Browsing by Subject "Nanomedicina"
Now showing items 1-5 of 5
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A novel fluoro-chromogenic click reaction for the labelling of proteins and nanoparticles with near-IR theranostic agents
(Chemical Communications. Vol.51, n.26 (2015), p.5586-5589, 2014-12)Reaction of porphycene isothiocyanates with primary and secondary amines leads to the formation of thiazolo[4,5-c]porphycenes, with a substantial shift in the absorption and fluorescence spectra. The ... -
Dual stimuli-responsive polyphosphazene-based molecular gates for controlled drug delivery in lung cancer cells
(RSC Advances. Vol.10, n.46 (2020), p.27305-27314, 2020-07)A switchable silane derived stimuli-responsive bottle-brush polyphosphazene (PPz) was prepared and attached to the surface of mesoporous silica nanoparticles (MSNs). The hybrid polymer with PEG-like ... -
Effect of surface functionalization and loading on the mechanical properties of soft polymeric nanoparticles prepared by nano-emulsion templating
(Colloids and Surfaces B: Biointerfaces 2023, 222, 113019, 2023-02)Drug and gene delivery systems based on polymeric nanoparticles offer a greater efficacy and a reduced toxicity compared to traditional formulations. Recent studies have evidenced that their internalization, ... -
Fine-tuning formulation and biological interaction of doxorubicin-loaded polymeric nanoparticles via electrolyte concentration modulation
(Journal of Molecular Liquids, 2023, vol. 390, part A, 122986, 2023-09)Doxorubicin (DOX) is amongst the most widely used chemotherapeutic drugs against various cancers. However, its controlled biodistribution to the tumor site at the required pharmacokinetics profile ... -
Nanomedicine in non-small cell lung cancer: from conventional treatments to immunotherapy
(Cancers. Vol.12, n.6 (2020), 1609, 2020-06)Non-small cell lung cancer (NSCLC) remains the most common cause of cancer-related mortality. The heterogeneous nature of this disease hinders its diagnosis and treatment, requiring continuous advances ...