Browsing by Subject 

Browsing by Subject "Metabolòmica"

Now showing items 1-4 of 4

    • Association between pre-diagnostic circulating lipid metabolites and colorectal cancer risk: a nested case–control study in the European Prospective Investigation into Cancer and Nutrition (EPIC) 

      Harewood, Rhea; Rothwell, Joseph A.; Bešević, Jelena; Viallon, Vivian; Achaintre, David; Gicquiau, Audrey; Rinaldi, Sabina; Wedekind, Roland; Prehn, Cornelia; Adamski, Jerzy; Schmidt, Julie A.; Jacobs, Inarie; Tjønneland, Anne; Olsen, Anja; Severi, Gianluca; Kaaks, Rudolf; Katzke, Verena Andrea; Schulze, Matthias B.; Prada, Marcela; Masala, Giovanna; Agnoli, Claudia; Panico, Salvatore; Sacerdote, Carlotta; Jakszyn, Paula; Sánchez, María-José; Castilla, Jesús; Chirlaque, Maria-Dolores; Aizpurua Atxega, Amaia; Van Guelpen, Bethany; Heath, Alicia K.; Papier, Keren; Tong, Tammy Y. N.; Summers, Scott A.; Playdon, Mary; Cross, Amanda J.; Keski-Rahkonen, Pekka; Chajès, Véronique; Murphy, Neil; Gunter, Marc J. (eBioMedicine, 2024, 101: 105024, 2024-03)
      Background Altered lipid metabolism is a hallmark of cancer development. However, the role of specific lipid metabolites in colorectal cancer development is uncertain. Methods In a case–control study ...

    • Determinants of blood acylcarnitine concentrations in healthy individuals of the European Prospective Investigation into Cancer and Nutrition 

      Wedekind, Roland; Rothwell, Joseph A.; Viallon, Vivian; Keski-Rahkonen, Pekka; Schmidt, Julie A.; Chajes, Veronique; Katzke, Vna; Johnson, Theron; Santucci de Magistris, Maria; Krogh, Vittorio; Amiano, Pilar; Sacerdote, Carlotta; Redondo-Sanchez, Daniel; Huerta, José María; Tjønneland, Anne; Pokharel, Pratik; Jakszyn, Paula; Tumino, Rosario; Ardanaz, Eva; Sandanger, Torkjel M.; Winkvist, Anna; Hultdin, Johan; Schulze, Matthias B.; Weiderpass, Elisabete; Gunter, Marc J.; Huybrechts, Inge; Scalbert, Augustin (Clinical nutrition, 2022, 41(8): 1735-1745, 2022-08)
      Background & aims Circulating levels of acylcarnitines (ACs) have been associated with the risk of various diseases such as cancer and type 2 diabetes. Diet and lifestyle factors have been shown to ...

    • Identifying metabolomic mediators of the physical activity and colorectal cancer relationship 

      Papadimitriou, Nikos; Kazmi, Nabila; Tsilidis, Konstantinos K.; Richmond, Rebecca C.; Lynch, Brigid M.; Bendinelli, Benedetta; Ricceri, Fulvio; Sánchez, Maria Jose; Trobajo-Sanmartín, Camino; Jakszyn, Paula; Simeon, Vittorio; Severi, Gianluca; Perduca, Vittorio; Truong, Therese; Ferrari, Pietro; Keski-Rahkonen, Pekka; Weiderpass, Elisabete; Eichelmann, Fabian; Schulze, Matthias B.; Katzke, Verena Andrea; Turzanski‑Fortner, Renée; Heath, Alicia K.; Aune, Dagfnn; Harewood, Rhea; Dahm, Christina C.; Llorente, Adrian; Gunter, Marc J.; Murphy, Neil; Lewis, Sarah Jayne (Cancer epidemiology, biomarkers and prevention, 2025, 34(4): 578-587, 2025-04)
      Background: Current evidence suggests higher physical activity (PA) levels are associated with a reduced risk of colorectal cancer. However, the mediating role of the circulating metabolome in this ...

    • Metabolic signatures of healthy lifestyle patterns and colorectal cancer risk in a European cohort 

      Rothwell, Joseph A.; Murphy, Neil; Bešević, Jelena; Kliemann, Nathalie; Jenab, Mazda; Ferrari, Pietro; Achaintre, David; Gicquiau, Audrey; Vozar, Beatrice; Scalbert, Augustin; Huybrechts, Inge; Freisling, Heinz; Prehn, Cornelia; Adamski, Jerzy; Cross, Amanda J.; Pala, Valeria Maria; Boutron-Ruault, Marie-Christine; Dahm, Christina C.; Overvad, Kim; Gram, Inger Torhild; Sandanger, Torkjel M.; Skeie, Guri; Jakszyn, Paula; Tsilidis, Kostas; Aleksandrova, Krasimira; Schulze, Matthias B.; Hughes, David J.; Van Guelpen, Bethany; Bodén, Stina; Sánchez, María-José; Schmidt, Julie A.; Katzke, Verena Andrea; Kühn, Tilman; Colorado-Yohar, Sandra; Tumino, Rosario; Bueno de Mesquita, H. Bas; Vineis, Paolo; Masala, Giovanna; Panico, Salvatore; Eriksen, Anne Kirstine; Tjønneland, Anne; Aune, Dagfnn; Weiderpass, Elisabete; Severi, Gianluca; Chajès, Véronique; Gunter, Marc J. (Clinical Gastroenterology and Hepatology, 2022, 20(5): e1061-e1082, 2022-05)
      Background & Aims Colorectal cancer risk can be lowered by adherence to the World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) guidelines. We derived metabolic signatures of ...