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dc.contributorUniversitat Ramon Llull. IQS
dc.contributor.authorSánchez García, David
dc.contributor.authorPontón, Iris
dc.contributor.authorMartí del Rio, Andrea
dc.contributor.authorGómez Gómez, Marta
dc.date.accessioned2022-03-09T14:09:46Z
dc.date.accessioned2023-07-13T05:46:06Z
dc.date.available2022-03-09T14:09:46Z
dc.date.available2023-07-13T05:46:06Z
dc.date.issued2020-12
dc.identifier.urihttp://hdl.handle.net/20.500.14342/1122
dc.description.abstractCombination therapies rely on the administration of more than one drug, with independent mechanisms of action, aiming to enhance the efficiency of the treatment. For an optimal performance, the implementation of such therapies requires the delivery of the correct combination of drugs to a specific cellular target. In this context, the use of nanoparticles (NP) as platforms for the co-delivery of multiple drugs is considered a highly promising strategy. In particular, mesoporous silica nanoparticles (MSN) have emerged as versatile building blocks to devise complex drug delivery systems (DDS). This review describes the design, synthesis, and application of MSNs to the delivery of multiple drugs including nucleic acids for combination therapies.eng
dc.format.extent37 p.cat
dc.language.isoengcat
dc.publisherMDPIcat
dc.relation.ispartofNanomaterials. Vol.10, n.12 (2020), 2466cat
dc.rightsAttribution 4.0 International
dc.rights© L'autor/a
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceRECERCAT (Dipòsit de la Recerca de Catalunya)
dc.subject.otherNanopartículescat
dc.subject.otherMedicaments--Modes d'administraciócat
dc.subject.otherRNAcat
dc.subject.otherMesoporous silicacat
dc.subject.otherNanoparticlescat
dc.subject.otherDrug deliverycat
dc.subject.otherCo-deliverycat
dc.subject.otherCombination therapiescat
dc.titlePreparation and applications of organo-silica hybrid mesoporous silica nanoparticles for the co-delivery of drugs and nucleic acidscat
dc.typeinfo:eu-repo/semantics/articlecat
dc.typeinfo:eu-repo/semantics/publishedVersioncat
dc.rights.accessLevelinfo:eu-repo/semantics/openAccess
dc.embargo.termscapcat
dc.subject.udc539
dc.identifier.doihttps://doi.org/10.3390/nano10122466cat
dc.relation.projectIDinfo:eu-repo/grantAgreement/SUR del DEC i FSE/FI/2019 FI-B 01170cat
dc.relation.projectIDinfo:eu-repo/grantAgreement/SUR del DEC/SGR/2017-SGR-1559cat


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Attribution 4.0 International
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