Browsing IQS by Author "García-España, Enrique"
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In silico discovery of substituted pyrido[2,3-d]pyrimidines and pentamidine-like compounds with biological activity in myotonic dystrophy models
Estrada Tejedor, Roger; Borrell Bilbao, José Ignacio; Teixidó i Closa, Jordi; González, Àlex L.; Konieczn, Piotr; Llamusi, Beatriz; Delgado-Pinar, Estefanía; García-España, Enrique; Pérez-Alonso, Manuel; Artero, Rubén (PLoS ONE. Vol.12, n.6 (2017), e0178931, 2017-06)Myotonic dystrophy type 1 (DM1) is a rare multisystemic disorder associated with an expansion of CUG repeats in mutant DMPK (dystrophia myotonica protein kinase) transcripts; the main effect of these ...