IQS: Recent submissions
Now showing items 81-100 of 317
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Heteroacoplamientos catalizados por paladio
(Afinidad. Vol.59, n.500 (2002), p.325-336, 2002)Durante los diez últimos años la química del paladio se ha aplicado intensamente en síntesis orgánica debido a su versatilidad y a su gran selectividad. En esta breve revisión se muestran las características ... -
Introducción a la química combinatoria
(Afinidad. Vol.59, n.500 (2002), p.314-324, 2002)Durante los últimos diez años la Química Combinatoria se ha convertido en una técnica usual para el descubrimiento y desarrollo de nuevos productos con actividad biológica. El presente minireview pretende ... -
Preparation and applications of organo-silica hybrid mesoporous silica nanoparticles for the co-delivery of drugs and nucleic acids
(Nanomaterials. Vol.10, n.12 (2020), 2466, 2020-12)Combination therapies rely on the administration of more than one drug, with independent mechanisms of action, aiming to enhance the efficiency of the treatment. For an optimal performance, the ... -
Therapeutic potential of N-acetylcysteine in acrylamide acute neurotoxicity in adult zebrafish
(Scientific Reports. Vol.9, n.1 (2019), 16467, 2019-11)Two essential key events in acrylamide (ACR) acute neurotoxicity are the formation of adducts with nucleophilic sulfhydryl groups on cysteine residues of selected proteins in the synaptic terminals and ... -
Un modèle épistémologique de référence pour la recherche sur l’algèbre élémentaire
(Nouveaux cahiers de la recherche en éducation. Vol.22, n.1 (2020), p.123–144, 2020-06)La théorie anthropologique du didactique attribue un rôle déterminant au questionnement du savoir mathématique et propose comme outil d’analyse l’élaboration de modèles épistémologiques de référence ... -
Serotype-specific detection of dengue viruses in a nonstructural protein 1-based enzyme-linked immunosorbent assay validated with a multinational cohort
(PLoS Neglected Tropical Diseases. Vol. 14, n.6 (2020), e0008203, 2020-06)Background Dengue virus (DENV) infections pose one of the largest global barriers to human health. The four serotypes (DENV 1–4) present different symptoms and influence immune response to subsequent ... -
The potential of proteolytic chimeras as pharmalogical tools and therapeutic agents
(Molecules. Vol.25, n.24 (2020), 5956, 2020-12)The induction of protein degradation in a highly selective and efficient way by means of druggable molecules is known as targeted protein degradation (TPD). TPD emerged in the literature as a revolutionary ... -
Role of infill parameters on the mechanical performance and weight reduction of PEI Ultem processed by FFF
(Material & Design. Vol. 193 (2020), 108810, 2020-08)In comparison with conventional manufacturing technologies, Fused Filament Fabrication (FFF) offers countless benefits. It broadens the horizons of the design of structural components with high geometrical ... -
Preparative scale production of recombinant human transthyretin for biophysical studies of protein-ligand and protein-protein interactions
(International Journal of Molecular Sciences. Vol.21, n.24 (2020), 9640, 2020-12)Human transthyretin (hTTR), a serum protein with a main role in transporting thyroid hormones and retinol through binding to the retinol-binding protein, is an amyloidogenic protein involved in familial ... -
Zwitterionic 3D-printed non-immunogenic stealth microrobots
(Advanced Materials. Vol.32, n.42 (2020), 2003013, 2020-08)Microrobots offer transformative solutions for non-invasive medical interventions due to their small size and untethered operation inside the human body. However, they must face the immune system as a ... -
Screening of ionic liquids and deep eutectic solvents for physical CO2 absorption by soft-SAFT using key performance indicators
(Journal of Chemical and Engineering Data. Vol. 65, n.12 (2020), p.5844-5861, 2020-10)The efficient screening of solvents for CO2 capture requires a reliable and robust equation of state to characterize and compare their thermophysical behavior for the desired application. In this work, ... -
Relationship between marital status and incidence of type 2 diabetes mellitus in a Brazilian rural population: the Baependi heart study
(PLoS One. Vol. 15, n.8 (2020), e0236869, 2020-08)Many factors influence the incidence of type 2 diabetes mellitus (T2DM). Here, we investigated the associations between socio-demographic characteristics and familial history with the 5-year incidence ... -
Stochastic modeling reveals kinetic heterogeneity in post-replication DNA methylation
(PLoS Computational Biology. Vol. 16, n.4 (2020), e1007195, 2020-04)DNA methylation is a heritable epigenetic modification that plays an essential role in mammalian development. Genomic methylation patterns are dynamically maintained, with DNA methyltransferases mediating ... -
Triglyceride glucose index as a tool to motivate early lifestyle modification in young adults at diabetes risk: the baependi heart study
(Preventive medicine reports. Vol.20 (2020), 101172, 2020-12)Considering that the incidence of type 2 diabetes mellitus (T2DM) has been increasing especially in developing countries and becoming a global public health problem, this study aims to evaluate the ... -
Do folate-receptor targeted liposomal photosensitizers enhance photodynamic therapy selectivity?
(Biochimica et Biophysica Acta (BBA) -Biomembranes. Vol.1808, n.4 (2011), p.1063-1071, 2011-01)One of the current goals in photodynamic therapy research is to enhance the selective targeting of tumor cells in order to minimize the risk and the extension of unwanted side-effects caused by normal ... -
Conjugated polymers: synthesis and applications in optoelectronics
(Afinidad. Vol.71, n.568 (2014), p.251-262, 2014-10)In the last 50 years the development of conjugated polymers for applications in optoelectronics and energy has attracted great interest because of its use as conductive polymers, in solar cells or ... -
Tetramethylbenzidine: an acoustogenic photoacoustic probe for reactive oxygen species detection
(Sensors. Vol.20, n.20 (2020), 5952, 2020-10)Photoacoustic imaging is attracting a great deal of interest owing to its distinct advantages over other imaging techniques such as fluorescence or magnetic resonance image. The availability of photoacoustic ... -
Quintuple helix and innovation on performance of SMEs within ability of SMEs as a mediator variable: a comparative study of creative industry in Indonesia and Spain
(Management Science Letters. Vol. 10, n.6 (2020), p.1389-1400, 2020)The purpose of this study is to analyse the effects of (1) quintuple helix on small and medium enterprises (SMEs) performance; (2) ability of SMEs on SMEs performance; (3) quintuple helix on ability of ... -
Smart dual-functionalized gold nanoclusters for spatio-temporally controlled delivery of combined chemo- and photodynamic therapy
(Nanomaterials. Vol.10, n.12 (2020), 2474, 2020-12)We report the preparation of gold nanoclusters (AuNCs) as a delivery vehicle for the clinically approved photodynamic and chemotherapeutic agents Protoporphyrin IX (PpIX) and doxorubicin (DOX), respectively, ... -
New developments in vertebroplasty materials
(Afinidad. Vol.75, n.583 (2018), p.165-174, 2018-07)Increasing life expectancy is leading to an increase in age-related diseases, like osteoporosis, which often involve the breakdown of bone. One of the main problems related with such disease is the ...