Visualitzant IQS per matèria "539"
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Detection of peptide-based nanoparticles in blood plasma by ELISA
(PLoS ONE. Vol.10, n.5 (2015), e0126136, 2015-05)Aims The aim of the current study was to develop a method to detect peptide-linked nanoparticles in blood plasma. Materials & Methods A convenient enzyme linked immunosorbent assay (ELISA) was developed ... -
Glycyrrhetinic acid-functionalized mesoporous silica nanoparticles for the co-delivery of DOX/CPT-PEG for targeting HepG2 cells
(Pharmaceutics. Vol.12, n.11 (2020), 1048, 2020-11)A pH-triggered mesoporous silica nanoparticle (MSN)-based nano-vehicle for the dual delivery of doxorubicin (DOX)/camptothecin-PEG (CPT-PEG) has been prepared. To enhance its selectivity, the nanoparticles ... -
PEI-mediated transient transfection of high five cells at bioreactor scale for HIV-1 VLP production
(Nanomaterials. Vol.10, n.8 (2020), 1580, 2020-08)High Five cells are an excellent host for the production of virus-like particles (VLPs) with the baculovirus expression vector system (BEVS). However, the concurrent production of high titers of baculovirus ... -
Preparation and applications of organo-silica hybrid mesoporous silica nanoparticles for the co-delivery of drugs and nucleic acids
(Nanomaterials. Vol.10, n.12 (2020), 2466, 2020-12)Combination therapies rely on the administration of more than one drug, with independent mechanisms of action, aiming to enhance the efficiency of the treatment. For an optimal performance, the ... -
Smart dual-functionalized gold nanoclusters for spatio-temporally controlled delivery of combined chemo- and photodynamic therapy
(Nanomaterials. Vol.10, n.12 (2020), 2474, 2020-12)We report the preparation of gold nanoclusters (AuNCs) as a delivery vehicle for the clinically approved photodynamic and chemotherapeutic agents Protoporphyrin IX (PpIX) and doxorubicin (DOX), respectively, ...