Browsing by Subject "Ubiqüitina"

Now showing items 1-3 of 3

    • Different mechanisms that promote protein monoubiquitination 

      Crosas, Bernat; Puig Sàrries, Pilar (Afinidad. Vol.72, n.570 (2015), p.95-100, 2015-04)
      Protein monoubiquitination is a post-translational modification that consists of the conjugation of a single ubiquitin molecule to a target protein residue. Monoubiquitination regulates protein activity ...

    • Recent advances in the pharmacological targeting of ubiquitin-regulating enzymes in cancer 

      Montagut, Ana Maria; Armengol, Marc; Gorjón de Pablo, Gema; Estrada Tejedor, Roger; Borrell Bilbao, José Ignacio; Roué, Gaël (Seminars in Cell & Developmental Biology 2022, 132, 213-229, 2022-12)
      As a post-translational modification that has pivotal roles in protein degradation, ubiquitination ensures that intracellular proteins act in a precise spatial and temporal manner to regulate diversified ...

    • The potential of proteolytic chimeras as pharmalogical tools and therapeutic agents 

      Coll-Martínez, Bernat; Delgado, Antonio; Crosas, Bernat (Molecules. Vol.25, n.24 (2020), 5956, 2020-12)
      The induction of protein degradation in a highly selective and efficient way by means of druggable molecules is known as targeted protein degradation (TPD). TPD emerged in the literature as a revolutionary ...