Now showing items 1-3 of 3

    • Achieving red-light anticancer photodynamic therapy under hypoxia using Ir(iii)–COUPY conjugates 

      Ortega-Forte, Enrique; Rovira, Anna; Ashoo, Pezhman; Izquierdo García, Eduardo; Hally, Cormac; Abad-Montero, Diego; Jordà Redondo, Mireia; Vigueras Bautista, Gloria; Deyà, Alba; Hernández, José Luis; GALINO, JORGE; Bosch, Manel; Alberto, Marta Erminia; Francés-Monerris, Antonio; Nonell, Santi; Ruiz, Jose; Marchán, Vicente (Inorganic Chemistry Frontiers 2023, 12 (9), 2025-05-07)
      Despite the potential of photodynamic therapy (PDT), this oxygen-dependent oncological treatment is greatly restricted in the clinic by the well-known hypoxic feature of solid tumors. Here we provide ...
    • Octanol-water partition coefficients of highly hydrophobic photodynamic therapy drugs: a computational study 

      Estrada-Tejedor, Roger; Sabaté, Noemí; Broto Puig, Francesc; Nonell, Santi (Afinidad. Vol.70, n.564 (2013), p.250-256, 2013-10)
      Photodynamic therapy is a novel treatment for solid tumors based on the selective induction of cell death by the generation of cytotoxic reactive oxygen species within neoplastic tissues. Oxygen ...
    • Porficenos para la fotoquimioterapia del cáncer y otras aplicaciones biomédicas 

      Nonell, Santi; Sánchez-García, David; Borrell, Jose I.; Teixidó, Jordi; Arad, Ofir; Gavaldá, Ana; Rey, Óscar; Rubio, Noemi; Cañete, Magdalena; Juarranz, Ángeles; Villanueva, Ángeles; Stockert, Juan Carlos; Díaz Jiménez, Pablo J. (Afinidad. Vol.59, n.500 (2002), p.343-356, 2002)
      La terapia fotodinámica (PDT) o fotoquimioterapia del cáncer es una modalidad terapéutica que consiste en la aplicación de compuestos fotosensibilizadores que se acumulan preferentemente en tejidos ...