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Visualitzant per matèria "Fotoquimioteràpia"

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    • A comparative study on two cationic porphycenes: photophysical and antimicrobial photoinactivation evaluation 

      Nonell, Santi; Agut Bonsfills, Montserrat; Ruiz González, Rubén; Reddi, Elena (International Journal of Molecular Sciences. Vol.16, n.11 (2015), p.27072-27086, 2015-11)
      Over the last decades, the number of pathogenic multi-resistant microorganisms has grown dramatically, which has stimulated the search for novel strategies to combat antimicrobial resistance. Antimicrobial ...
    • A near-infrared light-activatable Ru(ii)-coumarin photosensitizer active under hypoxic conditions 

      Ortega Forte, Enrique; Rovira, Anna; López Corrales, Marta; Hernández García, Alba; Ballester, Francisco José; Izquierdo García, Eduardo; Jordà Redondo, Mireia; Bosch, Manel; Nonell, Santi; Santana, María Dolores; Ruiz, José; Marchán, Vicente; Gasser, Gilles (Chemical Space 2023, 15(26), 2023-07-14)
      Photodynamic therapy (PDT) represents a promising approach for cancer treatment. However, the oxygen dependency of PDT to generate reactive oxygen species (ROS) hampers its therapeutic efficacy, especially ...
    • Do folate-receptor targeted liposomal photosensitizers enhance photodynamic therapy selectivity? 

      Nonell, Santi; García Díaz, María; Sagristá, M. Lluïsa; Villanueva, Ángeles; Stockert, Juan Carlos; Cañete, Magdalena; Casadó, Ana; Mora, Margarita (Biochimica et Biophysica Acta (BBA) -Biomembranes. Vol.1808, n.4 (2011), p.1063-1071, 2011-01)
      One of the current goals in photodynamic therapy research is to enhance the selective targeting of tumor cells in order to minimize the risk and the extension of unwanted side-effects caused by normal ...
    • Nanostructured AABB Zn (II) Phthalocyanines as Photodynamic Agents for Bacterial Inactivation 

      Paramio, Irene; Salazar, Ainhoa; Jordà Redondo, Mireia; Nonell, Santi; Torres, Tomás; De la Torre, Gema (Advanced Therapeutics 2023, 6 (11), 2300116, 2023-11)
      In this work, the ability of amphiphilic Phthalocyanine (Pc) photosensitizers (PS) (Zn(II)Pcs PS1, PS2, and PS3) to assemble into cationic nanoparticles in water and to photo-inactivate bacterial strains ...
    • Photodynamic synergistic effect of pheophorbide a and doxorubicin in combined treatment against tumoral cells 

      Nonell, Santi; Bresolí Obach, Roger; Ruiz González, Rubén; Milán, Paula; Stockert, Juan Carlos; Villanueva, Ángeles; Cañete, Magdalena (Cancers. Vol.9, n.2 (2017), 18, 2017-02)
      A combination of therapies to treat cancer malignancies is at the forefront of research with the aim to reduce drug doses (ultimately side effects) and diminish the possibility of resistance emergence ...
    • Porficenos para la fotoquimioterapia del cáncer y otras aplicaciones biomédicas 

      Nonell, Santi; Sánchez García, David; Borrell Bilbao, José Ignacio; Teixidó i Closa, Jordi; Arad, Ofir; Gavaldá, Ana; Rey, Óscar; Rubio, Noemi; Cañete, Magdalena; Juarranz, Ángeles; Villanueva, Ángeles; Stockert, Juan Carlos; Díaz Jiménez, Pablo J. (Afinidad. Vol.59, n.500 (2002), p.343-356, 2002)
      La terapia fotodinámica (PDT) o fotoquimioterapia del cáncer es una modalidad terapéutica que consiste en la aplicación de compuestos fotosensibilizadores que se acumulan preferentemente en tejidos ...
    • Singlet oxygen in antimicrobial photodynamic therapy: photosensitizer-dependent production and decay in E. coli 

      Nonell, Santi; Agut Bonsfills, Montserrat; Ragàs Amalrich, Xavier; He, Xin; Roxo-Rosa, Mónica; Rocha Gonsalves, António; Serra, Arménio C. (Molecules. Vol.18, n.3 (2013), p.2712-2725, 2013-02)
      Several families of photosensitizers are currently being scrutinized for antimicrobial photodynamic therapy applications. Differences in physical and photochemical properties can lead to different ...
    • Smart dual-functionalized gold nanoclusters for spatio-temporally controlled delivery of combined chemo- and photodynamic therapy 

      Nonell, Santi; Planas, Oriol; Gallavardin, Thibault; Nieves, Ingrid; Tabero, Andrea; Villanueva, Ángeles (Nanomaterials. Vol.10, n.12 (2020), 2474, 2020-12)
      We report the preparation of gold nanoclusters (AuNCs) as a delivery vehicle for the clinically approved photodynamic and chemotherapeutic agents Protoporphyrin IX (PpIX) and doxorubicin (DOX), respectively, ...
    • Synthesis, photophysical characterization and photoinduced antibacterial activity of methylene blue-loaded amino- and mannose-targeted mesoporous silica nanoparticles 

      Planas Marquès, Oriol; Bresolí Obach, Roger; Nos, Jaume; Gallavardin, Thibault; Ruiz González, Rubén; Agut Bonsfills, Montserrat; Nonell, Santi (Molecules. Vol.20, n.4 (2015), p.6284-6298, 2015-04)
      Over the last 20 years, the number of pathogenic multi-resistant microorganisms has grown steadily, which has stimulated the search for new strategies to combat antimicrobial resistance. Antimicrobial ...
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