Visualitzant per autor/a "Hernáez, Álvaro"
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Blood DNA methylation signature of diet quality and association with cardiometabolic traits
Domínguez-Barragán, Jorge; Fernández Sanlés, Alba; Hernáez, Álvaro; Llauradó-Pont, Joana; Marrugat, Jaume; Robinson, Oliver; Tzoulaki, Ioanna; Elosua Llanos, Roberto; Lassale, Camille (European Journal of Preventive Cardiology, 2024, 31, 191-202, 2023-10)Aims Diet quality might influence cardiometabolic health through epigenetic changes, but this has been little investigated in adults. Our aims were to identify cytosine–phosphate–guanine (CpG) dinucleotides ... -
Cancer signaling transcriptome is upregulated in type 2 diabetes mellitus
Almanza Aguilera, Enrique; Hernáez, Álvaro; Corella Piquer, Dolores; Sanllorente Melenchon, Albert, 1990-; Ros Rahola, Emilio; Portolés, Olga; Valussi, Julieta; Estruch Riba, Ramon; Coltell, Oscar; Subirana Cachinero, Isaac; Canudas i Puig, Sílvia; Razquin, Cristina; Blanchart, Gemma; Nonell, Lara; Fitó Colomer, Montserrat; Castañer, Olga (Journal of clinical medicine, 2020, vol. 10, núm. 1, 85, 2020-12-29)We aimed to explore the differences in the whole transcriptome of peripheral blood mononuclear cells between elderly individuals with and without type 2 diabetes (T2D). We conducted a microarray-based ... -
High-density lipoprotein characteristics and coronary artery disease: a Mendelian randomization study
Prats Uribe, Albert; Sayols Baixeras, Sergi; Fernández Sanlés, Alba; Subirana, Isaac; Carreras-Torres, Robert; Vilahur, Gemma; Civeira, Fernando; Marrugat, Jaume; Fitó Colomer, Montserrat; Hernáez, Álvaro; Elosua Llanos, Roberto (Metabolism Clinical and Experimental, 2020, 112: 154351, 2020-09)Background To assess whether genetically determined quantitative and qualitative HDL characteristics were independently associated with coronary artery disease (CAD). Methods We designed a two-sample ... -
Mediterranean diet decreases the initiation of use of vitamin K epoxide reductase inhibitors and their associated cardiovascular risk: a randomized controlled trial
Castro-Barquero, Sara; Ribó-Coll, Margarita; Lassale, Camille; Tresserra-Rimbau, Anna; Castañer, Olga; Pintó Sala, Xavier; Martínez-González, Miguel Ángel, 1957-; Sorlí, José V.; Salas Salvadó, Jordi; Lapetra, José; Gómez-Gracia, Enrique; Alonso Gómez, Ángel M.; Fiol Sala, Miguel; Serra Majem, Lluís; Sacanella Meseguer, Emilio; Basterra-Gortari, Francisco Javier; Portolés, Olga; Babio, Nancy; Cofán Pujol, Montserrat; Ros Rahola, Emilio; Estruch Riba, Ramon; Hernáez, Álvaro (Nutrients, 2020, no. 12: 3895, 2020-12-19)Our aim is to assess whether following a Mediterranean Diet (MedDiet) decreases the risk of initiating antithrombotic therapies and the cardiovascular risk associated with its use in older individuals ... -
Mediterranean diet maintained platelet count within a healthy range and decreased thrombocytopenia-related mortality risk: a randomized controlled trial
Hernáez, Álvaro; Lassale, Camille; Castro-Barquero, Sara; Ros Rahola, Emilio; Tresserra i Rimbau, Anna; Castañer, Olga; Pintó Sala, Xavier; Vázquez Ruiz, Zenaida; Sorlí, José V.; Salas Salvadó, Jordi; Lapetra, José; Gómez-Gracia, Enrique; Alonso Gómez, Ángel M.; Fiol, Miquel; Serra Majem, Lluís; Sacanella Meseguer, Emilio; Razquin, Cristina; Corella Piquer, Dolores; Guasch-Ferré, Marta; Cofán Pujol, Montserrat; Estruch Riba, Ramon (Nutrients, 2021, 13, 559, 2021-02)There is little information on the dietary modulation of thrombosis-related risk factors such as platelet count. We aimed to assess the effects of Mediterranean diet (MedDiet) on platelet count and ... -
Parental genetically predicted liability for coronary heart disease and risk of adverse pregnancy outcomes: a cohort study
Hernáez, Álvaro; Skåra, Karoline Hansen; Page, Christian Magnus; Mitter, Vera R.; Hernández Hernández, Marta; Magnus, Per; Njølstad, Pål R.; Andreassen, Ole A.; Corfeld, Elizabeth C.; Havdahl, Alexandra; Næss, Øyvind; Brumpton, Ben; Åsvold, Bjørn Olav; Lawlor, Deborah A.; Fraser, Abigail; Magnus, Maria Christine (BMC Medicine, 2024, 22:35, 2024-01)Background Adverse pregnancy outcomes (APO) may unmask or exacerbate a woman’s underlying risk for coronary heart disease (CHD). We estimated associations of maternal and paternal genetically predicted ... -
Role of HDL function and LDL atherogenicity on cardiovascular risk: a comprehensive examination
Hernáez, Álvaro; Soria Florido, María Trinidad; Schröder, Helmut, 1958-; Ros Rahola, Emilio; Pintó Sala, Xavier; Estruch Riba, Ramon; Salas Salvadó, Jordi; Corella Piquer, Dolores; Arós, Fernando; Serra Majem, Lluís; Martínez-González, Miguel Ángel, 1957-; Fiol Sala, Miguel; Lapetra, José; Elosua Llanos, Roberto; Lamuela Raventós, Rosa Ma.; Fitó Colomer, Montserrat (PLoS One, 2019, vol. 14, núm. 6: e0218533, 2019-06)Background High-density lipoprotein (HDL) functionality and low-density lipoprotein (LDL) atherogenic traits can describe the role of both particles on cardiovascular diseases more accurately than HDL- ...