Browsing IQS by Author 

Browsing IQS by Author "Balcells Camps, Mercedes"

Now showing items 1-15 of 15

    • 1,2,3-Triazole Derivatives as Novel Antifibrinolytic Drugs 

      Bosch-Sanz, Oriol; Rabadà, Yvette; Biarnés Fontal, Xevi; Pedreño, Javier; Caveda, Luis; Balcells Camps, Mercedes; Martorell López, Jordi; Sánchez-García, David (International Journal of Molecular Sciences, 23(23), 2022, 14942, 2022)
      Fibrinolysis is a natural process that ensures blood fluidity through the removal of fibrin deposits. However, excessive fibrinolytic activity can lead to complications in different circumstances, such ...

    • 3D printed polymeric stent design: Mechanical testing and computational modeling 

      Canalejo Codina, Francesc; Cano Morenilla, Mariola; Martorell López, Jordi; Balcells Camps, Mercedes; Pegueroles, Marta; García Granada, Andrés-Amador (Materials & Design. 2024;247:113395, 2024-10-22)
      Polymer-based bioresorbable scaffolds (BRS) aim to reduce the long-term issues associated with metal stents. Yet, first-generation BRS designs experienced a significantly higher rate of clinical failures ...

    • A Tunable Soft Silicone Bioadhesive for Secure Anchoring of Diverse Medical Devices to Wet Biological Tissue 

      Singh, Manisha; Teodorescu, Debbie; Rowlett, Meagan; Wang, Sophie X.; Balcells Camps, Mercedes; Park, Clara; Bernardo, Bruno; McGarel, Sian; Reeves, Charlotte; Mehra, Mandeep R.; Zhao, Xuanhe; Yuk, Hyunwoo; Roche, Ellen (Advanced Materials. 2024;36(3):2307288, 2024-01-18)
      Silicone is utilized widely in medical devices for its compatibility with tissues and bodily fluids, making it a versatile material for implants and wearables. To effectively bond silicone devices to ...

    • Assessment of the angiogenic potential of 2-deoxy-D-ribose using a novel in vitro 3D dynamic model in comparison with established in vitro assays 

      Balcells Camps, Mercedes; Claeyssens, Frederik; Dikici, Serkan; Dikici, Betül Aldemir; Bhaloo, Shirin Issa; Edelman, Elazer R.; MacNeil, Sheila; Reilly, Gwendolen C.; Sherborne, Colin (Frontiers in Bioengineering and Biotechnology. Vol.7 (2020), 451, 2020-01)
      Angiogenesis is a highly ordered physiological process regulated by the interaction of endothelial cells with an extensive variety of growth factors, extracellular matrix components and mechanical ...

    • Comparing different metabolic indexes to predict type 2 diabetes mellitus in a five years follow-up cohort: The Baependi Heart Study 

      De Oliveira, Camila Maciel; Pavani, Jessica; Liu, Chunyu; Balcells Camps, Mercedes; Capasso, Robson; De Oliveira Alvim, Rafael; Mourao-Junior, Carlos Alberto; Krieger, José Eduardo; Costa Pereira, Alexandre (PLoS ONE 17(6): e0267723, 2022)
      This study evaluates the association of anthropometric indexes and the incidence of type 2 diabetes mellitus (T2DM) after a 5-year follow-up. This analysis included 1091 middle-aged participants (57% ...

    • Efficient Hydroxyapatite Extraction from Salmon Bone Waste: An Improved Lab-Scaled Physico-Chemico-Biological 

      Muñoz, Francisco; Haidar, Ziyad S.; Puigdollers, Andreu; Guerra, Ignacio; Padilla, María Cristina; Ortega, Nicole; Balcells Camps, Mercedes; García, María José (Molecules, 2024;29(17):4002, 2021-08-24)
      The demand for novel tissue grafting and regenerative wound care biomaterials is growing as traditional options often fall short in biocompatibility, functional integration with human tissue, associated ...

    • Endothelial expression of guidance cues in vessel wall homeostasis: dysregulation under proatherosclerotic conditions 

      Balcells Camps, Mercedes; Gils, Janine M. van; Ramkhelawon, Bhama; Fernandes, Luciana; Stewart, Merran C.; Guo, Liang; Seibert, Tara; Menezes, Gustavo B.; Cara, Denise C.; Chow, Camille; Kinane, T. Bernard; Fisher, Edward A.; Alvarez-Leite, Jacqueline; Lacy-Hulbert, Adam; Moore, Kathryn J. (Circulation. Vol.3, n.5 (2013), p.911–919, 2013-05)
      Background— Local modulation of vascular mammalian target of rapamycin (mTOR) signaling reduces smooth muscle cell (SMC) proliferation after endovascular interventions but may be associated with endothelial ...

    • In Vivo Efficacy of an Adhesive Bioresorbable Patch to Treat Aortic Dissections 

      Balà, Noemí; Aranda, Alejandro; Teixidó, Pau; Molhoek, Carlota; Moreno Jiménez, Inés; Febas, Germán; Lopez-Guimet, Julia; Groothuis, Adam; Edelman, Elazer; Balcells Camps, Mercedes; Borrós i Gómez, Salvador; Martorell López, Jordi; Riambau, Vicente (JACC: Basic to Translational Science. 2024;9(1):65-77, 2024-01-22)
      Endovascular repair of aortic dissection still presents significant limitations. Preserving the mechanical and biological properties set by the aortic microstructure is critical to the success of ...

    • Optimization of 3D autologous chondrocyte-seeded polyglycolic acid scaffolds to mimic human ear cartilage 

      Melgar Lesmes, Pedro; Bosch-Sanz, Oriol; Zubajlo, Rebecca; Molins, Gemma; Comfort, Sofia; Luque Saavedra, Ainara; López-Moya, Mario; García Polite, Fernando; Parri Ferrandis, Francisco José; Rogers, Carolyn; Gelabertó, Agata; Martorell López, Jordi; Edelman, Elazer R.; Balcells Camps, Mercedes (Biomaterials Science 2023, 13 (10), 2023-05)
      Auricular reconstruction in children with microtia is one of the more complex procedures in plastic surgery. Obtaining sufficient native material to build an ear requires harvesting large fragments of ...

    • Relationship between marital status and incidence of type 2 diabetes mellitus in a Brazilian rural population: the Baependi heart study 

      Balcells Camps, Mercedes; De Oliveira, Camila Maciel; Tureck, Luciane Viater; Alvares, Danilo; Liu, Chunyu; Horimoto, Andrea Roseli Vançan Russo; De Oliveira Alvim, Rafael; Krieger, José Eduardo; Costa Pereira, Alexandre (PLoS One. Vol. 15, n.8 (2020), e0236869, 2020-08)
      Many factors influence the incidence of type 2 diabetes mellitus (T2DM). Here, we investigated the associations between socio-demographic characteristics and familial history with the 5-year incidence ...

    • Smooth muscle cells orchestrate the endothelial cell response to flow and injury 

      Balcells Camps, Mercedes; Martorell López, Jordi; Olivé, Carla; Santacana, Marina; Chitalia, Vipul C.; Cardoso, Angelo A.; Edelman, Elazer R. (Circulation. Vol.121, n.20 (2010), p.2192–2199, 2010-05)
      Background—Local modulation of vascular mammalian target of rapamycin (mTOR) signaling reduces smooth muscle cell (SMC) proliferation after endovascular interventions but may be associated with endothelial ...

    • Triglyceride glucose index as a tool to motivate early lifestyle modification in young adults at diabetes risk: the baependi heart study 

      Balcells Camps, Mercedes; De Oliveira, Camila Maciel; Pavani, Jessica; Liu, Chunyu; De Oliveira Alvim, Rafael; Mourao-Junior, Carlos Alberto; Krieger, José Eduardo; Da Costa Pereira, Alexandre (Preventive medicine reports. Vol.20 (2020), 101172, 2020-12)
      Considering that the incidence of type 2 diabetes mellitus (T2DM) has been increasing especially in developing countries and becoming a global public health problem, this study aims to evaluate the ...

    • Unravelling the Antifibrinolytic Mechanism of Action of the 1,2,3-Triazole Derivatives 

      Rabadà, Yvette; Bosch-Sanz, Oriol; Biarnés Fontal, Xevi; Pedreño, Javier; Caveda, Luis; Sánchez-García, David; Martorell López, Jordi; Balcells Camps, Mercedes (International Journal of Molecular Sciences. 2024;25(13):7002, 2024-06-26)
      A new family of antifibrinolytic drugs has been recently discovered, combining a triazole moiety, an oxadiazolone, and a terminal amine. Two of the molecules of this family have shown activity that is ...

    • Uremic serum and solutes increase post-vascular interventional thrombotic risk through altered stability of smooth muscle cell tissue factor 

      Balcells Camps, Mercedes; Martorell López, Jordi; Chitalia, Vipul C.; Shivanna, Sowmya; Bosch, Irene; Kolandaivelu, Kumaran; Edelman, Elazer R. (Circulation. Vol.127, n.3 (2013), p.365–376, 2013-01)
      Background—Stent thrombosis (ST), a postinterventional complication with a mortality rate of 50%, has an incidence that rises precipitously in patients at risk. Chronic renal failure and end-stage renal ...

    • Versatile, elastomeric and degradable polyHIPEs of poly(glycerol sebacate)-methacrylate and their application in vascular graft tissue-engineering 

      Pashneh-Tala, Samand; Field, Jonathan; Fornesa, Blanca; Molins Colomer, Maite; Jackson, Caitlin E.; Balcells Camps, Mercedes; Martorell López, Jordi; Claeyssens, Frederik (Materials Today Advances 2023, 20, 100432, 2023-12)
      Polymer scaffolds are an important enabling technology in tissue engineering. A wide range of manufacturing techniques have been developed to produce these scaffolds, including porogen leaching, phase ...