; Kvasz, Ladislav; Maass, Katja (Teaching Mathematics and Computer Science. Vol.18, n.3 (2020) p.63-89, 2020)
      This article is based on the panel on inquiry based mathematics education and the development of learning trajectories held at the VARGA 100 Conference. After an introduction presenting the theme and ...
    • Introducción a la química combinatoria 

      Borrell Bilbao, José Ignacio; Teixidó i Closa, Jordi; Falcó, José Luis; Pascual, Rosalía (Afinidad. Vol.59, n.500 (2002), p.314-324, 2002)
      Durante los últimos diez años la Química Combinatoria se ha convertido en una técnica usual para el descubrimiento y desarrollo de nuevos productos con actividad biológica. El presente minireview pretende ...
    • La llavor del Papa Francesc: Aparecida (Brasil), 2007 

      Sols Lucia, José (Ars Brevis, 2016, Núm. 22, p. 256-269, 2016)
      Analitzar el document final de la V Conferència General de l’Episcopat Llatinoamericà i del Carib, celebrada a Aparecida, Brasil, fa deu anys, el 2007, resulta avui especialment interessant, ja que el ...
    • Las oportunidades de negocio ¿se reconocen o se construyen? 

      Olivé Tomàs, Antoni (Estudios Empresariales. Número 141(2013), p. 62-70, 2013)
      En este artículo se trata de dar respuesta a la pregunta de si las oportunidades de negocio ya existían antes de reconocerse y se reconocen simplemente o si deben construirse desde cero. El autor también ...
    • Las predicciones científicas de D.I. Mendeleiev 

      Victori, L.; Llinàs, J. M. (Afinidad. Vol.65, n.533 (2008), p.7-10, 2008-01)
      Este trabajo estudia las predicciones de Mendeleiev sobrela posible equivalencia entre materia y energía. Al mis-mo tiempo hace una crítica de algunos comentarios sobreeste punto aparecidos en la ...
    • Leading edge technologies in wastewater treatment 

      González Olmos, Rafael (AIMS Environmental Science. Vol.2, n.2 (2015), p.237-240, 2015-04)
    • Learning by doing? Partners audit experience and the quality of audit services 

      García Blandón, Josep; Argilés Bosch, Josep M.; Ravenda, Diego (Revista de Contabilidad: Spanish Accounting Review. Vol. 23, n. 2 (2020), pág. 197-209, 2020-07)
      A pesar de la evidencia que sugiere que el conocimiento especializado debería resultar más relevante que el genérico para explicar diferentes niveles de calidad de auditoría asociados a los auditores ...
    • Mandatory IFRS adoption and the cost of equity capital: Evidence from Spanish firms 

      Castillo Merino, David; Menéndez Plans, Carlota; Orgaz Guerrero, Neus (Intangible Capital (2014) vol. 10, n.3, p. 562-583, 2014-06-26)
      Purpose: The main objective of this paper analyses the effects of mandatory International Financial Reporting Standards (IFRS) adoption by Spanish firms in 2005 on the cost of equity capital. ...