Now showing items 1-5 of 5

    • Dual stimuli-responsive polyphosphazene-based molecular gates for controlled drug delivery in lung cancer cells 

      Fornaguera Puigvert, Cristina; Borrós i Gómez, Salvador; Salinas, Yolanda; Kneidinger, Michael; Bruggemann, Oliver; Teasdale, Ian (RSC Advances. Vol.10, n.46 (2020), p.27305-27314, 2020-07)
      A switchable silane derived stimuli-responsive bottle-brush polyphosphazene (PPz) was prepared and attached to the surface of mesoporous silica nanoparticles (MSNs). The hybrid polymer with PEG-like ...
    • Effect of surface functionalization and loading on the mechanical properties of soft polymeric nanoparticles prepared by nano-emulsion templating 

      Dols-Perez, Aurora; Fornaguera Puigvert, Cristina; Feiner Gracia, Natalia; Grijalvo, Santiago; Solans, Conxita; Gomila, Gabriel (Colloids and Surfaces B: Biointerfaces 2023, 222, 113019, 2023-02)
      Drug and gene delivery systems based on polymeric nanoparticles offer a greater efficacy and a reduced toxicity compared to traditional formulations. Recent studies have evidenced that their internalization, ...
    • Liver-targeted nanoparticles delivering nitric oxide reduce portal hypertension in cirrhotic rats 

      Perramón Corominas, Meritxell; Navalón López, María; Fernández Varo, Guillermo; Moreno Lanceta, Alazne; García Jiménez, Rocío; Faneca Farrés, Joana; López-Moya, Mario; Fornaguera Puigvert, Cristina; García-Villoria, Judith; Morales-Ruiz, Manuel; Melgar Lesmes, Pedro; Borrós i Gómez, Salvador; Jiménez, Wladimiro (2024-01-13)
      Nitric oxide (NO) is a small vasodilator playing a key role in the pathogenesis of portal hypertension. Here, we assessed the potential therapeutic effect of a NO donor targeted to the liver by ...
    • Nanomedicine in non-small cell lung cancer: from conventional treatments to immunotherapy 

      Fornaguera Puigvert, Cristina; Borrós i Gómez, Salvador; García-Fernández, Coral (Cancers. Vol.12, n.6 (2020), 1609, 2020-06)
      Non-small cell lung cancer (NSCLC) remains the most common cause of cancer-related mortality. The heterogeneous nature of this disease hinders its diagnosis and treatment, requiring continuous advances ...
    • PExM: polyplex expansion microscopy for cell trafficking studies 

      Navalón López, María; Castells Colldeforns, Pau; Pujals, Sílvia; Fornaguera Puigvert, Cristina; Borrós i Gómez, Salvador (Nanoscale. 2024;16:11969-11976, 2024-06-03)
      Nanomedicine is a field at the intersection of nanotechnology and medicine, promising due to its potential to revolutionize healthcare. Despite its long trajectory, there is still a long road ahead for ...