Browsing IQS by Author "Bargiela, Ariadna"
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Defined D-hexapeptides bind CUG repeats and rescue phenotypes of myotonic dystrophy myotubes in a Drosophila model of the disease
Rapisarda, Anna; Bargiela, Ariadna; Llamusi, Beatriz; Pont, Isabel; Estrada Tejedor, Roger; Garcia-España, Enrique; Artero, Ruben; Perez-Alonso, Manuel (Scientific Reports, 2021-09-30)In Myotonic Dystrophy type 1 (DM1), a non-coding CTG repeats rare expansion disease; toxic double-stranded RNA hairpins sequester the RNA-binding proteins Muscleblind-like 1 and 2 (MBNL1 and 2) and ...