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Simple generation of human induced pluripotent stem cells using poly-β-amino esters as the non-viral gene delivery system
(The American Society for Biochemistry and Molecular Biology, 2011-04)
Reprogramming of somatic cells to induced pluripotent stem (iPS) cells can be achieved by the delivery of a combination of transcription factors, including Oct4, Sox2, Klf4, and c-Myc. Retroviral and ...
Understanding optical trapping phenomena: a simulation for undergraduates
(Institute of Electrical and Electronics Engineers (IEEE), 2011-02)
Optical trapping is an attractive and multidisciplinary topic that has become the center of attention to a large number of researchers. Moreover, it is a suitable subject for advanced students that ...
The interaction effects of firm and partner tenure on audit quality
(Taylor and Francis, 2017-02)
This paper investigates the impact of firm and partner tenure on audit quality, where audit quality is proxied by discretionary accruals. We study a sample of Spanish listed companies between 2005 and ...
Una nova taula periòdica per a l'ensenyament secundari
(Institut d'Estudis Catalans, 2015)
Characterization of duplex coating system (HVOF + PVD) on light alloy substrates
(Elsevier, 2017-05)
Light metals such as aluminium or magnesium alloys play an important role in many different industrial applications. However, aluminium and especially magnesium alloys show relatively poor resistance ...
Zwitterionic self-assembled nanoparticles as carriers for Plasmodium targeting in malaria oral treatment
(Elsevier, 2021-03-10)
The current decline in antimalarial drug efficacy due to the evolution of resistant Plasmodium strains calls for new strategies capable of improving the bioavailability of antimalarials, especially of ...
Therapeutic potential of N-acetylcysteine in acrylamide acute neurotoxicity in adult zebrafish
(Nature Research, 2019-11)
Two essential key events in acrylamide (ACR) acute neurotoxicity are the formation of adducts with nucleophilic sulfhydryl groups on cysteine residues of selected proteins in the synaptic terminals and ...
Epithelial to mesenchymal transition in human endocrine islet cells
(PLoS (Public Library of Science), 2018-01)
Background
β-cells undergo an epithelial to mesenchymal transition (EMT) when expanded in monolayer culture and give rise to highly proliferative mesenchymal cells that retain the potential to ...
Nanomedicine in non-small cell lung cancer: from conventional treatments to immunotherapy
(MDPI, 2020-06)
Non-small cell lung cancer (NSCLC) remains the most common cause of cancer-related mortality. The heterogeneous nature of this disease hinders its diagnosis and treatment, requiring continuous advances ...
An Assessment of mandatory audit firm rotation and limitation of non-audit services imposed by the Regulation (EU) No 537/2014: Evidence from Spain
(Elsevier, 2017-09)
On May 27, 2014, Regulation (EU) No 537/2014 was published in the Official Journal of the European Union. Aiming to enhance audit quality, the new regulation establishes, among other measures, a maximum ...