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Mostrando ítems 121-140 de 4131

    • Enzymatic Hydrolysis of Human Milk Oligosaccharides. The Molecular Mechanism of Bifidobacterium Bifidum Lacto-N-biosidase 

      Cuxart, Irene; Coines, Joan; Esquivias, Oriol; Faijes, Magda; Planas, Antoni (Planas Sauter); Biarnés Fontal, Xevi; Rovira, Carme (ACS Catalysis 2022, 12(8), 4737–4743, 2022)
      Bifidobacterium bifidum lacto-N-biosidase (LnbB) is a critical enzyme for the degradation of human milk oligosaccharides in the gut microbiota of breast-fed infants. Guided by recent crystal structures, ...

    • Environmental levels of carbaryl impair zebrafish larvae behaviour: The potential role of ADRA2B and HTR2B 

      Faria, Melissa; Bellot, Marina; Bedrossiantz, Juliette; Rosas Ramírez, Jonathan Ricardo; Prats, Eva; Garcia-Reyero, Natàlia; Gómez Canela, Cristian; Mestres, Jordi; Rovira, Xavier; Barata, Carlos; Gómez-Oliván, Leobardo Manuel; Llebaria, Amadeu; Raldúa, Demetrio (Journal of Hazardous Materials Volume 2022, 431,128563, 2022)
      The insecticide carbaryl is commonly found in indirectly exposed freshwater ecosystems at low concentrations considered safe for fish communities. In this study, we showed that after only 24 h of exposure ...

    • Dual-Functionalized Nanoliposomes Achieve a Synergistic Chemo-Phototherapeutic Effect 

      Lazaro Carrillo, Ana; Rodríguez Amigo, Beatriz; Mora, Margarita; Sagristá, M. Lluïsa; Cañete, Magdalena; Nonell, Santi; Villanueva, Ángeles (International Journal of Molecular Sciences, 23(21), 2022, 12817, 2022)
      The enhancement of photodynamic therapy (PDT) effectiveness by combining it with other treatment modalities and improved drug delivery has become an interesting field in cancer research. We have prepared ...

    • Blockchain, NFT y producción bajo demanda en el sector de la moda 

      Martín-Guart, Ramon Francisco; Fondevila-Gascón, Joan-Francesc; Lladós, Josep; Paitiví, Imma (Questiones publicitarias, vol. 7, núm. 34, 2024, 2024)
      El objeto de estudio consiste en investigar la disposición de los consumidores hacia productos bajo demanda y tokens no fungibles (NFTs), centrándose en la marca Laagam, e-commerce especializado en moda, ...

    • Més enllà del nou cinema rural 

      Colell, Judith (Qüestions de vida cristiana, núm. 275, 2023, 2023)

    • Comparing different metabolic indexes to predict type 2 diabetes mellitus in a five years follow-up cohort: The Baependi Heart Study 

      De Oliveira, Camila Maciel; Pavani, Jessica; Liu, Chunyu; Balcells Camps, Mercedes; Capasso, Robson; De Oliveira Alvim, Rafael; Mourao-Junior, Carlos Alberto; Krieger, José Eduardo; Costa Pereira, Alexandre (PLoS ONE 17(6): e0267723, 2022)
      This study evaluates the association of anthropometric indexes and the incidence of type 2 diabetes mellitus (T2DM) after a 5-year follow-up. This analysis included 1091 middle-aged participants (57% ...

    • Characterization of a Glycolipid Synthase Producing α-Galactosylceramide in Bacteroides fragilis 

      Caballé, Marc; Faijes, Magda; Planas, Antoni (Planas Sauter) (International Journal of Molecular Sciences 2022, 23(22), 13975, 2022)
      Glycolipids are complex molecules involved in important cellular processes. Among them, the glycosphingolipid α-galactosylceramide has proven to be of interest in biomedicine for its immunostimulatory ...

    • Complex pBAE Nanoparticle Cell Trafficking: Tracking Both Position and Composition Using Super Resolution Microscopy 

      Riera, Roger; Tauler, Jana; Feiner Gracia, Natàlia; Borrós i Gómez, Salvador; Fornaguera Puigvert, Cristina; Albertazzi, Lorenzo (ChemMedChem 2022, 17(13), e202100633, 2022)
      Nanomedicine emerged some decades ago with the hope to be the solution for most unmet medical needs. However, tracking materials at nanoscale is challenging to their reduced size, below the resolution ...

    • Cost behavior in e-commerce firms 

      Argilés Bosch, Josep M.; García Blandón, Josep; Ravenda, Diego (Electronic Commerce Research 2022, 23, 2101-2134, 2022)
      We conduct empirical research on the flexibility of operating costs of e-commerce firms. With an international sample of firms from different European countries, we find that e-commerce firms have a ...

    • Current progress in bionanomaterials to modulate the epigenome 

      Rhodes, Anna D. Y.; Duran Mota, José Antonio; Oliva, Núria (Biomaterials Science 2022, 18, 5021-5358, 2022)
      Recent advances in genomics during the 1990s have made it possible to study and identify genetic and epigenetic responses of cells and tissues to various drugs and environmental factors. This has ...

    • Deconstructing Markush: Improving the R&D Efficiency Using Library Selection in Early Drug Discovery 

      Manen Freixa, Leticia; Borrell Bilbao, José Ignacio; Teixidó i Closa, Jordi; Estrada Tejedor, Roger (Pharmaceuticals 2022, 15(9), 1159, 2022)
      Most of the product patents claim a large number of compounds based on a Markush structure. However, the identification and optimization of new principal active ingredients is frequently driven by a ...

    • Reivindicar els drets humans en un món convuls 

      Mateos, Oscar (Qüestions de vida cristiana, núm. 277, 2023, 2023)

    • Bioprocess Strategies for Vitamin B12 Production by Microbial Fermentation and Its Market Applications 

      Calvillo, Alvaro; Pellicer Moya, Maria Teresa; Carnicer, Marc; Planas, Antoni (Planas Sauter) (Bioengineering 2022, 9(8), 365, 2022)
      Vitamin B12 is a widely used compound in the feed and food, healthcare and medical industries that can only be produced by fermentation because of the complexity of its chemical synthesis. For this ...

    • Increased consumption of virgin olive oil, nuts, legumes, whole grains, and fish promotes HDL functions in humans 

      Hernáez, Álvaro; Sanllorente Melenchon, Albert; Castañer, Olga; Martínez-González, Miguel Ángel; Ros, Emilio; Pintó Sala, Xavier; Estruch Riba, Ramon; Salas Salvadó, Jordi; Corella Piquer, Dolores; Alonso Gómez, Ángel M.; Serra Majem, Lluís; Fiol, Miquel; Lapetra, José; Gómez-Gracia, Enrique; de la Torre, Rafael; Lamuela Raventós, Rosa Ma.; Fitó Colomer, Montserrat (Molecular nutrition and food research, 2019, 63(6): 1800847, 2019-01)
      Scope To evaluate whether increases in the consumption of cardioprotective food groups (virgin olive oil, nuts, fruits/vegetables, legumes, whole grains, fish, and wine) are associated with improvements ...

    • A hybrid numerical-experimental strategy for predicting mechanical response of components manufactured via FFF 

      Dialami, Narges; Chiumenti, Michele; Cervera, Miguel; Chasco, Uxue; Reyes Pozo, Guillermo; Pérez Martínez, M. (Marco) (Composite Structures 298 (2022) 115998, 2022)
      In this paper a new methodology developed for predicting the mechanical performance of the structures additively manufactured by Fused Filament Fabrication is presented. The novelty of the approach ...

    • A Double Payload Complex between Hypericin and All-trans Retinoic Acid in the β-Lactoglobulin Protein 

      Rodríguez Amigo, Beatriz; Hally, Cormac; Roig Yanovsky, Núria; Delcanale, Pietro; Abbruzzetti, Stefania; Agut Bonsfills, Montserrat; Viappiani, Cristiano; Nonell, Santi (Antibiotics, 11(2), 2022, 282, 2022)
      Combined therapies are usually used to treat acne vulgaris since this approach can tackle various foci simultaneously. Using a combination of spectroscopic, computational, and microbiological techniques ...

    • A computational drop-in assessment of hydrofluoroethers in Organic Rankine Cycles 

      Jovell, Daniel; González Olmos, Rafael; Llovell Ferret, Félix Lluís (Energy, 254 Part B (2022), 124319, 2022)
      Organic Rankine Cycles (ORCs) are experiencing a growing interest due to their ability to generate electricity from residual low waste heat sources. HFC-245fa is a representative working fluid for ORC ...

    • 1H-Pyrazolo[3,4-b]pyridines: Synthesis and Biomedical Applications 

      Donaire-Arias, Ana; Montagut, Ana Maria; Puig de la Bellacasa Cazorla, Raimon; Teixidó i Closa, Jordi; Borrell Bilbao, José Ignacio (Molecules 27(7), 2022, 2237, 2022)
      Pyrazolo[3,4-b]pyridines are a group of heterocyclic compounds presenting two possible tautomeric forms: the 1H- and 2H-isomers. More than 300,000 1H-pyrazolo[3,4-b]pyridines have been described which ...

    • 1,2,3-Triazole Derivatives as Novel Antifibrinolytic Drugs 

      Bosch-Sanz, Oriol; Rabadà, Yvette; Biarnés Fontal, Xevi; Pedreño, Javier; Caveda, Luis; Balcells Camps, Mercedes; Martorell López, Jordi; Sánchez García, David (International Journal of Molecular Sciences, 23(23), 2022, 14942, 2022)
      Fibrinolysis is a natural process that ensures blood fluidity through the removal of fibrin deposits. However, excessive fibrinolytic activity can lead to complications in different circumstances, such ...

    • Automotive Electrification Challenges Shown by Real-World Driving Data and Lifecycle Assessment 

      Neidhardt, Michael; Mas-Peiro, Jordi; Schneck, Antonia; Pou Ibar, Josep Oriol, 1980-; González Olmos, Rafael; Kwade, Arno; Schmuelling, Benedikt (Sustainability 2022, 14(23), 15972, 2022)
      Electric mobility is considered a solution to reduce carbon emissions. We expanded a lifecycle assessment with data on technical limitations and driving habits (based on real-world data) in order to ...