Browsing by Subject "Singlet oxygen"
Now showing items 1-13 of 13
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A comparative study on two cationic porphycenes: photophysical and antimicrobial photoinactivation evaluation
(International Journal of Molecular Sciences. Vol.16, n.11 (2015), p.27072-27086, 2015-11)Over the last decades, the number of pathogenic multi-resistant microorganisms has grown dramatically, which has stimulated the search for novel strategies to combat antimicrobial resistance. Antimicrobial ... -
An antibody-photosensitiser bioconjugate overcomes trastuzumab resistance in HER2-positive breast cancer
(European Journal of Medicinal Chemistry 2025, 290, 2025-06-05)HER2-positive breast cancer, characterized by the overexpression of HER2 receptors, often develops resistance to trastuzumab, limiting its therapeutic efficacy. In this study, we explore the use of ... -
Antimicrobial efficacy of solar disinfection in cellulose fiber supported photoactive materials
(Materials Today Communications. 2024;38:107858, 2023-12-29)According to the World Health Organization, antimicrobial resistance is one of the emerging threats to global health. Therefore, the development of new strategies to mitigate resistant bacterial strains ... -
Cluster and Kill: the Use of Clustering-Triggered Emission Materials for Singlet Oxygen Photosensitization in Antimicrobial Photodynamic Therapy
(Advanced Optical Materials 2025, 13 (3), 2402179, 2025-01-24)The emergence of light-based technologies is revolutionizing modern medicine and healthcare by enabling precise disease diagnosis and treatment through various luminescent agents and imaging techniques. ... -
Do folate-receptor targeted liposomal photosensitizers enhance photodynamic therapy selectivity?
(Biochimica et Biophysica Acta (BBA) -Biomembranes. Vol.1808, n.4 (2011), p.1063-1071, 2011-01)One of the current goals in photodynamic therapy research is to enhance the selective targeting of tumor cells in order to minimize the risk and the extension of unwanted side-effects caused by normal ... -
NanoFN10: A High-Contrast Turn-On Fluorescence Nanoprobe for Multiphoton Singlet Oxygen Imaging
(Sensors 2023, 23(10), 4603, 2023-05)An “off-on” fluorescent nanoprobe for near-infrared multiphoton imaging of singlet oxygen has been developed. The nanoprobe comprises a naphthoxazole fluorescent unit and a singlet-oxygen-sensitive furan ... -
Photosensitive EGFR-Targeted Nanocarriers for Combined Photodynamic and Local Chemotherapy
(Pharmaceutics 2022, 14(2), 405, 2022-02)The major limitation of any cancer therapy lies in the difficulty of precisely controlling the localization of the drug in the tumor cells. To improve this drawback, our study explores the use of ... -
Photosensitizing proteins for antibacterial photodynamic inactivation
(Translational Biophotonics. Vol.2, n.1-2 (2020) e201900031, 2020-05)We review recent applications of water‐soluble proteins as carriers for photosensitizing molecules in antimicrobial photodynamic therapy (aPDT). The low water solubility of photosensitizers and their ... -
Riboflavin-binding proteins for singlet oxygen production
(Photochemical & Photobiological Sciences 2022, 21, 1545–1555, 2022)miniSOG, developed as the first fully genetically encoded singlet oxygen photosensitiser, has found various applications in cell imaging and functional studies. Yet, miniSOG has suboptimal properties, ... -
Singlet oxygen in antimicrobial photodynamic therapy: photosensitizer-dependent production and decay in E. coli
(Molecules. Vol.18, n.3 (2013), p.2712-2725, 2013-02)Several families of photosensitizers are currently being scrutinized for antimicrobial photodynamic therapy applications. Differences in physical and photochemical properties can lead to different ... -
Synthesis, photophysical characterization and photoinduced antibacterial activity of methylene blue-loaded amino- and mannose-targeted mesoporous silica nanoparticles
(Molecules. Vol.20, n.4 (2015), p.6284-6298, 2015-04)Over the last 20 years, the number of pathogenic multi-resistant microorganisms has grown steadily, which has stimulated the search for new strategies to combat antimicrobial resistance. Antimicrobial ... -
Tetramethylbenzidine: an acoustogenic photoacoustic probe for reactive oxygen species detection
(Sensors. Vol.20, n.20 (2020), 5952, 2020-10)Photoacoustic imaging is attracting a great deal of interest owing to its distinct advantages over other imaging techniques such as fluorescence or magnetic resonance image. The availability of photoacoustic ... -
Una visión moderna sobre la desactivación de cetonas aromáticas por beta-fenilos
(Afinidad. Vol.73, n.574 (2016), p.90-95, 2016-04)La desactivación por beta fenilos (en inglés, Beta Phenyl Quenching o BPQ) es una reacción que se produce a partir del estado triplete de cetonas aromáticas con un grupo fenilo en posición beta. Esta ...