Visualitzant per matèria "Behavior"
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A Zebrafish Model of Neurotoxicity by Binge-Like Methamphetamine Exposure
(Frontiers in Pharmacology, 2021-11-22)Hyperthermia is a common confounding factor for assessing the neurotoxic effects of methamphetamine (METH) in mammalian models. The development of new models of methamphetamine neurotoxicity using ... -
Aqueous stability and degradation of psychiatric and neuroactive compounds and its biological activity in Daphnia magna
(Science of the Total Environment, 2021-07-28)Pharmaceuticals and other emerging contaminants are continuously released into the aquatic environment, considered as ‘pseudo-persistent’ pollutants. Many compounds degrade fast in the environment, but ... -
Cardiac and neurobehavioral impairments in three phylogenetically distant aquatic model organisms exposed to environmentally relevant concentrations of boscalid
(Environmental Pollution. 2024;347:123685, 2024-03-16)Boscalid (2-Chloro-N-(4′-chlorobiphenyl-2-yl) nicotinamide), a pyridine carboxamide fungicide, is an inhibitor of the complex II of the respiration chain in fungal mitochondria. As boscalid is only ... -
Daphnia magna an emerging environmental model of neuro and cardiotoxicity of illicit drugs
(Environmental Pollution, 2024-02-14)Cocaine, methamphetamine, ectasy (3,4-methylenedioxy amphetamine (MDMA)) and ketamine are among the most consumed drugs worldwide causing cognitive, oxidative stress and cardiovascular problems in humans. ... -
Environmental levels of carbaryl impair zebrafish larvae behaviour: The potential role of ADRA2B and HTR2B
(Journal of Hazardous Materials Volume 2022, 431,128563, 2022)The insecticide carbaryl is commonly found in indirectly exposed freshwater ecosystems at low concentrations considered safe for fish communities. In this study, we showed that after only 24 h of exposure ... -
Phototactic behaviour and neurotransmitter profiles in two Daphnia magna clones: Vertical and horizontal responses to fish kairomones and psychotropic drugs
(Science of The Total Environment, 2022-03-18)Animal behavioural responses are increasingly being used in environmental risk assessment. Nevertheless, behavioural responses are still hampered by a lack of standardisation. Phototactic behaviour in ... -
Short-term exposure to environmental levels of nicotine and cotinine impairs visual motor response in zebrafish larvae through a similar mode of action: Exploring the potential role of zebrafish α7 nAChR
(Science of the Total Environment, 2023-12-14)The current view is that environmental levels of nicotine and cotinine, commonly in the ng/L range, are safe for aquatic organisms. In this study, 7 days post-fertilization zebrafish embryos have been ... -
The role of serotonergic signaling on phototactic and locomotor behavior in Daphnia magna
(Science of The Total Environment 2023, 856 (Part 2), 159042, 2023-01-15)The role of serotonin in Daphnia magna phototactic and locomotor behavior was assessed using reverse genetics and pharmacological treatments with serotonin and fluoxetine. The study was conducted with ...