Visualitzant IQS per autor/a "Universitat Ramon Llull. IQS"
Ara mostrant els elements 201-220 de 257
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Role of amino terminal substitutions in the pharmacological, rewarding and psychostimulant profiles of novel synthetic cathinones
Duart-Castells, L.; Nadal Gratacós, Núria; Muralter, M.; Puster, B.; Berzosa Rodríguez, Xavier; Estrada Tejedor, Roger; Niello, M.; Bhat, S.; Pubill Sánchez, David; Camarasa, J.; Sitte, H. H.; Escubedo, E.; López-Arnau, R. (Neuropharmacology, 2021-03-15)The emergence of new synthetic cathinones continues to be a matter of public health concern. In fact, they are quickly replaced by new structurally related alternatives. The main goal of the present ... -
Role of infill parameters on the mechanical performance and weight reduction of PEI Ultem processed by FFF
Pérez Martínez, M. (Marco); Gómez Gras, Giovanni; Reyes Pozo, Guillermo; Forés-Garriga, Albert (Material & Design. Vol. 193 (2020), 108810, 2020-08)In comparison with conventional manufacturing technologies, Fused Filament Fabrication (FFF) offers countless benefits. It broadens the horizons of the design of structural components with high geometrical ... -
Role of Survivin in Bladder Cancer: Issues to Be Overcome When Designing an Efficient Dual Nano-Therapy
Arista Romero, Maria; Cascante, Anna; Fornaguera Puigvert, Cristina; Borrós i Gómez, Salvador (Pharmaceutics, 2021-11-19)Bladder cancer is the 10th most diagnosed cancer, with almost 10 M cancer deaths last year worldwide. Currently, chemotherapy is widely used as adjuvant therapy after surgical transurethral resection. ... -
Screening of ionic liquids and deep eutectic solvents for physical CO2 absorption by soft-SAFT using key performance indicators
Llovell Ferret, Félix Lluís; Alkhatib, Ismail I.I.; Ferreira, Margarida L.; Alba, Carlos G.; Bahamon, Daniel; Pereiro, Ana B.; Araújo, João M.M.; Abu-Zahra, Mohammad R.M.; Vega, Lourdes F. (Journal of Chemical and Engineering Data. Vol. 65, n.12 (2020), p.5844-5861, 2020-10)The efficient screening of solvents for CO2 capture requires a reliable and robust equation of state to characterize and compare their thermophysical behavior for the desired application. In this work, ... -
Seguimiento del aprendizaje mediante análisis de trazas en una simulación de trampas ópticas
Cuadros, Jordi; Carnicer González, Arturo; Mas Soler, Josep; Juvells Prades, Ignacio; Pedro Puente, Xavier de (Óptica Pura y Aplicada. Vol. 43, n. 2 (2010), p. 119-125, 2010)En este artículo se presenta una simulación de una trampa óptica, es decir, un haz de luz muy focalizado capaz de atrapar partículas dieléctricas alrededor de la zona focal. El programa ha sido diseñado ... -
Serotype-specific detection of dengue viruses in a nonstructural protein 1-based enzyme-linked immunosorbent assay validated with a multinational cohort
Fandos, Diana; Bosch, Irene; Reddy, Ankita; De Puig, Helena; Ludert, Juan E.; Perdomo-Celis, Federico; Narváez, Calos F.; Versiani, Alice; Nogueira, Mauricio L.; Singla, Mohit; Lodha, Rakesh; Medigeshi, Guruprasad R.; Lorenzana, Ivette; Ralde, Hugo Vicente; Gelvez-Ramirez, Margarita; Villar, Luis A.; Hiley, Megan; Mendoza, Laura; Salcedo, Nol; Herrera, Bobby Brooke; Gehrke, Lee (PLoS Neglected Tropical Diseases. Vol. 14, n.6 (2020), e0008203, 2020-06)Background Dengue virus (DENV) infections pose one of the largest global barriers to human health. The four serotypes (DENV 1–4) present different symptoms and influence immune response to subsequent ... -
Shear wave cardiovascular MR elastography using intrinsic cardiac motion for transducer-free non-invasive evaluation of myocardial shear wave velocity
Martorell López, Jordi; Polcaro, Alessandro; Troelstra, Marian Amber; Runge, Jurgen Henk; Burnhope, Emma; Guenthner, Christian; Schneider, Torben; Razavi, Reza; Ismail, Tevfik F.; Sinkus, Ralph (Scientific Reports. Vol.11, 1403 (2021), 2021-01)Changes in myocardial stiffness may represent a valuable biomarker for early tissue injury or adverse remodeling. In this study, we developed and validated a novel transducer-free magnetic resonance ... -
Shear wave cardiovascular MR elastography using intrinsic cardiac motion for transducer-free non-invasive evaluation of myocardial shear wave velocity
Troelstra, Marian Amber; Runge, Jurgen Henk; Burnhope, Emma; Polcaro, Alessandro; Guenthner, Christian; Schneider, Torben; Razavi, Reza; Ismail, Tevfik F.; Martorell López, Jordi; Sinkus, Ralph (Scientific Reports, 2021-01-14)Changes in myocardial stiffness may represent a valuable biomarker for early tissue injury or adverse remodeling. In this study, we developed and validated a novel transducer-free magnetic resonance ... -
Simple generation of human induced pluripotent stem cells using poly-β-amino esters as the non-viral gene delivery system
Borrós i Gómez, Salvador; Ramos Pérez, Víctor; Gutiérrez, Jordán; Izpisúa Belmonte, J. C.; Montserrat, Núria; Garreta, Elena; González, Federico; Eguizábal, Cristina (Journal of Biological Chemistry. Vol.286,n.14 (2011),p.12417-12428, 2011-04)Reprogramming of somatic cells to induced pluripotent stem (iPS) cells can be achieved by the delivery of a combination of transcription factors, including Oct4, Sox2, Klf4, and c-Myc. Retroviral and ... -
Simulaciones para aprender sobre el enlace, la geometría de las moléculas y la estructura de las sustancias
Cuadros, Jordi; Estrada Tejedor, Roger; Ros Blanco, Laia (Alambique. Vol.86 (2016), p.34-38, 2016)Las herramientas de modelización molecular son de uso común en investigación ypermiten explorar las estructuras de las entidades químicas y predecir las propiedades de las mismas. Del mismo modo, estos ... -
Simulación de procesos con controladores lógico-programables (PLC’s)
Barberà Moral, Eduard; García, M.; Llorca, M.; Oro, J.; Solà, D. (Afinidad. Vol.71, n.566 (2014), p.95-100, 2014-04)La realización de prácticas en el laboratorio de control de procesos presenta como mayor dificultad el coste asociado al funcionamiento del proceso, debido al consumo de reactivos, de energía o a la ... -
Simulation Approach for Hydrophobicity Replication via Injection Molding
Baldi Boleda, Tomàs; Sadeghi, Ehsan; Colominas Guàrdia, Carles; García Granada, Andrés-Amador (Polymers, 2021-06-23)Nanopattern replication of complex structures by plastic injection is a challenge that requires simulations to define the right processing parameters. Previous work managed to simulate replication for ... -
Singlet oxygen in antimicrobial photodynamic therapy: photosensitizer-dependent production and decay in E. coli
Nonell, Santi; Agut Bonsfills, Montserrat; Ragàs Amalrich, Xavier; He, Xin; Roxo-Rosa, Mónica; Rocha Gonsalves, António; Serra, Arménio C. (Molecules. Vol.18, n.3 (2013), p.2712-2725, 2013-02)Several families of photosensitizers are currently being scrutinized for antimicrobial photodynamic therapy applications. Differences in physical and photochemical properties can lead to different ... -
Síntesis y aplicación de homocompuestos de TiO2 a la eliminación de contaminantes
Colominas Guàrdia, Carles; Costa, Miquel (Afinidad. Vol.68, n.554 (2011), p.259-262, 2011-07)Existen ciertos problemas de ingeniería para la uso generalizado de reacciones fotocatalíticas. La utilización de catalizadores en forma de partículas es el mayor causante de opacidad en el medio y ... -
Smart dual-functionalized gold nanoclusters for spatio-temporally controlled delivery of combined chemo- and photodynamic therapy
Nonell, Santi; Planas, Oriol; Gallavardin, Thibault; Nieves, Ingrid; Tabero, Andrea; Villanueva, Ángeles (Nanomaterials. Vol.10, n.12 (2020), 2474, 2020-12)We report the preparation of gold nanoclusters (AuNCs) as a delivery vehicle for the clinically approved photodynamic and chemotherapeutic agents Protoporphyrin IX (PpIX) and doxorubicin (DOX), respectively, ... -
Smooth muscle cells orchestrate the endothelial cell response to flow and injury
Balcells Camps, Mercedes; Martorell López, Jordi; Olivé, Carla; Santacana, Marina; Chitalia, Vipul; Cardoso, Angelo A.; Edelman, Elazer R. (Circulation. Vol.121, n.20 (2010), p.2192–2199, 2010-05)Background—Local modulation of vascular mammalian target of rapamycin (mTOR) signaling reduces smooth muscle cell (SMC) proliferation after endovascular interventions but may be associated with endothelial ... -
Stochastic modeling reveals kinetic heterogeneity in post-replication DNA methylation
Busto-Moner, Luis; Read, Elizabeth L.; Morival, Julien; Ren, Honglei; Fahim, Arjang; Reitz, Zachary; Downing, Timothy L. (PLoS Computational Biology. Vol. 16, n.4 (2020), e1007195, 2020-04)DNA methylation is a heritable epigenetic modification that plays an essential role in mammalian development. Genomic methylation patterns are dynamically maintained, with DNA methyltransferases mediating ... -
Structural analysis of an automotive interior system: practical learning in the context of the new EHEA
Puigoriol Forcada, Josep Maria; García Granada, Andrés-Amador; Reyes Pozo, Guillermo; Peña Aguilar, Reyna Mercedes (DYNA. Vol.91 (May 2016), p.272-276, 2016-05)At the IQS School of Engineering, practices has been implemented that bring students to the industrial environment through real cases. This action is in accordance with the philosophy of the European ... -
Structural implications of the DFD-in domain in computer-aided molecular design of MAP kinase interacting kinase 2 inhibitors
Estrada Tejedor, Roger; Bou Petit, Elisabeth; Borrell Bilbao, José Ignacio; Ramón y Cajal, S. (Afinidad. Vol.74, n.578 (2017), p.83-89, 2017-04)Protein translation is a key process on cell development and proliferation that is often deregulated in cancer. MAP kinase interacting kinases 1 and 2 (Mnk1/2) play a pivotal role in regulating the ... -
Structural-functional analysis reveals a specific domain organization in family GH20 hexosaminidases
Faijes, Magda; Val Cid, Cristina; Biarnés Fontal, Xevi; Planas, Antoni (Planas Sauter) (PLoS ONE. Vol.10, n.5 (2015), e0128075, 2015-05)Hexosaminidases are involved in important biological processes catalyzing the hydrolysis of N-acetyl-hexosaminyl residues in glycosaminoglycans and glycoconjugates. The GH20 enzymes present diverse ...