Browsing IQS by Author "Universitat Ramon Llull. IQS"
Now showing items 221-240 of 257
-
Structure-function features of a mycoplasma glycolipid synthase derived from structural data integration, molecular simulations, and mutational analysis
Planas, Antoni (Planas Sauter); Biarnés Fontal, Xevi; Romero, Javier (Romero García); Francisco, Carles (PLoS One. Vol.8, n.12 (2013), e81990, 2013-12)Glycoglycerolipids are structural components of mycoplasma membranes with a fundamental role in membrane properties and stability. Their biosynthesis is mediated by glycosyltransferases (GT) that catalyze ... -
Subdiffraction localization of a nanostructured photosensitizer in bacterial cells
Agut Bonsfills, Montserrat; Nonell, Santi; Delcanale, Pietro; Pennacchietti, Francesca; Maestrini, Giulio; Rodríguez Amigo, Beatriz; Bianchini, Paolo; Diaspro, Alberto; Iagatti, Alessandro; Patrizi, Barbara; Foggi, Paolo; Abbruzzetti, Stefania; Viappiani, Cristiano (Scientific Reports. Vol.5, 15564 (2015), 2015-10)Antibacterial treatments based on photosensitized production of reactive oxygen species is a promising approach to address local microbial infections. Given the small size of bacterial cells, identification ... -
Substrate distortion in the Michaelis complex of Bacillus 1,3–1,4-β-glucanase: insight from first principles molecular dynamics simulations
Planas, Antoni (Planas Sauter); Biarnés Fontal, Xevi; Nieto, Joan; Rovira i Virgili, Carme (Journal of Biological Chemistry. Vol.281, n.3 (2006), p.1432–1441, 2006-01)The structure and dynamics of the enzyme-substrate complex of Bacillus 1,3–1,4-β-glucanase, one of the most active glycoside hydrolases, is investigated by means of Car-Parrinello molecular dynamics ... -
Sustainable development: The stock market's view of environmental policy
García Blandón, Josep; Castillo Merino, David; Chams, N. (Business Strategy and the Environment, 2020-07-08)This study applies panel data regression models to investigate how the stock market values the environmental policy of the firm. The empirical analysis relies on a cross-country sample of public firms ... -
Syndecans and Pancreatic Ductal Adenocarcinoma
Betriu Rosselló, Nausica; Bertran-Mas, Juan; Andreeva, Anna; Alonso, Anna; Semino, Carlos (Biomolecules, 2021-02-25)Pancreatic Ductal Adenocarcinoma (PDAC) is a fatal disease with poor prognosis because patients rarely express symptoms in initial stages, which prevents early detection and diagnosis. Syndecans, a ... -
Synthesis, photophysical characterization and photoinduced antibacterial activity of methylene blue-loaded amino- and mannose-targeted mesoporous silica nanoparticles
Planas Marquès, Oriol; Bresolí Obach, Roger; Nos, Jaume; Gallavardin, Thibault; Ruiz González, Rubén; Agut Bonsfills, Montserrat; Nonell, Santi (Molecules. Vol.20, n.4 (2015), p.6284-6298, 2015-04)Over the last 20 years, the number of pathogenic multi-resistant microorganisms has grown steadily, which has stimulated the search for new strategies to combat antimicrobial resistance. Antimicrobial ... -
Targeting transthyretin in Alzheimer's disease: Drug discovery of small-molecule chaperones as disease-modifying drug candidates for Alzheimer's disease
Planas, Antoni (Planas Sauter); Cotrina, Ellen Y.; Santos, Luis Miguel; Rivas, Josep; Blasi, Daniel; Leite, José Pedro; Liz, Márcia A.; Busquets, Maria Antònia; Prohens, Rafel; Gimeno, Ana; Jiménez-Barbero, Jesús; Gales, Luis; Llop, Jordi; Quintana, Jordi; Cardoso, Isabel; Arsequell, Gemma (European Journal of Medicinal Chemistry, 2021-12-15)Transthyretin (TTR) has a well-established role in neuroprotection in Alzheimer's Disease (AD). We have setup a drug discovery program of small-molecule compounds that act as chaperones enhancing ... -
Teaching Cheminformatics through a Collaborative Intercollegiate Online Chemistry Course (OLCC)
Kim, Sunghwan; Bucholtz, Ehren; Briney, Kristin; Cornell, Andrew; Cuadros, Jordi; Fulfer, Kristen; Gupta, Tanya; Hepler-Smith, Evan; Johnston, Dean; Lang, Andrew; Larsen, Delmar; Li, Ye; McEwen, Leah; Morsch, Layne; Muzyka, Jennifer; Belford, Robert (Journal of Chemical Education, 2020-12-21)While cheminformatics skills necessary for dealing with an ever-increasing amount of chemical information are considered important for students pursuing STEM careers in the age of big data, many schools ... -
Tetramethylbenzidine: an acoustogenic photoacoustic probe for reactive oxygen species detection
Nonell, Santi; Agut Bonsfills, Montserrat; Bresolí-Obach, Roger; Frattini, Marcello; Abbruzzetti, Stefania; Viappiani, Cristiano (Sensors. Vol.20, n.20 (2020), 5952, 2020-10)Photoacoustic imaging is attracting a great deal of interest owing to its distinct advantages over other imaging techniques such as fluorescence or magnetic resonance image. The availability of photoacoustic ... -
The anthropological function of dialogue in political reconciliation processes: ethical analysis of Ignacio Ellacuría's thought on the 25th anniversary of his death (1989-2014)
Sols Lucia, José (Ramon Llull Journal of Applied Ethics, Núm. 5 (2014), p.125-141, 2014)The idea of a just and lasting peace seems to be unachievable when people are suffering a civil or international war, a violent revolutionary process or a dictatorship, or when they are immersed in a ... -
The external didactic transposition of mathematics at university level: dilemmas and challenges
Bosch, Marianna; Winsløw, Carl (Educaçao Matemática Pesquisa. Vol.22, n.4 (2020) p.373-386, 2020)We develop the idea that research on university mathematics education needs to more systematically address the external didactic transposition. After outlining existing research that goes more or less ... -
The impact of the perceived risk of COVID-19 on consumers' attitude and behavior toward locally produced food
Palau i Saumell, Ramon; Matute, Jorge; Derqui, Belén; Meyer, Jan-Hinrich (British Food Journal, 2021-12-17)Purpose This study analyzes the impact of the COVID-19 pandemic on the consumption of locally produced food. In particular, it examines an extended model of the theory of planned behavior, with the ... -
The influence of the trade-off between profitability and future increases in sales on cost stickiness
García Blandón, Josep; Argilés Bosch, Josep M.; Ravenda, Diego; Valencia Silva, Maika Melina; Somoza López, Antonio (Estudios de Economía. Vol. 44, No.1 (2017), pág. 81-104, 2017-06)This study analyses cost stickiness under the dilemma between current profitability and future sales increase. When activity decreases firms are faced to keep profitability adjusting resources, while ... -
The interaction effects of firm and partner tenure on audit quality
García Blandón, Josep; Argilés Bosch, Josep M. (Accounting and Business Research. Vol.47, n.7 (2017), p.810-830, 2017-02)This paper investigates the impact of firm and partner tenure on audit quality, where audit quality is proxied by discretionary accruals. We study a sample of Spanish listed companies between 2005 and ... -
The Masking Game: Design of Activatable Antibodies and Mimetics for Selective Therapeutics and Cell Control
Lucchi, Roberta; Bentanachs, Jordi; Oller Salvia, Benjamí (ACS Central Science, 2021-04-26)The high selectivity and affinity of antibody binding havemade antibodies all-pervasive tools in therapy, diagnosis, and basic science.A plethora of chemogenetic approaches has been devised to makeantibodies ... -
The potential of proteolytic chimeras as pharmalogical tools and therapeutic agents
Coll-Martínez, Bernat; Delgado, Antonio; Crosas, Bernat (Molecules. Vol.25, n.24 (2020), 5956, 2020-12)The induction of protein degradation in a highly selective and efficient way by means of druggable molecules is known as targeted protein degradation (TPD). TPD emerged in the literature as a revolutionary ... -
The role of carbon black surface activity and specific surface area in the vulcanization reaction
Borrós i Gómez, Salvador; Tricás, N.; Vidal-Escales, E. (Afinidad. Vol.59, n.500 (2002), p.337-342, 2002)This paper reviews the work developed in studying how Carbon Black presence may affect the vulcanization process and the mechanisms by which CB and polymer interact, which has not been completely described ... -
The sequential action of MIDA9/PP2C.D1, PP2C.D2, and PP2C.D5 is necessary to form and maintain the hook after germination in the dark
Rovira, Arnau; Sentandreu, Maria; Nagatani, Akira; Leivar Rico, Pablo; Monte, Elena (Frontiers in Plant Science, 2021-03-09)During seedling etiolation after germination in the dark, seedlings have closed cotyledons and form an apical hook to protect the meristem as they break through the soil to reach the surface. Once in ... -
The Sixth Merger Wave and Wealth Effects of M&A Announcements: An Analysis of Large European Bidding Companies
Martínez Blasco, Mònica; Auguets Pratsobrerroca, Francisco Javier; García Blandón, Josep (European Accounting and Management Review, 2017-12-06)This study aims to investigate short-term market reaction, including stock returns, volatility, and trading volumes of bidder firms, around the announcement dates of relevant merger and acquisition (M&A) ... -
Therapeutic potential of N-acetylcysteine in acrylamide acute neurotoxicity in adult zebrafish
Gómez Canela, Cristian; Faria, Melissa; Prats, Eva; Hsu, Chuan-Yu; Arick, Mark A. II; Bedrossiantz, Juliette; Orozco, Manuel; Garcia-Reyero, Natàlia; Ziv, Tamar; Ben-Lulu, Shani; Admon, Arie; Gómez-Oliván, Leonardo Manuel; Raldúa, Demetrio (Scientific Reports. Vol.9, n.1 (2019), 16467, 2019-11)Two essential key events in acrylamide (ACR) acute neurotoxicity are the formation of adducts with nucleophilic sulfhydryl groups on cysteine residues of selected proteins in the synaptic terminals and ...