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Different mechanisms that promote protein monoubiquitination
(Afinidad. Vol.72, n.570 (2015), p.95-100, 2015-04)Protein monoubiquitination is a post-translational modification that consists of the conjugation of a single ubiquitin molecule to a target protein residue. Monoubiquitination regulates protein activity ... -
The potential of proteolytic chimeras as pharmalogical tools and therapeutic agents
(Molecules. Vol.25, n.24 (2020), 5956, 2020-12)The induction of protein degradation in a highly selective and efficient way by means of druggable molecules is known as targeted protein degradation (TPD). TPD emerged in the literature as a revolutionary ...