Recerca: Enviaments recents
Ara mostrant els elements 121-140 de 4018
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Nanocarriers for Combination Therapy in Pancreatic Ductal Adenocarcinoma: A Comprehensive Review
(Nanomaterials 2025, 15 (15), 1139, 2025-08-01)Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest cancers worldwide, characterized by late diagnosis, aggressive progression, and poor response to conventional monotherapies. Combination ... -
Revolutionizing rheumatoid arthritis therapy: the potential of lipid nanocarriers
(RSC Advances, 2025,15 (33), 27388-27402, 2025-08)Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by synovitis, systemic inflammation and autoantibodies, leading to joint damage and disability. RA pathogenesis is characterized ... -
Go for Gold: Development of a Scalable Synthesis of [1-(Ethoxycarbonyl)cyclopropyl] Triphenylphosphonium Tetrafluoroborate, a Key Reagent to Explore Covalent Monopolar Spindle 1 Inhibitors
(ChemistryOpen 2025, 14 (9), 2025-09)Covalent approaches have resurged in drug discovery and chemical biology during the last decade. So-called targeted covalent inhibitors typically show a strong and persistent drug–target interaction as ... -
The Influence of Gender Discrimination and Gender Equality on Corporate Tax Aggressiveness
(Corporate Social Responsibility and Environmental Management 2025, 32 (5), 5956-5977, 2025-09)In this paper, we examine whether gender diversity on board audit committees promotes socially responsible corporate tax behavior by analyzing the influence of female directors on aggressive tax strategies. ... -
miRNAs and exosomes in psoriasis: coordinating cytoskeleton dynamics and extracellular matrix remodeling
(Frontiers in Cell and Developmental Biology 2025, 13, 2025-07)Psoriasis is a chronic inflammatory skin disorder characterized by hyperproliferation of keratinocytes, immune dysregulation, and abnormal epidermal differentiation. Its pathogenesis involves complex ... -
Development of simplified poly(β-aminoester)-zwitterion nanovehicles for transfection of cancer cells and improved gene delivery across a cell-based model of the blood-brain barrier
(Drug delivery and translational research 2025, 2025-07)Although nucleotide-based therapeutics hold promise for a variety of diseases, their clinical application is limited because of low stability and poor bioavailability. Among non-viral gene delivery ... -
Polar π stacking for metal-free near, remote, and ultra-remote C–H coupling with aryliodanes
(Chem 2025, 11 (6), 2025-06)We introduce a C–H coupling process in which an aromatic C–I position serves as trampoline for targeting various aromatic C–H positions. The reaction is set in motion by an interaction between the ... -
A geometric and morphometric methodology for evaluating low-cost 3D facial acquisition and reconstruction techniques
(Lecture Notes in Computer Science, Vol. 14062, pp. 603-614, 2025-06-25)Recent studies in neuropsychiatry have highlighted the correlation between facial and brain dysmorphologies. One way of simultaneously analysing the brain and the face of a subject is by reconstructing ... -
Automated orientation detection of 3D head reconstructions from sMRI using multiview orthographic projections: An image classification-based approach
(Lecture Notes in Computer Science, Vol. 14062, pp. 603-614, 2023-06)Recent studies in neuropsychiatry have highlighted the correlation between facial and brain dysmorphologies. One way of simultaneously analysing the brain and the face of a subject is by reconstructing ... -
Geomagnetically induced currents in a power grid of northeastern Spain
(Space Weather, 10, S06002, 2012-06-07)Using the geomagnetic records of Ebro geomagnetic observatory and taking the plane wave assumption for the external current source and a homogeneous Earth conductivity, a prediction of the effects of ... -
Quantifying the Performance of Geomagnetically Induced Current Models
(Space Weather, 17, 941–949, 2019-07-24)We describe a metric that has been repeatedly applied to assess the performance of models aimed at predicting geomagnetically induced currents from Space Weather events. The used parameterization, ... -
Understanding the Toxicity of Metal-Based Nanomaterials: Current Insights, Challenges, and Future Directions
(ACS Materials Letters 2025, 7 (7), 2025-07-07)This review provides an overview of the current knowledge regarding the nanotoxicological impact of metal-based nanomaterials intended for biomedical applications. The extensive application of nanotechnology ... -
Analysing the Effects of Organisational Politics on Nurses' Outcomes: The Moderating Role of Nurses' Professional Self-Concept
(The Journal of Advanced Nursing 2025, 81 (8), 4351-5223, 2025-05)Aims: To analyse how organisational politics can affect behavioural responses such as organisational deviance and organisational citizenship behaviour towards the organisation among nurses. It also ... -
A critical comparison between template-based and architecture-reused deep learning methods for generic 3D landmarking of anatomical structures
(Lecture Notes in Computer Science, Vol. 1527, pp 97-111., 2024-10-26)Shape alterations in body organs are common pathological hallmarks of multiple disorders, making quantitative shape analysis key for obtaining diagnostic and prognostic biomarkers. In this context, ... -
Full-range yaw prediction: A multi-view approach for 3D head model pose estimation using convolutional neural network
(Proceedings of the 25th International Conference of the Catalan Association for Artificial Intelligence, 2023)Head pose estimation, a crucial task in computer vision, involves determining the orientation of a person’s head in 3D space through yaw, pitch, and roll angles. While recent techniques present excellent ... -
Landmark anything: Multi-view consensus convolutional networks applied to the 3D landmarking of anatomical structures
(Proceedings of the 26th International Conference of the Catalan Association for Artificial Intelligence, 2024)As shape alterations in three-dimensional biological structures are associated to numerous pathological processes, quantitative shape analysis for obtaining phenotypic biomarkers of diagnostic potential ... -
Ruthenium(II) Polypyridyl Complexes Containing COUBPY Ligands as Potent Photosensitizers for the Efficient Phototherapy of Hypoxic Tumors
(Journal of the American Chemical Society 2025, 147 (9), 7360–7376, 2025-03-05)Hypoxia, a hallmark of many solid tumors, is linked to increased cancer aggressiveness, metastasis, and resistance to conventional therapies, leading to poor patient outcomes. This challenges the ... -
DEArt: Building and evaluating a dataset for object detection and pose classification for European art
(Journal of Cultural Heritage 2025, 75, 2025-10)Annotation of cultural heritage artefacts allows finding and exploration of items relevant to user needs, supports functionality such as question answering or scene understanding, and in general facilitates ... -
Electrostatic potential as a reactivity scoring function in computer-assisted enzyme engineering
(The FEBS Journal 2025, 292 (16), 4211-4231, 2025-08)The high catalytic efficiency of enzymes is attained, in part, by their capacity to stabilize electrostatically the transition state of the chemical reaction. High-throughput protocols for measuring ... -
Eco-Friendly Mechanochemical Fabrication of Polypyrrole/Ag-ZnO Heterostructures for Enhanced Photocatalytic Degradation of Methyl Orange
(Catalysts 2025, 15 (3), 2025-03)A Ppy/Ag-ZnO catalyst was successfully synthesized at room temperature using a novel, green methodology. It involves a mechanically assisted metathesis reaction. The Ppy/Ag-ZnO catalyst was analyzed via ...