DAU - Arxiu Digital de la URL: Envíos recientes
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The potential of proteolytic chimeras as pharmalogical tools and therapeutic agents
(Molecules. Vol.25, n.24 (2020), 5956, 2020-12)The induction of protein degradation in a highly selective and efficient way by means of druggable molecules is known as targeted protein degradation (TPD). TPD emerged in the literature as a revolutionary ... -
Role of infill parameters on the mechanical performance and weight reduction of PEI Ultem processed by FFF
(Material & Design. Vol. 193 (2020), 108810, 2020-08)In comparison with conventional manufacturing technologies, Fused Filament Fabrication (FFF) offers countless benefits. It broadens the horizons of the design of structural components with high geometrical ... -
Preparative scale production of recombinant human transthyretin for biophysical studies of protein-ligand and protein-protein interactions
(International Journal of Molecular Sciences. Vol.21, n.24 (2020), 9640, 2020-12)Human transthyretin (hTTR), a serum protein with a main role in transporting thyroid hormones and retinol through binding to the retinol-binding protein, is an amyloidogenic protein involved in familial ... -
Zwitterionic 3D-printed non-immunogenic stealth microrobots
(Advanced Materials. Vol.32, n.42 (2020), 2003013, 2020-08)Microrobots offer transformative solutions for non-invasive medical interventions due to their small size and untethered operation inside the human body. However, they must face the immune system as a ... -
Screening of ionic liquids and deep eutectic solvents for physical CO2 absorption by soft-SAFT using key performance indicators
(Journal of Chemical and Engineering Data. Vol. 65, n.12 (2020), p.5844-5861, 2020-10)The efficient screening of solvents for CO2 capture requires a reliable and robust equation of state to characterize and compare their thermophysical behavior for the desired application. In this work, ... -
Relationship between marital status and incidence of type 2 diabetes mellitus in a Brazilian rural population: the Baependi heart study
(PLoS One. Vol. 15, n.8 (2020), e0236869, 2020-08)Many factors influence the incidence of type 2 diabetes mellitus (T2DM). Here, we investigated the associations between socio-demographic characteristics and familial history with the 5-year incidence ... -
Measuring Psychosocial Reactions to COVID-19: The COVID Reaction Scales (COVID-RS) as a New Assessment Tool
(Frontiers in Psychology, 2020, Vol. 11, Article 607064, 2020)Knowing and measuring the psychosocial reactions of people to the coronavirus crisis could be useful for predicting citizen responsibility and psychological well-being in the general population. In this ... -
Stochastic modeling reveals kinetic heterogeneity in post-replication DNA methylation
(PLoS Computational Biology. Vol. 16, n.4 (2020), e1007195, 2020-04)DNA methylation is a heritable epigenetic modification that plays an essential role in mammalian development. Genomic methylation patterns are dynamically maintained, with DNA methyltransferases mediating ... -
Triglyceride glucose index as a tool to motivate early lifestyle modification in young adults at diabetes risk: the baependi heart study
(Preventive medicine reports. Vol.20 (2020), 101172, 2020-12)Considering that the incidence of type 2 diabetes mellitus (T2DM) has been increasing especially in developing countries and becoming a global public health problem, this study aims to evaluate the ... -
Detección de déficits neuromusculares a través del análisis del patrón de salto y aterrizaje en deportistas adolescentes
(Cuadernos de Psicología del Deporte, Vol. 21, Núm. 3, 224-232, 2021)El objetivo principal del presente estudio fue analizar el rendimiento de la técnica del salto y aterrizaje en deportistas adolescentes mediante la versión modificada del Tuck ... -
Do folate-receptor targeted liposomal photosensitizers enhance photodynamic therapy selectivity?
(Biochimica et Biophysica Acta (BBA) -Biomembranes. Vol.1808, n.4 (2011), p.1063-1071, 2011-01)One of the current goals in photodynamic therapy research is to enhance the selective targeting of tumor cells in order to minimize the risk and the extension of unwanted side-effects caused by normal ... -
Conjugated polymers: synthesis and applications in optoelectronics
(Afinidad. Vol.71, n.568 (2014), p.251-262, 2014-10)In the last 50 years the development of conjugated polymers for applications in optoelectronics and energy has attracted great interest because of its use as conductive polymers, in solar cells or ... -
Análisis del uso de estrategias complejas de personas con discapacidad intelectual en un contexto de visoconstrucción
(Revista Española de Discapacidad, 2021, Vol. 9, Núm. 2, 135-152, 2021)El objetivo del estudio fue valorar la capacidad de planificación , en un contexto de visoconstrucción, de un grupo de personas con discapacidad intelectual. Los 70 participantes eran ... -
Tetramethylbenzidine: an acoustogenic photoacoustic probe for reactive oxygen species detection
(Sensors. Vol.20, n.20 (2020), 5952, 2020-10)Photoacoustic imaging is attracting a great deal of interest owing to its distinct advantages over other imaging techniques such as fluorescence or magnetic resonance image. The availability of photoacoustic ... -
Quintuple helix and innovation on performance of SMEs within ability of SMEs as a mediator variable: a comparative study of creative industry in Indonesia and Spain
(Management Science Letters. Vol. 10, n.6 (2020), p.1389-1400, 2020)The purpose of this study is to analyse the effects of (1) quintuple helix on small and medium enterprises (SMEs) performance; (2) ability of SMEs on SMEs performance; (3) quintuple helix on ability of ... -
Smart dual-functionalized gold nanoclusters for spatio-temporally controlled delivery of combined chemo- and photodynamic therapy
(Nanomaterials. Vol.10, n.12 (2020), 2474, 2020-12)We report the preparation of gold nanoclusters (AuNCs) as a delivery vehicle for the clinically approved photodynamic and chemotherapeutic agents Protoporphyrin IX (PpIX) and doxorubicin (DOX), respectively, ... -
New developments in vertebroplasty materials
(Afinidad. Vol.75, n.583 (2018), p.165-174, 2018-07)Increasing life expectancy is leading to an increase in age-related diseases, like osteoporosis, which often involve the breakdown of bone. One of the main problems related with such disease is the ... -
Cancer signaling transcriptome is upregulated in type 2 diabetes mellitus
(Journal of clinical medicine, 2020, vol. 10, núm. 1, 85, 2020-12-29)We aimed to explore the differences in the whole transcriptome of peripheral blood mononuclear cells between elderly individuals with and without type 2 diabetes (T2D). We conducted a microarray-based ... -
Intellectual disability, exercise and aging: the IDEA study: study protocol for a randomized controlled trial
(BMC Public Health, 2020, 20, 1266, 2020-08-20)Background People with intellectual disabilities (ID) have low levels of physical activity (PA) together with accelerated aging profiles. Adherence to PA interventions for persons with ID is low based ... -
Behavioural Improvements in Children with Autism Spectrum Disorder after Participation in an Adapted Judo Programme Followed by Deleterious Effects during the COVID-19 Lockdown
(International Journal of Environmental Research and Public Health, 2021, 18, 8015, 2021)The public health lockdown prompted by the novel coronavirus (COVID-19) pandemic, which included school closures that may have potentially serious consequences for people with disabilities or special ...