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Simple generation of human induced pluripotent stem cells using poly-β-amino esters as the non-viral gene delivery system
Borrós i Gómez, Salvador; Ramos Pérez, Víctor; Gutiérrez, Jordán; Izpisúa Belmonte, J. C.; Montserrat, Núria; Garreta, Elena; González, Federico; Eguizábal, Cristina (Journal of Biological Chemistry. Vol.286,n.14 (2011),p.12417-12428, 2011-04)Reprogramming of somatic cells to induced pluripotent stem (iPS) cells can be achieved by the delivery of a combination of transcription factors, including Oct4, Sox2, Klf4, and c-Myc. Retroviral and ...