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Browsing by Subject "Medicaments antifibrinolítics"

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    • 1,2,3-Triazole Derivatives as Novel Antifibrinolytic Drugs 

      Bosch-Sanz, Oriol; Rabadà, Yvette; Biarnés Fontal, Xevi; Pedreño, Javier; Caveda, Luis; Balcells Camps, Mercedes; Martorell López, Jordi; Sánchez García, David (International Journal of Molecular Sciences, 23(23), 2022, 14942, 2022)
      Fibrinolysis is a natural process that ensures blood fluidity through the removal of fibrin deposits. However, excessive fibrinolytic activity can lead to complications in different circumstances, such ...

    • Mediterranean diet decreases the initiation of use of vitamin K epoxide reductase inhibitors and their associated cardiovascular risk: a randomized controlled trial 

      Castro-Barquero, Sara; Ribó-Coll, Margarita; Lassale, Camille; Tresserra-Rimbau, Anna; Castañer, Olga; Pintó Sala, Xavier; Martínez-González, Miguel Ángel, 1957-; Sorlí, José V.; Salas Salvadó, Jordi; Lapetra, José; Gómez-Gracia, Enrique; Alonso Gómez, Ángel M.; Fiol Sala, Miguel; Serra Majem, Lluís; Sacanella Meseguer, Emilio; Basterra-Gortari, Francisco Javier; Portolés, Olga; Babio, Nancy; Cofán Pujol, Montserrat; Ros Rahola, Emilio; Estruch Riba, Ramon; Hernáez, Álvaro (Nutrients, 2020, no. 12: 3895, 2020-12-19)
      Our aim is to assess whether following a Mediterranean Diet (MedDiet) decreases the risk of initiating antithrombotic therapies and the cardiovascular risk associated with its use in older individuals ...

    • Unravelling the Antifibrinolytic Mechanism of Action of the 1,2,3-Triazole Derivatives 

      Rabadà, Yvette; Bosch-Sanz, Oriol; Biarnés Fontal, Xevi; Pedreño, Javier; Caveda, Luis; Sánchez García, David; Martorell López, Jordi; Balcells Camps, Mercedes (International Journal of Molecular Sciences. 2024;25(13):7002, 2024-06-26)
      A new family of antifibrinolytic drugs has been recently discovered, combining a triazole moiety, an oxadiazolone, and a terminal amine. Two of the molecules of this family have shown activity that is ...